U.S. Department of Health and Human Services
Marc Reitman

 Contact Info

Tel: +1 301 496 6442
Email: marc.reitman@nih.gov

 Training and Experience

M.D., Ph.D., Washington University, 1983

B.S., Massachusetts Institute of Technology, 1977

Branch Chief, NIDDK, NIH, 2011-present

Senior Investigator, NIDDK, NIH, 2011-present

Director, Clinical Research, Merck Research Laboratories, 2002-2011

Director, Obesity and Metabolic Research, Merck Research Laboratories, 2002-2011

Senior Investigator, NIDDK, NIH, 1991-2002

Investigator, NIDDK, NIH, 1991-2002

Fellowship, NIDDK, NIH, 1989-1991

Fellowship, NIDDK, NIH, 1986-1989

Residency, Columbia-Presbyterian Hospital, 1983-1986

 Related Links


    Specialties: Molecular Biology/Biochemistry, Molecular Pharmacology/Toxicology, Neuroscience/Neurophysiology/Neurodevelopment, Clinical Research, Genetics/Genomics

    Research Summary

    Research Goal

    Obesity has reached pandemic proportions and treatment is rarely successful for the long term.  We believe that by elucidating the underlying physiology, novel and effective anti-obesity therapies will be discovered.  Effective obesity treatment will also stem the epidemic of type 2 diabetes mellitus.

    Current Research

    I am broadly interested in a mechanistic and translational understanding of diabetes, energy homeostasis, and obesity.  My particular interests include studying mouse genetics and pharmacology, using mouse models to understand metabolic rate regulation, body temperature regulation and the role of BRS-3 (bombesin receptor subtype-3), and exploring drug treatments for obesity.  One current project involves dissecting how BRS-3 regulates metabolic rate, body temperature, and blood pressure.  Another project explores how to improve the use of mice to evaluate candidate treatments for human obesity.  A third interest is the role of brown adipose tissue and uncoupling in mouse and human thermal biology and body weight regulation.​

    Applying our Research

    By studying the mechanisms involved in energy homeostasis, we should gain knowledge that will lead to advancements in the treatment of diabetes and obesity.