U.S. Department of Health and Human Services
John Hanover
 

 Contact Info

 
Tel: 301-496-0943
Email: jah@helix.nih.gov
 

 Select Experience

 
  • Ph.D.Johns Hopkins University School of Medicine1981
  • B.S.University of Tulsa1976
 

 Related Links

 
 
Specialties
  • Cell Biology/Cell Signaling
  • Genetics/Genomics
  • Molecular Biology/Biochemistry

‚ÄčPublications

A selection of recent and significant publications can be viewed below.

Publications
Ranuncolo SM, Ghosh S, Hanover JA, Hart GW, Lewis BA. Evidence of the involvement of O-GlcNAc-modified human RNA polymerase II CTD in transcription in vitro and in vivo. J Biol Chem. 2012 Jul 6; 287:23549-61. [Full Text/Abstract]
Hanover JA, Krause MW, Love DC. Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation. Nat Rev Mol Cell Biol. 2012 Apr 23; 13:312-21. [Full Text/Abstract]
Keembiyehetty CN, Krzeslak A, Love DC, Hanover JA. A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome. J Cell Sci. 2011 Aug 15; 124:2851-60. [Full Text/Abstract]
Mondoux MA, Love DC, Ghosh SK, Fukushige T, Bond M, Weerasinghe GR, Hanover JA, Krause MW. O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans. Genetics. 2011 Jun; 188:369-82. [Full Text/Abstract]
Hanover JA. A versatile sugar transferase makes the cut. Cell. 2011 Feb 4; 144:321-3. [Full Text/Abstract]
Hanover JA. Epigenetics gets sweeter: O-GlcNAc joins the "histone code". Chem Biol. 2010 Dec 22; 17:1272-4. [Full Text/Abstract]
Sekine O, Love DC, Rubenstein DS, Hanover JA. Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis. J Biol Chem. 2010 Dec 3; 285:38684-91. [Full Text/Abstract]
Kim EJ, Love DC, Darout E, Abdo M, Rempel B, Withers SG, Rablen PR, Hanover JA, Knapp S. OGA inhibition by GlcNAc-selenazoline. Bioorg Med Chem. 2010 Oct 1; 18:7058-64. [Full Text/Abstract]
Love DC, Krause MW, Hanover JA. O-GlcNAc cycling: emerging roles in development and epigenetics. Semin Cell Dev Biol. 2010 Aug; 21:646-54. [Full Text/Abstract]
Love DC, Ghosh S, Mondoux MA, Fukushige T, Wang P, Wilson MA, Iser WB, Wolkow CA, Krause MW, Hanover JA. Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity. Proc Natl Acad Sci U S A. 2010 Apr 20; 107:7413-8. [Full Text/Abstract]
Hanover JA, Krause MW, Love DC. The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine. Biochim Biophys Acta. 2010 Feb; 1800:80-95. [Full Text/Abstract]
Lazarus BD, Love DC, Hanover JA. O-GlcNAc cycling: implications for neurodegenerative disorders. Int J Biochem Cell Biol. 2009 Nov; 41:2134-46. [Full Text/Abstract]
Hanover JA, Love DC, Prinz WA. Calmodulin-driven nuclear entry: trigger for sex determination and terminal differentiation. J Biol Chem. 2009 May 8; 284:12593-7. [Full Text/Abstract]
Chen S, Whetstine JR, Ghosh S, Hanover JA, Gali RR, Grosu P, Shi Y. The conserved NAD(H)-dependent corepressor CTBP-1 regulates Caenorhabditis elegans life span. Proc Natl Acad Sci U S A. 2009 Feb 3; 106:1496-501. [Full Text/Abstract]
Krawczyk E, Suprynowicz FA, Liu X, Dai Y, Hartmann DP, Hanover J, Schlegel R. Koilocytosis: a cooperative interaction between the human papillomavirus E5 and E6 oncoproteins. Am J Pathol. 2008 Sep; 173:682-8. [Full Text/Abstract]
Krawczyk E, Hanover JA, Schlegel R, Suprynowicz FA. Karyopherin beta3: a new cellular target for the HPV-16 E5 oncoprotein. Biochem Biophys Res Commun. 2008 Jul 11; 371:684-8. [Full Text/Abstract]
Wesierska-Gadek J, Klima A, Ranftler C, Komina O, Hanover J, Invernizzi P, Penner E. Characterization of the antibodies to p62 nucleoporin in primary biliary cirrhosis using human recombinant antigen. J Cell Biochem. 2008 May 1; 104:27-37. [Full Text/Abstract]