U.S. Department of Health and Human Services
Guillermo Arreaza-Rubin

 Contact Info

Tel: +1 301 594 4724
Email: arreazag@mail.nih.gov

 Select Experience

Scientific Director, Diabetogen Biosciences, Inc., London, Ontario, Canada, 2000-2005

Senior Research Associate, The Robarts Research Institute, Autoimmunity/ Diabetes Group, University of Western Ontario, 1998-2000

Postdoctoral Fellowship, The Robarts Research Institute, Autoimmunity/Diabetes Group, University of Western Ontario, 1994-1997

Research Fellowship, Endocrinology Research Laboratory, The Wellesley Hospital, Department of Medicine, University of Toronto, 1991-1994

Residency, University Hospital, Central University of Venezuela, 1988-1991

Guillermo A. Arreaza-Rubin, M.D.

Program Director, Division of Diabetes, Endocrinology, and Metabolic Diseases

Current Responsibilities and Activities

As program director studying the clinical immunology of diabetes, I oversee a variety of research projects designed to improve treatment of this disease.  My responsibilities include directing the Small Business Innovation Research/Small Business Technology Transfer Research (SBIR/STTR) program—which supports innovative research by small businesses that have the potential for commercialization—in areas related to immunology and diabetes.  These areas include:  drug discovery for diabetes and other endocrine diseases; new technologies for islet isolation, stem cell/regeneration, and transplantation; immune modulatory agents for the primary and secondary prevention of diabetes; inflammatory aspects of type 2 diabetes, insulin resistance, and obesity; and closed-loop systems/artificial pancreas development.  I oversee research on glucose sensors and drug development and serve as co-director of the Rapid Access to Intervention Development program, a cooperative effort to facilitate translation of new and promising therapies.  My duties also include acting as the executive secretary of the Clinical Islet Transplantation Consortium Data and Safety Monitoring Board, and I represent the NIDDK on several trans-NIH working groups on metabolic monitoring, inflammatory processes, and autoimmunity.

​Research Programs

Diabetes and Endocrine Disease Bioengineering, Biotechnology, and Imaging
This program supports research that is aimed at applying sophisticated, cutting-edge technologies to advance the understanding of the mechanisms that underlie diabetes and other endocrine and metabolic diseases

Endocrine Pancreas
The Endocrine Pancreas program supports research on the basic biology, development, and function of the endocrine pancreas as well as clinical studies on islet transplantation for the treatment of type 1 diabetes

Committee Membership

NIH Steering Committee of the Technologies for Metabolic Monitoring Interagency Initiative, NIDDK Representative

NIH Interagency Artificial Pancreas Working Group, NIDDK Representative

Office on Research on Women’s Health Regulation of Inflammatory Responses Working Group, NIDDK Representative

NIH-Immunology Interest Group, Member

NIH-Mucosal Immunology Interest Group, Member​

Type 1 Diabetes Working Group, Member

Autoimmunity Working Group, Member

DEM Clinical Working Group, Member

Beta Cell Working Group, Member

DEM SBIR/STTR Working Group, Coordinator