U.S. Department of Health and Human Services
Gertraud Robinson

 Contact Info

Tel: 301-496-4005
Email: gertraud.robinson@nih.gov

 Select Experience

  • Editorial BoardBreast Cancer Research1999-present
  • Study SectionBreast Cancer Program, U.S. Department of Defense1999-2000
  • Staff ScientistLaboratory of Genetics and Physiology, NIDDK, NIH1997-present
  • Senior Staff FellowDevelopmental Biology Section, NIDDK, NIH1993-1997
  • Senior FellowshipNational Research Council1990-1993
  • Group LeaderInstitute of Molecular Biology, Austrian Academy of Sciences1986-1989
  • PostdoctorateNIDDK, NIH1984-1986
  • International Fogarty FellowshipNCI, NIH1983-1984
  • DiplomaAgricultural University Vienna1973
  • Ph.D.University of Salzburg1981

 Related Links

  • Cell Biology/Cell Signaling
  • Chromosome Biology/Epigenetics
  • Developmental Biology
  • Genetics/Genomics

Research Summary

Research Goal

We use emerging new technologies to identify the genes that regulate development of the mammary gland to learn about the basic mechanisms of transcriptional control that lead to cell growth and differentiation. 

Current Research

Since my days as a graduate student with Klaus Kratochwil in Salzburg, Austria, I have been studying many aspects of mammary gland development.  Using targeted gene strains, I analyzed a number of mutants with defects in mammary gland development to identify genes that regulate ductal and alveolar development during puberty and pregnancy.  Among them are activinB, the transcription factors C/EBPbeta, and ID-2, Shh, connexins, SOCS3, and Notch signals.  Presently, I am investigating the role of the Jak2/Stat5 pathway in the proliferation and differentiation of secretory epithelial cells.  I also study the epigenetic alterations that regulate these events.  I collaborate with several researchers who perform mammary epithelial transplantations, particularly of anlagen from mutants that do not survive to adulthood.​

Applying our Research

Understanding the genetic pathways that regulate development will give us information on ways to interfere with the deregulated growth that causes cancers.