U.S. Department of Health and Human Services
Rebecca Brown

 Contact Info

Tel: 301-594-0609
Email: brownrebecca@mail.nih.gov

 Select Experience

  • Assistant Clinical InvestigatorNIDDK, NIH2012–2015
  • Senior FellowNIDDK, NIH2008–2012
  • FellowNICHD, NIH2005–2008
  • ResidentRainbow Babies and Children’s Hospital2002–2005
  • Lasker Tenure Track InvestigatorNIDDK, NIH2015-present
  • M.H.Sc.Duke University2011
  • M.D.Mayo Medical School2002

 Related Links


Rebecca J. Brown, M.D., M.H.Sc., Lasker Tenure Track Investigator

Assistant Clinical Investigator, Clinical and Cellular Biology SectionDiabetes, Endocrinology, and Obesity Branch
  • Clinical Research


A selection of recent and significant publications can be viewed below.

Irving WL, Rupp D, McClure CP, Than LM, Titman A, Ball JK, Steinmann E, Bartenschlager R, Pietschmann T, Brown RJ. Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region. Antiviral Res. 2014 Jul 22; 110 (110; 2014 Jul 22):52-9. [Full Text/Abstract]
Joseph J, Shamburek RD, Cochran EK, Gorden P, Brown RJ. Lipid Regulation in Lipodystrophy Versus the Obesity-Associated Metabolic Syndrome: The Dissociation of HDL-C and Triglycerides. J Clin Endocrinol Metab. 2014 Jun 13; 99 (99; 2014 Jun 13; 9):E1676-80. [Full Text/Abstract]
Payne F, Lim K, Girousse A, Brown RJ, Kory N, Robbins A, Xue Y, Sleigh A, Cochran E, Adams C, Dev Borman A, Russel-Jones D, Gorden P, Semple RK, Saudek V, O'Rahilly S, Walther TC, Barroso I, Savage DB. Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease. Proc Natl Acad Sci U S A. 2014 Jun 17; 111 (111; 2014 Jun 17; 24):8901-6. [Full Text/Abstract]
Brown RJ, Yanovski JA. Estimation of insulin sensitivity in children: methods, measures and controversies. Pediatr Diabetes. 2014 May; 15 (2014 May; 15; 3):151-61. [Full Text/Abstract]
Muniyappa R, Brown RJ, Mari A, Joseph J, Warren MA, Cochran EK, Skarulis MC, Gorden P. Effects of Leptin Replacement Therapy on Pancreatic β-Cell Function in Patients With Lipodystrophy. Diabetes Care. 2014 Apr; 37 (37; 4; 2014 Apr):1101-7. [Full Text/Abstract]
Sarkar G, Alattar M, Brown RJ, Quon MJ, Harlan DM, Rother KI. Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes. Diabetes Care. 2014 Mar; 37 (2014 Mar; 37; 3):666-70. [Full Text/Abstract]
Nguyen TT, Jayadeva V, Cizza G, Brown RJ, Nandagopal R, Rodriguez LM, Rother KI. Challenging recruitment of youth with type 2 diabetes into clinical trials. J Adolesc Health. 2014 Mar; 54 (2014 Mar; 3; 54):247-54. [Full Text/Abstract]
Gorden P, Zadeh ES, Cochran E, Brown RJ. Syndromic insulin resistance: models for the therapeutic basis of the metabolic syndrome and other targets of insulin resistance. Endocr Pract. 2012 Sep-Oct; 18 (2012 Sep-Oct; 5; 18):763-71. [Full Text/Abstract]
Sylvetsky AC, Welsh JA, Brown RJ, Vos MB. Low-calorie sweetener consumption is increasing in the United States. Am J Clin Nutr. 2012 Sep; 96 (2012 Sep; 3; 96):640-6. [Full Text/Abstract]
Brown RJ, Rother KI. Non-nutritive sweeteners and their role in the gastrointestinal tract. J Clin Endocrinol Metab. 2012 Aug; 97 (2012 Aug; 8; 97):2597-605. [Full Text/Abstract]
Foreyt J, Kleinman R, Brown RJ, Lindstrom R. The use of low-calorie sweeteners by children: implications for weight management. J Nutr. 2012 Jun; 142 (2012 Jun; 6; 142):1155S-62S. [Full Text/Abstract]
Brown RJ, Walter M, Rother KI. Effects of diet soda on gut hormones in youths with diabetes. Diabetes Care. 2012 May; 35 (2012 May; 35; 5):959-64. [Full Text/Abstract]
Sylvetsky A, Rother KI, Brown R. Artificial sweetener use among children: epidemiology, recommendations, metabolic outcomes, and future directions. Pediatr Clin North Am. 2011 Dec; 58 (6; 58; 2011 Dec):1467-80, xi. [Full Text/Abstract]
Brown RJ, Wijewickrama RC, Harlan DM, Rother KI. Uncoupling intensive insulin therapy from weight gain and hypoglycemia in type 1 diabetes. Diabetes Technol Ther. 2011 Apr; 13 (2011 Apr; 4; 13):457-60. [Full Text/Abstract]
Brown RJ, Walter M, Rother KI. Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion. Diabetes Care. 2009 Dec; 32 (32; 12; 2009 Dec):2184-6. [Full Text/Abstract]
Rother KI, Brown RJ, Morales MM, Wright E, Duan Z, Campbell C, Hardin DS, Popovic J, McEvoy RC, Harlan DM, Orlander PR, Brod SA. Effect of ingested interferon-alpha on beta-cell function in children with new-onset type 1 diabetes. Diabetes Care. 2009 Jul; 32 (32; 7; 2009 Jul):1250-5. [Full Text/Abstract]
Brown RJ, Rother KI, Artman H, Mercurio MG, Wang R, Looney RJ, Cowen EW. Minocycline-induced drug hypersensitivity syndrome followed by multiple autoimmune sequelae. Arch Dermatol. 2009 Jan; 145 (145; 2009 Jan; 1):63-6. [Full Text/Abstract]
Brown RJ, Sinaii N, Rother KI. Too much glucagon, too little insulin: time course of pancreatic islet dysfunction in new-onset type 1 diabetes. Diabetes Care. 2008 Jul; 31 (7; 2008 Jul; 31):1403-4. [Full Text/Abstract]