U.S. Department of Health and Human Services
Guillermo Arreaza-Rubin

 Contact Info

Tel: 301-594-4724
Email: arreazag@mail.nih.gov

 Select Experience

  • Scientific DirectorDiabetogen Biosciences, Inc., London, Ontario, Canada2000-2005
  • Senior Research AssociateThe Robarts Research Institute, Autoimmunity/ Diabetes Group, University of Western Ontario1998-2000
  • Postdoctoral FellowshipThe Robarts Research Institute, Autoimmunity/Diabetes Group, University of Western Ontario1994-1997
  • Research FellowshipEndocrinology Research Laboratory, The Wellesley Hospital, Department of Medicine, University of Toronto1991-1994
  • ResidencyUniversity Hospital, Central University of Venezuela1988-1991

Guillermo A. Arreaza-Rubin, M.D.

Program Director, Division of Diabetes, Endocrinology, and Metabolic Diseases

Current Responsibilities and Activities

As program director studying the clinical immunology of diabetes, I oversee a variety of research projects designed to improve treatment of this disease.  My responsibilities include directing the Small Business Innovation Research/Small Business Technology Transfer Research (SBIR/STTR) program—which supports innovative research by small businesses that have the potential for commercialization—in areas related to immunology and diabetes.  These areas include:  drug discovery for diabetes and other endocrine diseases; new technologies for islet isolation, stem cell/regeneration, and transplantation; immune modulatory agents for the primary and secondary prevention of diabetes; inflammatory aspects of type 2 diabetes, insulin resistance, and obesity; and closed-loop systems/artificial pancreas development.  I oversee research on glucose sensors and drug development and serve as co-director of the Rapid Access to Intervention Development program, a cooperative effort to facilitate translation of new and promising therapies.  My duties also include acting as the executive secretary of the Clinical Islet Transplantation Consortium Data and Safety Monitoring Board, and I represent the NIDDK on several trans-NIH working groups on metabolic monitoring, inflammatory processes, and autoimmunity.

​Research Programs

Bioengineering, Biotechnology, and Imaging as applied to Diabetes, Metabolic and Endocrine Diseases
This program supports research that is aimed at applying sophisticated, cutting-edge technologies to advance the understanding of the mechanisms that underlie diabetes and other endocrine and metabolic diseases

Endocrine Pancreas
The Endocrine Pancreas program supports research on the basic biology, development, and function of the endocrine pancreas as well as clinical studies on islet transplantation for the treatment of type 1 diabetes

Current Committee Memberships

  • NIH Steering Committee of the Technologies for Metabolic Monitoring Interagency InitiativeNIDDK Representative
  • NIH Interagency Artificial Pancreas Working GroupNIDDK Representative
  • Office on Research on Women’s Health Regulation of Inflammatory Responses Working GroupNIDDK Representative
  • NIH-Immunology Interest GroupMember
  • NIH-Mucosal Immunology Interest GroupMember
  • Type 1 Diabetes Working GroupMember
  • Autoimmunity Working GroupMember
  • DEM Clinical Working GroupMember
  • Beta Cell Working GroupMember
  • DEM SBIR/STTR Working GroupCoordinator