U.S. Department of Health and Human Services
Jenny Hinshaw
 

 Contact Info

 
Tel: 301-594-0842
Email: jennyh@helix.nih.gov
 

 Select Experience

 
  • Ph.D.Brown University1989
  • B.A.Wellesley College1982
 

 Related Links

 
    Specialties
    • Cell Biology/Cell Signaling
    • Structural Biology

    Research in Plain Language

    Animal cells are protected from their surrounding environment by a lipid membrane. However, the membrane must allow external materials, such as nutrients and chemical messengers, to get into the cell. One way this is achieved is through a process called endocytosis, where a small part of the cell membrane folds inward into a pit that pinches off, forming a sack that is free to move through the cell. The protein dynamin is crucial for this process. Our studies and others have shown that dynamin wraps around and constricts the necks of the membrane pits, which helps seal the free-moving sacks.