U.S. Department of Health and Human Services
Elisabetta Mueller

 Contact Info

Tel: 301-594-6797
Email: elisabettam@mail.nih.gov

 Select Experience

  • InvestigatorNIDDK, NIH2004–Present
  • Instructor in Cell BiologyHarvard Medical School1998–2004
  • Postdoctoral FellowCell Biology, Harvard Medical School1995–1998
  • LaureaBiology, University of Padova1988
  • Ph.D.Genetics, University of Padova1995

 Related Links


    Elisabetta Mueller, Ph.D.

    Investigator, Genetics of Development and Disease Branch, Office of the Chief
    • Cell Biology/Cell Signaling
    • Genetics/Genomics
    • Molecular Biology/Biochemistry


    A selection of recent and significant publications can be viewed below.

    Teng R, Gavrilova O, Suzuki N, Chanturiya T, Schimel D, Hugendubler L, Mammen S, Yver DR, Cushman SW, Mueller E, Yamamoto M, Hsu LL, Noguchi CT. Disrupted erythropoietin signalling promotes obesity and alters hypothalamus proopiomelanocortin production. Nat Commun. 2011 Nov 1; 2:520. [Full Text/Abstract]
    Meruvu S, Hugendubler L, Mueller E. Regulation of adipocyte differentiation by the zinc finger protein ZNF638. J. Biol. Chem. 2011 Jul 29; 286:26516-23. [Full Text/Abstract]
    Bagattin A, Hugendubler L, Mueller E. Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis. Proc. Natl. Acad. Sci. U.S.A. 2010 Nov 23; 107:20376-81. [Full Text/Abstract]
    Di Pietro N, Panel V, Hayes S, Bagattin A, Meruvu S, Pandolfi A, Hugendubler L, Fejes-Tóth G, Naray-Fejes-Tóth A, Mueller E. Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1. Mol. Endocrinol. 2010 Feb; 24:370-80. [Full Text/Abstract]
    Skarulis MC, Celi FS, Mueller E, Zemskova M, Malek R, Hugendubler L, Cochran C, Solomon J, Chen C, Gorden P. Thyroid hormone induced brown adipose tissue and amelioration of diabetes in a patient with extreme insulin resistance. J. Clin. Endocrinol. Metab. 2010 Jan; 95:256-62. [Full Text/Abstract]
    Leslie DS, Dascher CC, Cembrola K, Townes MA, Hava DL, Hugendubler LC, Mueller E, Fox L, Roura-Mir C, Moody DB, Vincent MS, Gumperz JE, Illarionov PA, Besra GS, Reynolds CG, Brenner MB. Serum lipids regulate dendritic cell CD1 expression and function. Immunology. 2008 Nov; 125:289-301. [Full Text/Abstract]
    Hong JH, Hwang ES, McManus MT, Amsterdam A, Tian Y, Kalmukova R, Mueller E, Benjamin T, Spiegelman BM, Sharp PA, Hopkins N, Yaffe MB. TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science. 2005 Aug 12; 309:1074-8. [Full Text/Abstract]
    Drori S, Girnun GD, Tou L, Szwaya JD, Mueller E, Xia K, Shivdasani RA, Spiegelman BM. Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev. 2005 Feb 1; 19:362-75. [Full Text/Abstract]
    Smith MR, Manola J, Kaufman DS, George D, Oh WK, Mueller E, Slovin S, Spiegelman B, Small E, Kantoff PW. Rosiglitazone versus placebo for men with prostate carcinoma and a rising serum prostate-specific antigen level after radical prostatectomy and/or radiation therapy. Cancer. 2004 Oct 1; 101:1569-74. [Full Text/Abstract]
    Salma N, Xiao H, Mueller E, Imbalzano AN. Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the peroxisome proliferator-activated receptor gamma nuclear hormone receptor. Mol. Cell. Biol. 2004 Jun; 24:4651-63. [Full Text/Abstract]
    Gupta RA, Sarraf P, Mueller E, Brockman JA, Prusakiewicz JJ, Eng C, Willson TM, DuBois RN. Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms. J. Biol. Chem. 2003 Jun 20; 278:22669-77. [Full Text/Abstract]
    Burstein HJ, Demetri GD, Mueller E, Sarraf P, Spiegelman BM, Winer EP. Use of the peroxisome proliferator-activated receptor (PPAR) gamma ligand troglitazone as treatment for refractory breast cancer: a phase II study. Breast Cancer Res. Treat. 2003 Jun; 79:391-7. [Full Text/Abstract]
    Mueller E, Drori S, Aiyer A, Yie J, Sarraf P, Chen H, Hauser S, Rosen ED, Ge K, Roeder RG, Spiegelman BM. Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms. J. Biol. Chem. 2002 Nov 1; 277:41925-30. [Full Text/Abstract]
    Girnun GD, Smith WM, Drori S, Sarraf P, Mueller E, Eng C, Nambiar P, Rosenberg DW, Bronson RT, Edelmann W, Kucherlapati R, Gonzalez FJ, Spiegelman BM. APC-dependent suppression of colon carcinogenesis by PPARgamma. Proc. Natl. Acad. Sci. U.S.A. 2002 Oct 15; 99:13771-6. [Full Text/Abstract]