U.S. Department of Health and Human Services
Kiyoshi Mizuuchi

 Contact Info

Tel: 301-496-8154
Email: kmizu@helix.nih.gov

 Select Experience

  • D.S. (Ph.D.)Osaka University1972
  • M.S.Osaka University1969
  • B.S.Osaka University1967

 Related Links


    Kiyoshi Mizuuchi, Ph.D.

    NIH Distinguished Investigator, Laboratory of Molecular BiologyGenetic Mechanisms Section
    • Biomedical Engineering/Biophysics/Physics
    • Cancer Biology
    • Microbiology/Infectious Diseases (non-viral)
    • Molecular Biology/Biochemistry
    • Systems Biology


    A selection of recent and significant publications can be viewed below.

    Hwang LC, Vecchiarelli AG, Han YW, Mizuuchi M, Harada Y, Funnell BE, Mizuuchi K. ParA-mediated plasmid partition driven by protein pattern self-organization. EMBO J. 2013 May 2; 32:1238-49. [Full Text/Abstract]
    Vecchiarelli AG, Hwang LC, Mizuuchi K. Cell-free study of F plasmid partition provides evidence for cargo transport by a diffusion-ratchet mechanism. Proc. Natl. Acad. Sci. U.S.A. 2013 Apr 9; 110:E1390-7. [Full Text/Abstract]
    Vecchiarelli AG, Mizuuchi K, Funnell BE. Surfing biological surfaces: exploiting the nucleoid for partition and transport in bacteria. Mol. Microbiol. 2012 Nov; 86:513-23. [Full Text/Abstract]
    Vecchiarelli AG, Han YW, Tan X, Mizuuchi M, Ghirlando R, Biertümpfel C, Funnell BE, Mizuuchi K. ATP control of dynamic P1 ParA-DNA interactions: a key role for the nucleoid in plasmid partition. Mol. Microbiol. 2010 Oct; 78:78-91. [Full Text/Abstract]
    Han YW, Mizuuchi K. Phage Mu transposition immunity: protein pattern formation along DNA by a diffusion-ratchet mechanism. Mol. Cell. 2010 Jul 9; 39:48-58. [Full Text/Abstract]
    Ivanov V, Mizuuchi K. Multiple modes of interconverting dynamic pattern formation by bacterial cell division proteins. Proc. Natl. Acad. Sci. U.S.A. 2010 May 4; 107:8071-8. [Full Text/Abstract]
    Skoko D, Li M, Huang Y, Mizuuchi M, Cai M, Bradley CM, Pease PJ, Xiao B, Marko JF, Craigie R, Mizuuchi K. Barrier-to-autointegration factor (BAF) condenses DNA by looping. Proc. Natl. Acad. Sci. U.S.A. 2009 Sep 29; 106:16610-5. [Full Text/Abstract]
    Greene EC, Mizuuchi K. Target immunity during Mu DNA transposition. Transpososome assembly and DNA looping enhance MuA-mediated disassembly of the MuB target complex. Mol. Cell. 2002 Dec; 10:1367-78. [Full Text/Abstract]
    Yanagihara K, Mizuuchi K. Mismatch-targeted transposition of Mu: a new strategy to map genetic polymorphism. Proc. Natl. Acad. Sci. U.S.A. 2002 Aug 20; 99:11317-21. [Full Text/Abstract]
    Greene EC, Mizuuchi K. Direct observation of single MuB polymers: evidence for a DNA-dependent conformational change for generating an active target complex. Mol. Cell. 2002 May; 9:1079-89. [Full Text/Abstract]