U.S. Department of Health and Human Services
Richard Proia
 

 Contact Info

 
Tel: 301-496-4391
Email: proiar@mail.nih.gov
 

 Select Experience

 
  • Ph.D.University of Texas Southwestern Medical Center1980
  • B.S.Bates College1976
 

 Related Links

 

    Specialties
    • Cell Biology/Cell Signaling
    • Genetics/Genomics
    • Immunology
    • Molecular Biology/Biochemistry

    ​Resources

    Patents, materials, and other research resources appear below. Some resources may be available for use through Material Transfer Agreements (MTAs) or licensing agreements.

    Resource Name Description
    S1pr1 KO (S1pr1 tm1Rlp) Mouse (Mutant Mouse: S1pr1 (spingosine-1-phosphate receptor 1))

    A Sphingosine-1-phosphate Receptor-1 (S1pr1) knockout mouse

     

    Sphingosine-1-phosphate (S1P) is a potent bioactive lipid that activates a family of G-protein coupled receptors, … (Summary)

    S1pr2 KO Mouse (Mutant Mouse: S1pr2)

    A Spingosine-1-phosphate Receptor-2 (S1pr2) knockout mouse



    Sphingosine-1-phosphate (S1P), a sphingolipid metabolite, activates cell signaling by interacting with a family … (Summary)

    S1pr3 KO Mouse (Mutant Mouse: s1pr3)

    A Spingosine-1-phosphate Receptor-3 (S1pr3) knockout mouse

    Sphingosine-1-phosphate (S1P), a sphingolipid metabolite, activates cell signaling by interacting with a family … (Summary)

    Sphk1 KO Mouse (Mutant Mouse: Sphk1 (Sphingosine kinase 1))

    A Sphingosine kinase 1 (Sphk1) knockout mouse

     

    Sphingosine kinase 1 and 2 are enzymes that produce sphingosine-1-phosphate (S1P), a potent bioactive compound that activates … (Summary)

    S1pr1 LoxP (S1pr1 tm2Rlp) Mouse (Mutant Mouse: S1pr1)

    A conditional knockout mouse for S1pr1

     

    Sphingosine-1-phosphate (S1P) is a potent bioactive lipid that activates a family of G-protein coupled receptors, S1P1, S1P2, S1P3, … (Summary)

    Gaucher Gba-444 knock-in(Gba tm2Rlp) Mouse (Mutant Mouse: Gba (glucosidase, beta, acid).Knock-in P444L ±A456P mimic Gaucher disease.)

    Gba-444 knock-in mice carrying the milder L444P Gaucher disease mutation (Gba-L444P mice) and the severe Gaucher disease mutation (Gba-L444P A456P mice)

     

    Gba-L444P and Gba-L444P … (Summary)

    Sphk2 KO Mouse (Mutant Mouse: Sphk2 (Sphingosine Kinase 2))

    A knockout mouse for Sphingosine kinase 2 (Sphk2)

    Sphingosine kinase 1 and 2 are enzymes that produce sphingosine-1-phosphate (S1P), a potent bioactive compound that activates … (Summary)

    View Additional Research Resources

    Clinical Trials

    Open studies conducted by NIDDK Principal Investigators appear below that are currently recruiting, not yet recruiting, or available for expanded access.

    Study Title
    There are no associated clinical trials.
    Search for more clinical trials at ClinicalTrials.gov