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Enlaces a nuestra información en español sobre la diabetes, enfermedades digestivas, enfermedades renales, control de peso, enfermedades urológicas, enfermedades endocrinas y metabólicas, y enfermedades hematológicas
Director and deputy director biographies, Dr. Rodgers' vision statement, and the Director's Update newsletter
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Patents, materials, and other research resources appear below. Some resources may be available for use through Material Transfer Agreements (MTAs) or licensing agreements.
M3 Muscarinic Receptor Knockout mice are hypophagic, lean, and have improved glucose tolerance and insulin sensitivity.
The five Muscarinic Acetylcholine (ACh) receptors are G-protein coupled receptors (M1R-M5R). M1R, M3R and M5R selectively couple to…
M1 Muscarinic Receptor Knockout: support involvement in cognitive processes.
The five Muscarinic Acetylcholine (ACh) receptors are G-protein coupled receptors (M1R-M5R). M1R, M3R and M5R selectively couple to Gq/G11; M2R and M4R selectively couple to…
M2 Muscarinic Receptor Knockout: role in learning and memory, and mediating analgesic effectsof muscarinic agonists
M4 Muscarinic Receptor Knockout: Activation of M4R may reduce the reinforcing effect of drugs of abuse, and contribute to the analgesic effects observed after administration of muscarinic agonists.
The five Muscarinic Acetylcholine (ACh) receptors are…
M5 Muscarinic Receptor Knockout: Deficiency of M5Rs reduces drug-seeking behavior.
The five Muscarinic Acetylcholine (ACh) receptors are G-protein coupled receptors (M1R-M5R). M1R, M3R and M5R selectively couple to Gq/G11; M2R and M4R selectively…
Open studies conducted by NIDDK Principal Investigators appear below that are currently recruiting, not yet recruiting, or available for expanded access.