U.S. Department of Health and Human Services
Kiyoshi Mizuuchi
 

 Contact Info

 
Tel: 301-496-8154
Email: kmizu@helix.nih.gov
 

 Select Experience

 
  • D.S. (Ph.D.)Osaka University1972
  • M.S.Osaka University1969
  • B.S.Osaka University1967
 

 Related Links

 

    Kiyoshi Mizuuchi, Ph.D.

    NIH Distinguished Investigator, Laboratory of Molecular BiologyGenetic Mechanisms Section
    Specialties
    • Biomedical Engineering/Biophysics/Physics
    • Cancer Biology
    • Microbiology/Infectious Diseases (non-viral)
    • Molecular Biology/Biochemistry
    • Systems Biology

    Research in Plain Language

    Deoxyribonucleic acid (DNA) is a very important molecule. DNA encodes biological instructions for all living things. These instructions make each species and individual unique. DNA provides the instructions for biological processes. These include development, survival, and reproduction. DNA makes up an organism’s genome. The genome contains an organism’s hereditary information. Adults pass their genome on to their offspring.

    Our lab studies how certain DNA segments rearrange. Such changes affect health.  Researchers have learned about DNA segments called transposons. They can change positions within a genome or among separate genomes.  Transposons can reduce medications’ ability to fight disease-carrying bacteria.  We study these changes in the Mu virus. Our lab examines the molecular processes that drive DNA rearrangements. We also study how bacterial cells distribute their genetic blueprints.