U.S. Department of Health and Human Services
Gertraud Robinson

 Contact Info

Tel: +1 301 496 5004
Email: gertraur@bdg10.niddk.nih.gov

 Training and Experience

Ph.D., University of Salzburg, 1981

Diploma, Agricultural University Vienna, 1973

Staff Scientist, Laboratory of Genetics and Physiology, NIDDK, NIH, 1997-present

Editorial Board, Breast Cancer Research, 1999-present

Study Section, Breast Cancer Program, U.S. Department of Defense, 1999-2000

Senior Staff Fellow, Developmental Biology Section, NIDDK, NIH, 1993-1997

Senior Fellowship, National Research Council, 1990-1993

Group Leader, Institute of Molecular Biology, Austrian Academy of Sciences, 1986-1989

Postdoctorate, NIDDK, NIH, 1984-1986

International Fogarty Fellowship, NCI, NIH, 1983-1984

 Related Links

Specialties: Cell Biology/Cell Signaling, Chromosome Biology/Epigenetics, Developmental Biology, Genetics/Genomics

Research Summary

Research Goal

We use emerging new technologies to identify the genes that regulate development of the mammary gland to learn about the basic mechanisms of transcriptional control that lead to cell growth and differentiation. 

Current Research

Since my days as a graduate student with Klaus Kratochwil in Salzburg, Austria, I have been studying many aspects of mammary gland development.  Using targeted gene strains, I analyzed a number of mutants with defects in mammary gland development to identify genes that regulate ductal and alveolar development during puberty and pregnancy.  Among them are activinB, the transcription factors C/EBPbeta, and ID-2, Shh, connexins, SOCS3, and Notch signals.  Presently, I am investigating the role of the Jak2/Stat5 pathway in the proliferation and differentiation of secretory epithelial cells.  I also study the epigenetic alterations that regulate these events.  I collaborate with several researchers who perform mammary epithelial transplantations, particularly of anlagen from mutants that do not survive to adulthood.​

Applying our Research

Understanding the genetic pathways that regulate development will give us information on ways to interfere with the deregulated growth that causes cancers.