I serve as director of the Immunobiology of Type 1 Diabetes and Autoimmune Endocrine Diseases Program. My portfolio includes basic and clinical research on the pathogenic mechanisms of autoimmunity in type 1 diabetes and autoimmune thyroid diseases.
I am the Project Scientist for Type 1 Diabetes TrialNet—an international consortium for the conduct of clinical trials for the prevention and reversal of type 1 diabetes. My special interest is in facilitating biomarker discovery.
I am the Program Director for The Environmental Determinants of Diabetes in Youth (TEDDY), an international consortium of scientists studying a cohort of over 8,000 children with genetic risk for type 1 diabetes. The TEDDY study follows the children from birth to age 15, and collects data on their environmental exposures, including diet, infections, psychosocial factors, microbiome, and metabolome, etc. with respect to autoimmunity and progression to disease.