U.S. Department of Health and Human Services
Arthur Sherman
 

 Contact Info

 
Tel: 301-496-4325
Email: arthurs@helix.nih.gov
 

 Select Experience

 
  • Ph.D.New York University1986
  • M.S.New York University1983
  • B.A.Cornell University1973
 

 Related Links

 
Specialties
  • Cell Biology/Cell Signaling
  • Computational Biology/Bioinformatics/Biostatistics/Mathematics
  • Neuroscience/Neurophysiology/Neurodevelopment

​Research Images

Images or videos appear below. Clicking images or videos provides an expanded view.

TitleDescriptionImage
Pancreatic Beta Cell Signaling PathwaysThis schematic provides an illustration of some of the pathways included in our models.  See Sherman, Mathematical Biosci. 227:12-19, 2007 for details.Pancreatic Beta Cell Signaling PathwaysEnlarge
Sliding barsThis schematic model depicts changes in islet activity due to step increases in glucose concentration.  A sliding threshold representation of the dual oscillator model dynamics is depicted left, with measured islet Ca2+ concentration and corresponding model simulations, right.   The models are from Bertram et al, Am. J. Physiol. Endocrinol. Metab. 293:890-900.Sliding barsEnlarge
Cover Art, J. Gen. Physiol., July, 2011The image depicts bifurcation diagrams and time courses of four types of bursting oscillations made by varying parameters in a simplified Chay-Keizer model.  Clockwise from top left the diagrams depict a plateau without spikes, a square-wave bursting (beta cell pattern), a pseudo-plateau bursting (pituitary somatotroph pattern), and a parabolic bursting (like R-15 neuron of Aplysia).Cover Art, J. Gen. Physiol., July, 2011Enlarge