U.S. Department of Health and Human Services
Jürgen Wess
 

 Contact Info

 
Tel: 301-402-3589
Email: jurgenw@helix.nih.gov
 

 Select Experience

 
  • ChiefMolecular Signaling Section, Laboratory of Biological Chemistry, NIDDK, NIH1998
  • HeadG Protein-Coupled Receptor Unit, NIDDK, NIH1993-1997
  • HeadG Protein-Coupled Receptor Unit, NINDS, NIH1991-1993
  • Postdoctoral FellowJoint Appointment at NIMH and NINDS, NIH1988-1991
  • Ph.D.Johann Wolfgang-Goethe University1987
 

 Related Links

 

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    Correlation ID:f7e274ea-35d3-4084-ab4b-649c7d047926
    Specialties
    • Cell Biology/Cell Signaling
    • Molecular Biology/Biochemistry
    • Molecular Pharmacology/Toxicology

    ​Resources

    Patents, materials, and other research resources appear below. Some resources may be available for use through Material Transfer Agreements (MTAs) or licensing agreements.

    Resource Name Description
    M3 Muscarinic Receptor Knockout mice are hypophagic, lean, and have improved glucose tolerance and insulin sensitivity. (Mutant Mouse: M3 Muscarinic receptor KO (Chrm3 tm1Jwe) Mouse)

    M3 Muscarinic Receptor Knockout mice are hypophagic, lean, and have improved glucose tolerance and insulin sensitivity.

    The five Muscarinic Acetylcholine (ACh) receptors are G-protein coupled receptors (M1R-M5R). M1R, M3R and M5R selectively couple to…

    (Summary)
    M1 Muscarinic receptor KO (Chrm1 tm1Jwe) Mouse (Mutant Mouse: Chrm1 (Cholinergic Receptor, muscarinic 1))

    M1 Muscarinic Receptor Knockout: support involvement in cognitive processes.

    The five Muscarinic Acetylcholine (ACh) receptors are G-protein coupled receptors (M1R-M5R). M1R, M3R and M5R selectively couple to Gq/G11; M2R and M4R selectively couple to…

    (Summary)
    M2 Muscarinic receptor KO (Chrm2 tm1Jwe) Mouse (Mutant Mouse: Chrm2)

    M2 Muscarinic Receptor Knockout: role in learning and memory, and mediating analgesic effectsof muscarinic agonists

    The five Muscarinic Acetylcholine (ACh) receptors are G-protein coupled receptors (M1R-M5R). M1R, M3R and M5R selectively couple to…

    (Summary)
    M4 Muscarinic receptor KO (Chrm4 tm1Jwe) Mouse (Mutant Mouse: Chrm4)

    M4 Muscarinic Receptor Knockout: Activation of M4R may reduce the reinforcing effect of drugs of abuse, and contribute to the analgesic effects observed after administration of muscarinic agonists.

    The five Muscarinic Acetylcholine (ACh) receptors are…

    (Summary)
    M5 Muscarinic receptor KO (Chrm5 tm1Jwe) Mouse (Mutant Mouse: Chrm5)

    M5 Muscarinic Receptor Knockout: Deficiency of M5Rs reduces drug-seeking behavior.

    The five Muscarinic Acetylcholine (ACh) receptors are G-protein coupled receptors (M1R-M5R). M1R, M3R and M5R selectively couple to Gq/G11; M2R and M4R selectively…

    (Summary)
    View Additional Research Resources

    Clinical Trials

    Open studies conducted by NIDDK Principal Investigators appear below that are currently recruiting, not yet recruiting, or available for expanded access.

    Study Title
    There are no associated clinical trials.
    Search for more clinical trials at ClinicalTrials.gov