Our group studies the part of a person’s body that controls how many calories their body uses during the day compared to how many calories that person eats. We are trying to understand why some people may be able to remain thin even after days of overeating while other people may gain weight more easily. We are also trying to understand if a person is more likely to gain weight if he or she eats carbohydrates, protein, or fat when he or she overeats.
We have a second study that focuses on weight loss and the medication exenatide. We are studying the different ways this medication can contribute to weight loss and which people are more likely to lose weight while dieting. For example, are people who use more calories during the day, or those who are less stressed, or those who have certain high levels of hormones in their body more likely to lose weight?