U.S. Department of Health and Human Services
Stephen Marx
 

 Contact Info

 
Tel: 301-496-5051
Email: marxs@mail.nih.gov
 

 Select Experience

 
  • M.D.Johns Hopkins University1968
  • B.A.Yale University1964
 

 Related Links

 

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    Specialties
    • Endocrinology
    • Genetics/Genomics

    Research Summary

    Current Research​

    The Genetics and Endocrinology Section studies the genetic bases of primary hyperparathyroidism and its relations to other neoplastic disorders. We have cloned the gene for multiple endocrine neoplasia type 1 and found that it is implicated in many nonhereditary tumors. This tumor suppressor gene encodes a novel protein, menin. We are studying the actions of menin protein by yeast two-hybrid, microarray, knockout, and other approaches. We have identified an important interaction of menin with junD, a nuclear transcription factor.