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Enlaces a nuestra información en español sobre la diabetes, enfermedades digestivas, enfermedades renales, control de peso, enfermedades urológicas, enfermedades endocrinas y metabólicas, y enfermedades hematológicas
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A guide to animal models which have been used to study molecular mechanisms of Mammary Gland Development, Physiology and Tumorigenesis.
Stat 5a Knockout: Stat5a deficiency results in the loss of prolactin-dependent mammary gland development and lactogenesis.
Prolactin induces mammary gland development and …
Floxed Bcl-x: Conditional knockout of pro-survival Bcl-x in primordial germ cells was used to study the balance between pro-aptoptotic Bax during embryogenesis.
Bcl-x is a pro-survival …
Conditional knockout of Stat5a and Stat5b: Combined deletion of conserved Stat5a and Stat5b in mammary epithelium at different times during pregnancy reveal multiple distinct functions.
Cre-recombinase under the control of mouse mammary tumor virus long terminal repeat (MMTV) was expressed in the salivary gland and mammary epithelial cells of adult mice, and induced recombination …
Cre-recombinase under the control of the whey acidic acid protein was only detected in alveolar epithelial epithelial cells of mammary tissue during lactation, and transcription occurred at …
Selective inactivation of Stat 1 in mammary cells indicates that its effect as a tumor suppressor in breast is direct.
STAT1 is considered a tumor suppressor, but it is not …
Open studies conducted by NIDDK Principal Investigators appear below that are currently recruiting, not yet recruiting, or available for expanded access.