U.S. Department of Health and Human Services
Robert Karp
 

 Contact Info

 
Tel: 301-451-8875
Email: karpr@mail.nih.gov
 

 Select Experience

 
  • DirectorGenetics Program, NIAAA, NIH1991-2001
  • Associate DirectorEukaryotic and Prokaryotic Genetics Programs, National Science Foundation1988-1990
  • Research Associate/LecturerBiological Laboratories, Harvard University1983-1986
  • Postdoctoral FellowDepartment of Genetics, University of Cambridge, United Kingdom1978-1982
  • Ph.D. Stanford University1978

Robert Karp

Program Director, Division of Digestive Diseases and Nutrition

Current Responsibilities and Activities

I am program director for the Genetics and Genomics programs in the Division of Digestive Diseases and Nutrition.  In this role, I oversee a research portfolio on genetics and genomics as they relate to obesity, gastrointestinal diseases, liver and pancreatic diseases, and nutrition.  My responsibilities include serving as project officer for the Inflammatory Bowel Disease Genetics Consortium.  This Consortium consists of investigators from multiple sites who are conducting genetic association and gene expression studies to elucidate the pathophysiological mechanisms of inflammatory bowel disease.  I also am co-project officer of the NIDDK Repositories of biosamples and data collected in clinical studies, which the NIDDK makes available to the wider research community.

I serve on the Management Committee for the trans-NIH Human Microbiome Project (HMP), an initiative of the NIH Common Fund.  The HMP has supported censes of the microflora of 17 body sites in a population of healthy individuals, reference sequences of the genomes of about 1,000 strains of commensal bacteria, development of new technology and computational methods for analysis of microbiome data, and projects to explore the relationship between alterations in the microbiome and a range of diseases.  It is about to support the production of a large integrated metagenomic, transcriptomic, proteomic, and metabolomic dataset relating changes in the microbiome to a disease (the identity of which remains to be determined).

​Research Programs

Digestive Diseases Genetics and Genomics
The Digestive Diseases, Genetics, and Genomics program supports research to identify genes that influence normal development, function, and diseases of the gastrointestinal tract

Gastrointestinal Immunology, Inflammation, and Inflammatory Diseases
The Gastrointestinal Immunology, Inflammation, and Inflammatory Diseases program supports basic, clinical, and translational research on mucosal immunology, intestinal immunity, and inflammation in gastrointestinal diseases and conditions

Gastrointestinal Microbiology and Infectious Diseases
This program supports basic, clinical, and translational research on the gut microbiota, pathogenic organisms that reside in the gastrointestinal tract

Liver Diseases Genetics and Genomics
The Liver Diseases Genetics and Genomics program supports research to identify genes that influence normal development, function, and diseases of the liver

Nutrition and Obesity Genetics and Genomics
The Nutrition and Obesity Genetics and Genomics program supports research to identify genes that influence obesity, human nutrition and nutrient metabolism, and nutritional disorders

Current Committee Memberships

  • NIH Human Microbiome Working GroupNIDDK Representative
  • NIDDK Genomics Interest GroupMember
  • NIDDK Obesity Research Working GroupMember