U.S. Department of Health and Human Services
Peter Walter
 

 Contact Info

 
Tel: 301-443-7307
Email: walterpj@mail.nih.gov
 

 Select Experience

 
  • Staff ScientistNIDDK, NIH2008-present
  • Principal Research ScientistU.S. Centers for Disease Control and Prevention2005-2008
  • Ph.D.Duquesne University1996
  • M.S.Virginia Tech1987
 

 Related Links

 

    Peter Walter, Ph.D.

    Director, Clinical Mass Spectometry Core
    Specialties
    • Chemistry/Chemical Biology

    ​Publications

    A selection of recent and significant publications can be viewed below.

    Publications
    Schuck S, Gallagher CM, Walter P. ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery. J Cell Sci. 2014 Jul 22; 127 (127; Pt 18; 2014 Jul 22):4078-88. [Full Text/Abstract]
    van den Hurk J, Dippel AC, Cho DY, Straquadine J, Breuer U, Walter P, Waser R, Valov I. Physical origins and suppression of Ag dissolution in GeS(x)-based ECM cells. Phys Chem Chem Phys. 2014 Aug 6; 16 (16; 2014 Aug 6; 34):18217-25. [Full Text/Abstract]
    Fuest M, Mamas N, Walter P, Plange N. Tonometry in corneal edema after cataract surgery: rebound versus goldmann applanation tonometry. Curr Eye Res. 2014 Sep; 39 (39; 9; 2014 Sep):902-7. [Full Text/Abstract]
    Di Prisco GV, Huang W, Buffington SA, Hsu CC, Bonnen PE, Placzek AN, Sidrauski C, Krnjević K, Kaufman RJ, Walter P, Costa-Mattioli M. Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α. Nat Neurosci. 2014 Aug; 17 (8; 17; 2014 Aug):1073-82. [Full Text/Abstract]
    Fuest M, Plange N, Jamali S, Schwarzer H, Roessler G, Walter P, Mazinani B. The effect of cataract surgery on blue-yellow and standard-pattern visual-evoked potentials. Graefes Arch Clin Exp Ophthalmol. 2014 Jul 17; 252 (2014 Jul 17; 252; 11):1831-7. [Full Text/Abstract]
    Noriega TR, Tsai A, Elvekrog MM, Petrov A, Neher SB, Chen J, Bradshaw N, Puglisi JD, Walter P. Signal Recognition Particle-Ribosome Binding Is Sensitive To Nascent-Chain Length. J Biol Chem. 2014 Jul 11; 289 (28; 2014 Jul 11; 289):19294-305. [Full Text/Abstract]
    Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science. 2014 Jul 4; 345 (6192; 2014 Jul 4; 345):98-101. [Full Text/Abstract]
    Fuest M, Kotliar K, Walter P, Plange N. Monitoring intraocular pressure changes after intravitreal Ranibizumab injection using rebound tonometry. Ophthalmic Physiol Opt. 2014 Jul; 34 (4; 2014 Jul; 34):438-44. [Full Text/Abstract]
    Okreglak V, Walter P. The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins. Proc Natl Acad Sci U S A. 2014 Jun 3; 111 (111; 22; 2014 Jun 3):8019-24. [Full Text/Abstract]
    Rösch S, Johnen S, Mazinani B, Müller F, Pfarrer C, Walter P. The effects of iodoacetic acid on the mouse retina. Graefes Arch Clin Exp Ophthalmol. 2014 May 15; (2014 May 15). [Full Text/Abstract]
    Fleckenstein M, Schmitz-Valckenberg S, Lindner M, Bezatis A, Becker E, Fimmers R, Holz FG, Fundus Autofluorescence in Age-Related Macular Degeneration Study Group. The "diffuse-trickling" fundus autofluorescence phenotype in geographic atrophy. Invest Ophthalmol Vis Sci. 55 (55; 5):2911-20. [Full Text/Abstract]
    Vaidya A, Borgonovi E, Taylor RS, Sahel JA, Rizzo S, Stanga PE, Kukreja A, Walter P. The cost-effectiveness of the Argus II retinal prosthesis in Retinitis Pigmentosa patients. BMC Ophthalmol. 2014 Apr 14; 14 (14; 2014 Apr 14; 1):49. [Full Text/Abstract]
    Chang YC, Khanal Lamichhane A, Garraffo HM, Walter PJ, Leerkes M, Kwon-Chung KJ. Molecular Mechanisms of Hypoxic Responses via Unique Roles of Ras1, Cdc24 and Ptp3 in a Human Fungal Pathogen Cryptococcus neoformans. PLoS Genet. 2014 Apr; 10 (4; 10; 2014 Apr):e1004292. [Full Text/Abstract]
    Rösch S, Johnen S, Mataruga A, Müller F, Pfarrer C, Walter P. Selective photoreceptor degeneration by intravitreal injection of N-methyl-N-nitrosourea. Invest Ophthalmol Vis Sci. 2014 Mar 20; 55 (2014 Mar 20; 55; 3):1711-23. [Full Text/Abstract]
    Saritas T, Koutsonas A, Walter P, Floege J, Krüger T. Management of intraocular hypertension during hemodialysis by intravenous glucose administration. Am J Kidney Dis. 2014 Mar; 63 (2014 Mar; 63; 3):500-2. [Full Text/Abstract]
    Waschkowski F, Hesse S, Rieck AC, Lohmann T, Brockmann C, Laube T, Bornfeld N, Thumann G, Walter P, Mokwa W, Johnen S, Roessler G. Development of very large electrode arrays for epiretinal stimulation (VLARS). Biomed Eng Online. 2014 Feb 6; 13 (2014 Feb 6; 13; 1):11. [Full Text/Abstract]
    Feltgen N, Walter P. Rhegmatogenous retinal detachment--an ophthalmologic emergency. Dtsch Arztebl Int. 2014 Jan 6; 111 (1-2; 111; 2014 Jan 6):12-21; quiz 22. [Full Text/Abstract]
    Yadav H, Lee JH, Lloyd J, Walter P, Rane SG. Beneficial metabolic effects of a probiotic via butyrate induced GLP-1 secretion. J Biol Chem. 2013 Aug 30; 288 (35; 288; 2013 Aug 30):25088-97. [Full Text/Abstract]
    Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife. 2013 May 28; 2 (2; 2013 May 28):e00498. [Full Text/Abstract]
    Cho JA, Lee AH, Platzer B, Cross BC, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host Microbe. 2013 May 15; 13 (2013 May 15; 13; 5):558-69. [Full Text/Abstract]
    Murley A, Lackner LL, Osman C, West M, Voeltz GK, Walter P, Nunnari J. ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast. Elife. 2013 May 14; 2 (2; 2013 May 14):e00422. [Full Text/Abstract]
    Feltgen N, Heimann H, Hoerauf H, Walter P, Hilgers RD, Heussen N, Writing group for the SPR study investigators*. Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR study): Risk assessment of anatomical outcome. SPR study report no. 7. Acta Ophthalmol. 2013 May; 91 (2013 May; 91; 3):282-7. [Full Text/Abstract]
    Walter P. Two structure papers, a call from Frankfurt airport, and how to escape from reviewer delays: an interview with Peter Walter by Miranda Robertson. BMC Biol. 2013 Apr 15; 11 (2013 Apr 15; 11):34. [Full Text/Abstract]
    Gardner BM, Pincus D, Gotthardt K, Gallagher CM, Walter P. Endoplasmic reticulum stress sensing in the unfolded protein response. Cold Spring Harb Perspect Biol. 2013 Mar 1; 5 (2013 Mar 1; 3; 5):a013169. [Full Text/Abstract]
    Koutsonas A, Plange N, Roessler GF, Walter P, Mazinani BA. A case of siderosis bulbi without a radiologically detectable foreign body. Can J Ophthalmol. 2013 Feb; 48 (48; 2013 Feb; 1):e9-e11. [Full Text/Abstract]
    Walter P, Metzger J, Thiel C, Helms V. Predicting where small molecules bind at protein-protein interfaces. PLoS One. 2013; 8 (8; 3; 2013):e58583. [Full Text/Abstract]
    Koutsonas A, Carstesen D, Henkel C, Walter P, Thumann G, Weinberger AW. Effects of coagulation on the autofluorescence pattern of ARPE-19 cells: an in vitro study. Ophthalmic Res. 2013; 49 (49; 1; 2013):11-9. [Full Text/Abstract]
    Fordyce PM, Pincus D, Kimmig P, Nelson CS, El-Samad H, Walter P, DeRisi JL. Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses. Proc Natl Acad Sci U S A. 2012 Nov 6; 109 (109; 2012 Nov 6; 45):E3084-93. [Full Text/Abstract]
    Kimmig P, Diaz M, Zheng J, Williams CC, Lang A, Aragón T, Li H, Walter P. The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. Elife. 2012 Oct 15; 1 (2012 Oct 15; 1):e00048. [Full Text/Abstract]
    Moreira KE, Schuck S, Schrul B, Fröhlich F, Moseley JB, Walther TC, Walter P. Seg1 controls eisosome assembly and shape. J Cell Biol. 2012 Aug 6; 198 (3; 198; 2012 Aug 6):405-20. [Full Text/Abstract]
    Pincus D, Walter P. A first line of defense against ER stress. J Cell Biol. 2012 Aug 6; 198 (3; 198; 2012 Aug 6):277-9. [Full Text/Abstract]
    Johnen S, Izsvák Z, Stöcker M, Harmening N, Salz AK, Walter P, Thumann G. Sleeping Beauty transposon-mediated transfection of retinal and iris pigment epithelial cells. Invest Ophthalmol Vis Sci. 2012 Jul 18; 53 (2012 Jul 18; 8; 53):4787-96. [Full Text/Abstract]
    Fischer S, Carstesen D, Klee D, Walter P, Weinberger AW. Surface-modified silicone foils for intraocular implantation. Graefes Arch Clin Exp Ophthalmol. 2012 Jun; 250 (2012 Jun; 6; 250):823-7. [Full Text/Abstract]
    Roessler GF, Dietlein TS, Plange N, Roepke AK, Dinslage S, Walter P, Mazinani BA. Accuracy of intraocular lens power calculation using partial coherence interferometry in patients with high myopia. Ophthalmic Physiol Opt. 2012 May; 32 (32; 2012 May; 3):228-33. [Full Text/Abstract]
    Schneider MV, Walter P, Blatter MC, Watson J, Brazas MD, Rother K, Budd A, Via A, van Gelder CW, Jacob J, Fernandes P, Nyrönen TH, De Las Rivas J, Blicher T, Jimenez RC, Loveland J, McDowall J, Jones P, Vaughan BW, Lopez R, Attwood TK, Brooksbank C. Bioinformatics Training Network (BTN): a community resource for bioinformatics trainers. Brief Bioinform. 2012 May; 13 (2012 May; 13; 3):383-9. [Full Text/Abstract]
    Menzel-Severing J, Siekmann U, Weinberger A, Roessler G, Walter P, Mazinani B. Early hyperbaric oxygen treatment for nonarteritic central retinal artery obstruction. Am J Ophthalmol. 2012 Mar; 153 (153; 2012 Mar; 3):454-459.e2. [Full Text/Abstract]
    Keserü M, Feucht M, Bornfeld N, Laube T, Walter P, Rössler G, Velikay-Parel M, Hornig R, Richard G. Acute electrical stimulation of the human retina with an epiretinal electrode array. Acta Ophthalmol. 2012 Feb; 90 (2012 Feb; 90; 1):e1-8. [Full Text/Abstract]
    Laube T, Brockmann C, Roessler G, Walter P, Krueger C, Goertz M, Klauke S, Bornfeld N. Development of surgical techniques for implantation of a wireless intraocular epiretinal retina implant in Göttingen minipigs. Graefes Arch Clin Exp Ophthalmol. 2012 Jan; 250 (250; 1; 2012 Jan):51-9. [Full Text/Abstract]
    Mazinani BA, Rajendram A, Walter P, Roessler GF. Does surgical experience have an effect on the success of retinal detachment surgery?. Retina. 2012 Jan; 32 (32; 1; 2012 Jan):32-7. [Full Text/Abstract]
    Korennykh A, Walter P. Structural basis of the unfolded protein response. Annu Rev Cell Dev Biol. 2012; 28 (28; 2012):251-77. [Full Text/Abstract]
    Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science. 2011 Nov 25; 334 (334; 6059; 2011 Nov 25):1081-6. [Full Text/Abstract]
    Schumacher C, Lohr A, Kaup M, Walter P, Roth J, Perez-Bouza A, Wagner N, Heiligenhaus A. Necrotizing sarcoid granulomatosis: ocular manifestation in 3 children of African origin. Arch Ophthalmol. 2011 Oct; 129 (2011 Oct; 10; 129):1370-2. [Full Text/Abstract]
    Gardner BM, Walter P. Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. Science. 2011 Sep 30; 333 (6051; 2011 Sep 30; 333):1891-4. [Full Text/Abstract]
    Castillo K, Rojas-Rivera D, Lisbona F, Caballero B, Nassif M, Court FA, Schuck S, Ibar C, Walter P, Sierralta J, Glavic A, Hetz C. BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J. 2011 Sep 16; 30 (2011 Sep 16; 30; 21):4465-78. [Full Text/Abstract]
    Joussen AM, Rizzo S, Kirchhof B, Schrage N, Li X, Lente C, Hilgers RD, HSO -Study Group. Heavy silicone oil versus standard silicone oil in as vitreous tamponade in inferior PVR (HSO Study): interim analysis. Acta Ophthalmol. 2011 Sep; 89 (2011 Sep; 6; 89):e483-9. [Full Text/Abstract]
    Roessler G, Laube T, Brockmann C, Kirschkamp T, Mazinani B, Menzel-Severing J, Bornfeld N, Walter P, EPIRET Group. Angiographic findings following tack fixation of a wireless epiretinal retina implant device in blind RP patients. Graefes Arch Clin Exp Ophthalmol. 2011 Sep; 249 (249; 2011 Sep; 9):1281-6. [Full Text/Abstract]
    Nguyen TX, Chandrasekar S, Neher S, Walter P, Shan SO. Concerted complex assembly and GTPase activation in the chloroplast signal recognition particle. Biochemistry. 2011 Aug 23; 50 (33; 50; 2011 Aug 23):7208-17. [Full Text/Abstract]
    Kornmann B, Osman C, Walter P. The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections. Proc Natl Acad Sci U S A. 2011 Aug 23; 108 (108; 2011 Aug 23; 34):14151-6. [Full Text/Abstract]
    Heussen N, Feltgen N, Walter P, Hoerauf H, Hilgers RD, Heimann H, SPR Study Group. Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR Study): predictive factors for functional outcome. Study report no. 6. Graefes Arch Clin Exp Ophthalmol. 2011 Aug; 249 (249; 8; 2011 Aug):1129-36. [Full Text/Abstract]
    Johnen S, Kazanskaya O, Armogan N, Stickelmann C, Stöcker M, Walter P, Thumann G. Endogenic regulation of proliferation and zinc transporters by pigment epithelial cells nonvirally transfected with PEDF. Invest Ophthalmol Vis Sci. 2011 Jul 23; 52 (8; 2011 Jul 23; 52):5400-7. [Full Text/Abstract]