U.S. Department of Health and Human Services
Constance Tom Noguchi

 Contact Info

Tel: 301-496-1163
Email: cnoguchi@helix.nih.gov

 Select Experience

  • Ph.D.The George Washington University1975
  • B.A.University of California, Berkeley1970

 Related Links


    • Cell Biology/Cell Signaling

    ​Research Images

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    Imaging White Fat in MiceWhole body image of fat in normal wild type mice (WT) and obese mice with erythropoietin receptor restricted to erythroid cells (EpoR).Imaging White Fat in MiceEnlarge
    Erythropoietin stimulates red blood cell productionErythropoietin (EPO) is produced in the kidney, regulates the daily production of 200 billion red blood cells, and is inducible by low oxygen or hypoxia.Erythropoietin stimulates red blood cell productionEnlarge
    Erythropoietin receptor expression in neural cellsErythropoietin receptor (EpoR) is expressed on neural progenitor cells and neurons.Erythropoietin receptor expression in neural cellsEnlarge
    Multi-tissue response to erythropoietinErythropoietin regulates oxygen delivery through red blood cell production.  In model systems it stimulates other select tissues to affect oxygen consumption and metabolic response.Multi-tissue response to erythropoietinEnlarge
    Hypothalamus expression of erythropoietin receptorErythropoietin receptor (EpoR) co-localizes to proopiomelanocortin (POMC), producing neurons in the hypothalamus that regulate food intake and energy expenditure.Hypothalamus expression of erythropoietin receptorEnlarge