My laboratory focuses on human energy metabolism as it relates to health and disease. We have developed several whole-room indirect calorimeters, also called respiration or metabolic chambers, which we use to measure the rate of energy expenditure at the minute-by-minute level and substrate oxidation for several hours or for several days. We can also simultaneously measure movement and physiological parameters in this well-controlled environment to study the impacts of physical activities, diets, medications, and environmental temperatures on energy metabolism, heart rate, and hormonal responses. We are also developing new technologies for measuring body composition and physical activity in humans.
The metabolic responses to common environmental stimuli, as simple as room temperature, and how individuals are different, are not well understood.