U.S. Department of Health and Human Services
Robert Tycko
 

 Contact Info

 
Tel: 301-402-8272
Email: robertty@mail.nih.gov
 

 Select Experience

 
  • Senior InvestigatorLCP, NIDDK, NIH1994-present
  • Member of Technical Staff (Principal Investigator)Physical Chemistry Research Department, AT&T Bell Laboratories1986-1994
  • Postdoctoral ResearcherUniversity of Pennsylvania1984-1986
  • Ph.D.University of California at Berkeley1984
  • A.B.Princeton University1980
 

 Related Links

 

    Specialties
    • Biomedical Engineering/Biophysics/Physics

    ​Research Images

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    TitleDescriptionImage
    Electron microscope images of amyloid fibrilsElectron microscope images of amyloid fibrils formed by the 40-residue beta-amyloid peptide are depicted, with either "twisted" or "striated ribbon" morphologies (left).  Corresponding molecular structural models, based on data from solid-state NMR and electron microscopy are shown (right).Electron microscope images of amyloid fibrilsEnlarge
    Custom-built apparatus for solid state NMR at low temperatures with dynamic nuclear polarization (DNP)A custom-built apparatus for solid-state NMR at low temperatures with dynamic nuclear polarization (DNP) is depicted (left).  A carbon-13 NMR spectrum of an isotopically labeled peptide in frozen solution at 25 K, with and without signal enhancement from DNP is shown (right).Custom-built apparatus for solid state NMR at low temperatures with dynamic nuclear polarization (DNP)Enlarge
    Structural model for a pentameric assembly of transmembrane segments of the HIV-1 VpuproteinStructural model for a pentameric assembly of transmembrane segments of the HIV-1 Vpu protein, based on solid-state NMR and photochemical crosslinking data.Structural model for a pentameric assembly of transmembrane segments of the HIV-1 VpuproteinEnlarge