U.S. Department of Health and Human Services
Lisa Spain

 Contact Info

Tel: 301-451-9871
Email: spainl@mail.nih.gov

 Select Experience

  • Scientist IIAdjunct Associate Professor, Holland Laboratories for Biomedical Sciences, American Red Cross, George Washington University Medical School1999-2004
  • Assistant ProfessorWistar Institute, University of Pennsylvania1993-1999
  • Postdoctoral FellowDepartment of Cellular and Molecular Biology, Harvard University1991-1993
  • Ph.D.Massachusetts Institute of Technology1990

Lisa M. Spain, Ph.D.

Program Director, Division of Diabetes, Endocrinology, and Metabolic Diseases

Current Responsibilities and Activities

I serve as director of the Clinical Research in Type 1 Diabetes and Pathophysiology of Diabetes and Metabolic Disease programs.  My portfolio includes basic and clinical research on the pathogenic mechanisms of autoimmunity in type 1 diabetes and autoimmune thyroid diseases.

I am the project scientist for Type 1 Diabetes TrialNet—an international consortium for the conduct of clinical trials for the prevention and reversal of type 1 diabetes.  My special interest is in facilitating biomarker discovery.

​Research Programs

Clinical Research in Type 1 Diabetes
This program supports clinical research that addresses the determinants, etiology, progression, prevention, and treatment of type 1 diabetes in children and adults

Pathophysiology of Diabetes and Metabolic Disease
This program supports basic and clinical research that addresses the pathophysiology of metabolic diseases, including the etiology of type 1 diabetes and other autoimmune endocrine diseases

Current Committee Memberships

  • The Biomarkers Consortium: Inflammation & Immunity Steering CommitteeNIDDK Representative
  • NIH Autoimmune Disease Coordinating CommitteeNIDDK Representative
  • NIDDK Clinical Sciences Working GroupMember
  • NIDDK/DEM Autoimmunity/Transplantation Working GroupMember