U.S. Department of Health and Human Services
Kong Chen
 

 Contact Info

 
Tel: 301-451-1636
Email: chenkong@niddk.nih.gov
 

 Select Experience

 
  • M.S.Vanderbilt University2002
  • Ph.D.Vanderbilt University1997
 

 Related Links

 
Specialties
  • Biomedical Engineering/Biophysics/Physics
  • Clinical Research
  • Epidemiology/Population Sciences
  • Physiology and Energy Metabolism

​Publications

A selection of recent and significant publications can be viewed below.

Publications
Geil CR, Hayes DM, McClain JA, Liput DJ, Marshall SA, Chen KY, Nixon K. Alcohol and adult hippocampal neurogenesis: promiscuous drug, wanton effects. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Oct 3; 54 (2014 Oct 3; 54):103-13. [Full Text/Abstract]
Malaguarnera R, Chen KY, Kim TY, Dominguez JM, Voza F, Ouyang B, Vundavalli SK, Knauf JA, Fagin JA. Switch in Signaling Control of mTORC1 Activity After Oncoprotein Expression in Thyroid Cancer Cell Lines. J Clin Endocrinol Metab. 2014 Jul 16; 99 (2014 Jul 16; 99; 10):E1976-E1987. [Full Text/Abstract]
Chen KY, Cheng CJ, Yen CM, Tang P, Wang LC. Comparative studies on the proteomic expression patterns in the third- and fifth-stage larvae of Angiostrongylus cantonensis. Parasitol Res. 2014 Jul 16; 113 (113; 2014 Jul 16; 10):3591-600. [Full Text/Abstract]
Hung YN, Yang SY, Huang MC, Lung FW, Lin SK, Chen KY, Kuo CJ, Chen YY. Cancer incidence in people with affective disorder: nationwide cohort study in Taiwan, 1997-2010. Br J Psychiatry. 2014 Jun 26; 205 (205; 2014 Jun 26; 3):183-8. [Full Text/Abstract]
Lee JH, Lin YL, Hsu WH, Chen HY, Chang YC, Yu CJ, Shih JY, Lin CC, Chen KY, Ho CC, Laio WY, Yang PC, Yang JC. Bcl-2-like protein 11 deletion polymorphism predicts survival in advanced non-small-cell lung cancer. J Thorac Oncol. 2014 Sep; 9 (9; 2014 Sep):1385-92. [Full Text/Abstract]
Chao HR, Lin DY, Chen KY, Gou YY, Chiou TH, Lee WJ, Chen SJ, Wang LC. Atmospheric concentrations of persistent organic pollutants over the Pacific Ocean near southern Taiwan and the northern Philippines. Sci Total Environ. 2014 Sep 1; 491-492 (491-492; 2014 Sep 1):51-9. [Full Text/Abstract]
Liu DJ, Hammer D, Komlos D, Chen KY, Firestein BL, Liu AY. SIRT1 Knockdown Promotes Neural Differentiation and Attenuates the Heat Shock Response. J Cell Physiol. 2014 Sep; 229 (229; 9; 2014 Sep):1224-35. [Full Text/Abstract]
Chen KY, Wezenberg SJ, Carroll GT, London G, Kistemaker JC, Pijper TC, Feringa BL. Tetrapodal molecular switches and motors: synthesis and photochemistry. J Org Chem. 2014 Aug 1; 79 (15; 2014 Aug 1; 79):7032-40. [Full Text/Abstract]
Wang Z, Zhu B, Zhang M, Parikh H, Jia J, Chung CC, Sampson JN, Hoskins JW, Hutchinson A, Burdette L, Ibrahim A, Hautman C, Raj PS, Abnet CC, Adjei AA, Ahlbom A, Albanes D, Allen NE, Ambrosone CB, Aldrich M, Amiano P, Amos C, Andersson U, Andriole G Jr, Andrulis IL, Arici C, Arslan AA, Austin MA, Baris D, Barkauskas DA, Bassig BA, Beane Freeman LE, Berg CD, Berndt SI, Bertazzi PA, Biritwum RB, Black A, Blot W, Boeing H, Boffetta P, Bolton K, Boutron-Ruault MC, Bracci PM, Brennan P, Brinton LA, Brotzman M, Bueno-de-Mesquita HB, Buring JE, Butler MA, Cai Q, Cancel-Tassin G, Canzian F, Cao G, Caporaso NE, Carrato A, Carreon T, Carta A, Chang GC, Chang IS, Chang-Claude J, Che X, Chen CJ, Chen CY, Chen CH, Chen C, Chen KY, Chen YM, Chokkalingam AP, Chu LW, Clavel-Chapelon F, Colditz GA, Colt JS, Conti D, Cook MB, Cortessis VK, Crawford ED, Cussenot O, Davis FG, De Vivo I, Deng X, Ding T, Dinney CP, Di Stefano AL, Diver WR, Duell EJ, Elena JW, Fan JH, Feigelson HS, Feychting M, Figueroa JD, Flanagan AM, Fraumeni JF Jr, Freedman ND, Fridley BL, Fuchs CS, Gago-Dominguez M, Gallinger S, Gao YT, Gapstur SM, Garcia-Closas M, Garcia-Closas R, Gastier-Foster JM, Gaziano JM, Gerhard DS, Giffen CA, Giles GG, Gillanders EM, Giovannucci EL, Goggins M, Gokgoz N, Goldstein AM, Gonzalez C, Gorlick R, Greene MH, Gross M, Grossman HB, Grubb R 3rd, Gu J, Guan P, Haiman CA, Hallmans G, Hankinson SE, Harris CC, Hartge P, Hattinger C, Hayes RB, He Q, Helman L, Henderson BE, Henriksson R, Hoffman-Bolton J, Hohensee C, Holly EA, Hong YC, Hoover RN, Hosgood HD 3rd, Hsiao CF, Hsing AW, Hsiung CA, Hu N, Hu W, Hu Z, Huang MS, Hunter DJ, Inskip PD, Ito H, Jacobs EJ, Jacobs KB, Jenab M, Ji BT, Johansen C, Johansson M, Johnson A, Kaaks R, Kamat AM, Kamineni A, Karagas M, Khanna C, Khaw KT, Kim C, Kim IS, Kim JH, Kim YH, Kim YC, Kim YT, Kang CH, Jung YJ, Kitahara CM, Klein AP, Klein R, Kogevinas M, Koh WP, Kohno T, Kolonel LN, Kooperberg C, Kratz CP, Krogh V, Kunitoh H, Kurtz RC, Kurucu N, Lan Q, Lathrop M, Lau CC, Lecanda F, Lee KM, Lee MP, Le Marchand L, Lerner SP, Li D, Liao LM, Lim WY, Lin D, Lin J, Lindstrom S, Linet MS, Lissowska J, Liu J, Ljungberg B, Lloreta J, Lu D, Ma J, Malats N, Mannisto S, Marina N, Mastrangelo G, Matsuo K, McGlynn KA, McKean-Cowdin R, McNeill LH, McWilliams RR, Melin BS, Meltzer PS, Mensah JE, Miao X, Michaud DS, Mondul AM, Moore LE, Muir K, Niwa S, Olson SH, Orr N, Panico S, Park JY, Patel AV, Patino-Garcia A, Pavanello S, Peeters PH, Peplonska B, Peters U, Petersen GM, Picci P, Pike MC, Porru S, Prescott J, Pu X, Purdue MP, Qiao YL, Rajaraman P, Riboli E, Risch HA, Rodabough RJ, Rothman N, Ruder AM, Ryu JS, Sanson M, Schned A, Schumacher FR, Schwartz AG, Schwartz KL, Schwenn M, Scotlandi K, Seow A, Serra C, Serra M, Sesso HD, Severi G, Shen H, Shen M, Shete S, Shiraishi K, Shu XO, Siddiq A, Sierrasesumaga L, Sierri S, Loon Sihoe AD, Silverman DT, Simon M, Southey MC, Spector L, Spitz M, Stampfer M, Stattin P, Stern MC, Stevens VL, Stolzenberg-Solomon RZ, Stram DO, Strom SS, Su WC, Sund M, Sung SW, Swerdlow A, Tan W, Tanaka H, Tang W, Tang ZZ, Tardon A, Tay E, Taylor PR, Tettey Y, Thomas DM, Tirabosco R, Tjonneland A, Tobias GS, Toro JR, Travis RC, Trichopoulos D, Troisi R, Truelove A, Tsai YH, Tucker MA, Tumino R, Van Den Berg D, Van Den Eeden SK, Vermeulen R, Vineis P, Visvanathan K, Vogel U, Wang C, Wang C, Wang J, Wang SS, Weiderpass E, Weinstein SJ, Wentzensen N, Wheeler W, White E, Wiencke JK, Wolk A, Wolpin BM, Wong MP, Wrensch M, Wu C, Wu T, Wu X, Wu YL, Wunder JS, Xiang YB, Xu J, Yang HP, Yang PC, Yatabe Y, Ye Y, Yeboah ED, Yin Z, Ying C, Yu CJ, Yu K, Yuan JM, Zanetti KA, Zeleniuch-Jacquotte A, Zheng W, Zhou B, Mirabello L, Savage SA, Kraft P, Chanock SJ, Yeager M, Landi MT, Shi J, Chatterjee N, Amundadottir LT. Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. Hum Mol Genet. 2014 Jul 15; 23 (2014 Jul 15; 23; 24):6616-33. [Full Text/Abstract]
Chen KY, Chen CC, Tseng YL, Chang YC, Chang MC. GCIP functions as a tumor suppressor in non-small cell lung cancer by suppressing Id1-mediated tumor promotion. Oncotarget. 2014 Jul 15; 5 (2014 Jul 15; 13; 5):5017-28. [Full Text/Abstract]
Chen JH, Chen KY, Hueng DY, Jin JS. Secondary pulmonary conventional chordoma arising from primary sarcomatoid chordoma of the sacrum: A case report. Oncol Lett. 2014 Jul; 8 (8; 2014 Jul; 1):208-210. [Full Text/Abstract]
Martin KR, Koster A, Murphy RA, Van Domelen DR, Hung MY, Brychta RJ, Chen KY, Harris TB. Changes in Daily Activity Patterns with Age in U.S. Men and Women: National Health and Nutrition Examination Survey 2003-04 and 2005-06. J Am Geriatr Soc. 2014 Jul; 62 (7; 62; 2014 Jul):1263-71. [Full Text/Abstract]
van der Berg JD, Bosma H, Caserotti P, Eiriksdottir G, Arnardottir NY, Martin KR, Brychta RJ, Chen KY, Sveinsson T, Johannsson E, Launer LJ, Gudnason V, Jonsson PV, Stehouwer CD, Harris TB, Koster A. Midlife Determinants Associated with Sedentary Behavior in Old Age. Med Sci Sports Exerc. 2014 Jul; 46 (46; 7; 2014 Jul):1359-65. [Full Text/Abstract]
Troiano RP, McClain JJ, Brychta RJ, Chen KY. Evolution of accelerometer methods for physical activity research. Br J Sports Med. 2014 Jul; (2014 Jul). [Full Text/Abstract]
Lee P, Smith S, Linderman J, Courville AB, Brychta RJ, Dieckmann W, Werner CD, Chen KY, Celi FS. Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans. Diabetes. 2014 Jun 22; 63 (2014 Jun 22; 63; 11):3686-98. [Full Text/Abstract]
Li YJ, Hyun MH, Rha SW, Chen KY, Jin Z, Dang Q, Park CM, Lee JE, Park JY, Choi CU, Na JO, Lim HE, Kim JW, Kim EJ, Park CG, Seo HS, Oh DJ. Diabetes Mellitus is Not a Risk Factor for Coronary Artery Spasm as Assessed by an Intracoronary Acetylcholine Provocation Test: Angiographic and Clinical Characteristics of 986 Patients. J Invasive Cardiol. 2014 Jun; 26 (6; 26; 2014 Jun):234-239. [Full Text/Abstract]
Chang SH, Chen KY, Wang LC. Identification and characterization of an asparaginyl endopeptidase from Angiostrongylus cantonensis. Parasitol Res. 2014 Jun; 113 (113; 6; 2014 Jun):2143-52. [Full Text/Abstract]
Campfield B, Chen K, Kolls JK. Vaccine approaches for multidrug resistant Gram negative infections. Curr Opin Immunol. 2014 Jun; 28C (28C; 2014 Jun):84-89. [Full Text/Abstract]
Lin WC, Fang SK, Hu JW, Tsai HY, Chen KY. Ratiometric Fluorescent/Colorimetric Cyanide-Selective Sensor Based on Excited-State Intramolecular Charge Transfer -Excited-State Intramolecular Proton Transfer Switching. Anal Chem. 2014 May 20; 86 (86; 2014 May 20; 10):4648-52. [Full Text/Abstract]
Chen KY, Sun J, Salvo JS, Baker D, Barth P. High-resolution modeling of transmembrane helical protein structures from distant homologues. PLoS Comput Biol. 2014 May; 10 (2014 May; 10; 5):e1003636. [Full Text/Abstract]
Wang HN, Chen HD, Chen KY, Xiao JF, He K, Xiang GA, Xie X. Highly expressed MT-ND3 positively associated with histological severity of hepatic steatosis. APMIS. 2014 May; 122 (122; 2014 May; 5):443-51. [Full Text/Abstract]
Zhang M, Wu JF, Chen WJ, Tang SL, Mo ZC, Tang YY, Li Y, Wang JL, Liu XY, Peng J, Chen K, He PP, Lv YC, Ouyang XP, Yao F, Tang DP, Cayabyab FS, Zhang DW, Zheng XL, Tian GP, Tang CK. MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages. Atherosclerosis. 2014 May; 234 (2014 May; 234; 1):54-64. [Full Text/Abstract]
Chen KY, Chen L, Mao J. Buprenorphine-naloxone therapy in pain management. Anesthesiology. 2014 May; 120 (120; 2014 May; 5):1262-74. [Full Text/Abstract]
Chang HM, Liu CH, Hsu WM, Chen LY, Wang HP, Wu TH, Chen KY, Ho WH, Liao WC. Proliferative effects of melatonin on Schwann cells: implication for nerve regeneration following peripheral nerve injury. J Pineal Res. 2014 Apr; 56 (56; 3; 2014 Apr):322-32. [Full Text/Abstract]
Choi SM, McAleer JP, Trevejo-Nunez G, Pociask DA, Armentrout RA, Chen K, Kolls JK. Acute Alcohol Intoxication Impairs Methicillin-Resistant Staphylococcus aureus Clearance in the Lung by Impeding Epithelial Production of Reg3γ. Infect Immun. 2014 Apr; 82 (82; 4; 2014 Apr):1402-7. [Full Text/Abstract]
Van Domelen DR, Caserotti P, Brychta RJ, Harris TB, Patel KV, Chen KY, Arnardottir NY, Eirikdottir G, Launer LJ, Gudnason V, Sveinsson T, Jóhannsson E, Koster A. Is there a sex difference in accelerometer counts during walking in older adults?. J Phys Act Health. 11 (3; 11):626-37. [Full Text/Abstract]
Chen KY, Harniss M, Patel S, Johnson K. Implementing technology-based embedded assessment in the home and community life of individuals aging with disabilities: a participatory research and development study. Disabil Rehabil Assist Technol. 2014 Mar; 9 (2014 Mar; 2; 9):112-20. [Full Text/Abstract]
Tang WR, Chen KY, Hsu SH, Juang YY, Chiu SC, Hsiao SC, Fujimori M, Fang CK. Effectiveness of Japanese SHARE model in improving Taiwanese healthcare personnel's preference for cancer truth telling. Psychooncology. 2014 Mar; 23 (2014 Mar; 23; 3):259-65. [Full Text/Abstract]
Chen KY, Ivashenko O, Carroll GT, Robertus J, Kistemaker JC, London G, Browne WR, Rudolf P, Feringa BL. Control of Surface Wettability Using Tripodal Light-Activated Molecular Motors. J Am Chem Soc. 2014 Feb 26; 136 (2014 Feb 26; 8; 136):3219-24. [Full Text/Abstract]
Lee P, Linderman JD, Smith S, Brychta RJ, Wang J, Idelson C, Perron RM, Werner CD, Phan GQ, Kammula US, Kebebew E, Pacak K, Chen KY, Celi FS. Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans. Cell Metab. 2014 Feb 4; 19 (19; 2; 2014 Feb 4):302-9. [Full Text/Abstract]
Tseng MC, Yao G, Hu FC, Chen KY, Fang D. Psychometric properties of the eating disorder inventory in clinical and nonclinical populations in Taiwan. Assessment. 2014 Feb; 21 (2014 Feb; 21; 1):50-9. [Full Text/Abstract]
Hsieh YP, Hofmann M, Chang KW, Jhu JG, Li YY, Chen KY, Yang CC, Chang WS, Chen LC. Complete corrosion inhibition through graphene defect passivation. ACS Nano. 2014 Jan 28; 8 (8; 2014 Jan 28; 1):443-8. [Full Text/Abstract]
Gopal R, Rangel-Moreno J, Fallert Junecko BA, Mallon DJ, Chen K, Pociask DA, Connell TD, Reinhart TA, Alcorn JF, Ross TM, Kolls JK, Khader SA. Mucosal pre-exposure to Th17-inducing adjuvants exacerbates pathology after influenza infection. Am J Pathol. 2014 Jan; 184 (2014 Jan; 184; 1):55-63. [Full Text/Abstract]
Tsai HY, Chang CW, Chen KY. 1,6- and 1,7-regioisomers of asymmetric and symmetric perylene bisimides: synthesis, characterization and optical properties. Molecules. 2013 Dec 27; 19 (19; 2013 Dec 27; 1):327-41. [Full Text/Abstract]
Kao CC, Wang RH, Ying JC, Lin YH, Chang FY, Chen KY. Psychometric analysis of the Short-Form Chinese Health and Safety Executive's Management Standards Indicator Tool among nurses in Taiwan. J Health Psychol. 2013 Dec 26; (2013 Dec 26). [Full Text/Abstract]
Carnie A, Lin J, Aicher B, Leon B, Courville AB, Sebring NG, de Jesus J, Dellavalle DM, Fitzpatrick BD, Zalos G, Powell-Wiley TM, Chen KY, Cannon RO 3rd. Randomized trial of nutrition education added to internet-based information and exercise at the work place for weight loss in a racially diverse population of overweight women. Nutr Diabetes. 2013 Dec 23; 3 (2013 Dec 23; 3):e98. [Full Text/Abstract]
Chen KY, Janz KF, Zhu W, Brychta RJ. Redefining the roles of sensors in objective physical activity monitoring. Med Sci Sports Exerc. 2012 Jan; 44 (1 Suppl 1; 44; 2012 Jan):S13-23. [Full Text/Abstract]
Celi FS, Brychta RJ, Linderman JD, Butler PW, Alberobello AT, Smith S, Courville AB, Lai EW, Costello R, Skarulis MC, Csako G, Remaley A, Pacak K, Chen KY. Minimal changes in environmental temperature result in a significant increase in energy expenditure and changes in the hormonal homeostasis in healthy adults. Eur J Endocrinol. 2010 Dec; 163 (6; 2010 Dec; 163):863-72. [Full Text/Abstract]
Tamboli RA, Hossain HA, Marks PA, Eckhauser AW, Rathmacher JA, Phillips SE, Buchowski MS, Chen KY, Abumrad NN. Body composition and energy metabolism following Roux-en-Y gastric bypass surgery. Obesity (Silver Spring). 2010 Sep; 18 (2010 Sep; 9; 18):1718-24. [Full Text/Abstract]
Rothney MP, Brychta RJ, Meade NN, Chen KY, Buchowski MS. Validation of the ActiGraph two-regression model for predicting energy expenditure. Med Sci Sports Exerc. 2010 Sep; 42 (42; 2010 Sep; 9):1785-92. [Full Text/Abstract]
Brychta R, Wohlers E, Moon J, Chen K. Energy expenditure: measurement of human metabolism. IEEE Eng Med Biol Mag. 2010 Jan-Feb; 29 (29; 1; 2010 Jan-Feb):42-7. [Full Text/Abstract]
Rothney MP, Brychta RJ, Schaefer EV, Chen KY, Skarulis MC. Body composition measured by dual-energy X-ray absorptiometry half-body scans in obese adults. Obesity (Silver Spring). 2009 Jun; 17 (6; 17; 2009 Jun):1281-6. [Full Text/Abstract]
Brychta RJ, Rothney MP, Skarulis MC, Chen KY. Optimizing energy expenditure detection in human metabolic chambers. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009 (2009):6864-8. [Full Text/Abstract]
Rothney MP, Schaefer EV, Neumann MM, Choi L, Chen KY. Validity of physical activity intensity predictions by ActiGraph, Actical, and RT3 accelerometers. Obesity (Silver Spring). 2008 Aug; 16 (8; 16; 2008 Aug):1946-52. [Full Text/Abstract]
Matthews CE, Chen KY, Freedson PS, Buchowski MS, Beech BM, Pate RR, Troiano RP. Amount of time spent in sedentary behaviors in the United States, 2003-2004. Am J Epidemiol. 2008 Apr 1; 167 (7; 2008 Apr 1; 167):875-81. [Full Text/Abstract]
Rothney MP, Neumann M, Béziat A, Chen KY. An artificial neural network model of energy expenditure using nonintegrated acceleration signals. J Appl Physiol (1985). 2007 Oct; 103 (2007 Oct; 4; 103):1419-27. [Full Text/Abstract]
Shibao C, Gamboa A, Diedrich A, Ertl AC, Chen KY, Byrne DW, Farley G, Paranjape SY, Davis SN, Biaggioni I. Autonomic contribution to blood pressure and metabolism in obesity. Hypertension. 2007 Jan; 49 (49; 2007 Jan; 1):27-33. [Full Text/Abstract]
Chen KY, Bassett DR Jr. The technology of accelerometry-based activity monitors: current and future. Med Sci Sports Exerc. 2005 Nov; 37 (11 Suppl; 2005 Nov; 37):S490-500. [Full Text/Abstract]