U.S. Department of Health and Human Services
Susan Buchanan
 

 Contact Info

 
Tel: 301-594-9222
Email: skbuchan@helix.nih.gov
 

 Select Experience

 
  • Ph.D.Frankfurt University1990
  • M.S.Princeton University1986
  • B.S.Furman University1983
 

 Related Links

 
Specialties
  • Structural Biology

​Publications

A selection of recent and significant publications can be viewed below.

Publications
Noinaj N, Kuszak AJ, Balusek C, Gumbart JC, Buchanan SK. Lateral Opening and Exit Pore Formation Are Required for BamA Function. . [Full Text/Abstract]
Buchanan S, Burt E, Orris P. Beyond black lung: Scientific evidence of health effects from coal use in electricity generation. J Public Health Policy. ; 35:266-77. [Full Text/Abstract]
Noinaj N, Buchanan SK. FhaC takes a bow to FHA in the two-partner do-si-do. . [Full Text/Abstract]
Noinaj N, Buchanan SK. Structural insights into the transport of small molecules across membranes. Curr Opin Struct Biol. ; 27C:8-15. [Full Text/Abstract]
Noinaj N, Buchanan SK, Cornelissen CN. The transferrin-iron import system from pathogenic Neisseria species. Mol Microbiol. 2012 Oct; 86:246-57. [Full Text/Abstract]
Webb CT, Selkrig J, Perry AJ, Noinaj N, Buchanan SK, Lithgow T. Dynamic association of BAM complex modules includes surface exposure of the lipoprotein BamC. J Mol Biol. 2012 Sep 28; 422:545-55. [Full Text/Abstract]
Fairman JW, Dautin N, Wojtowicz D, Liu W, Noinaj N, Barnard TJ, Udho E, Przytycka TM, Cherezov V, Buchanan SK. Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis. Structure. 2012 Jul 3; 20:1233-43. [Full Text/Abstract]
Lukacik P, Barnard TJ, Keller PW, Chaturvedi KS, Seddiki N, Fairman JW, Noinaj N, Kirby TL, Henderson JP, Steven AC, Hinnebusch BJ, Buchanan SK. Structural engineering of a phage lysin that targets gram-negative pathogens. Proc Natl Acad Sci U S A. 2012 Jun 19; 109:9857-62. [Full Text/Abstract]
Noinaj N, Easley NC, Oke M, Mizuno N, Gumbart J, Boura E, Steere AN, Zak O, Aisen P, Tajkhorshid E, Evans RW, Gorringe AR, Mason AB, Steven AC, Buchanan SK. Structural basis for iron piracy by pathogenic Neisseria. Nature. 2012 Feb 12; 483:53-8. [Full Text/Abstract]
Barnard TJ, Gumbart J, Peterson JH, Noinaj N, Easley NC, Dautin N, Kuszak AJ, Tajkhorshid E, Bernstein HD, Buchanan SK. Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter. J Mol Biol. 2012 Jan 6; 415:128-42. [Full Text/Abstract]
Hinnebusch BJ, Jarrett CO, Callison JA, Gardner D, Buchanan SK, Plano GV. Role of the Yersinia pestis Ail protein in preventing a protective polymorphonuclear leukocyte response during bubonic plague. Infect Immun. 2011 Dec; 79:4984-9. [Full Text/Abstract]
Yamashita S, Lukacik P, Barnard TJ, Noinaj N, Felek S, Tsang TM, Krukonis ES, Hinnebusch BJ, Buchanan SK. Structural insights into Ail-mediated adhesion in Yersinia pestis. Structure. 2011 Nov 9; 19:1672-82. [Full Text/Abstract]
Fairman JW, Noinaj N, Buchanan SK. The structural biology of β-barrel membrane proteins: a summary of recent reports. Curr Opin Struct Biol. 2011 Aug; 21:523-31. [Full Text/Abstract]
Tong J, Dolezal P, Selkrig J, Crawford S, Simpson AG, Noinaj N, Buchanan SK, Gabriel K, Lithgow T. Ancestral and derived protein import pathways in the mitochondrion of Reclinomonas americana. Mol Biol Evol. 2011 May; 28:1581-91. [Full Text/Abstract]
Noinaj N, Fairman JW, Buchanan SK. The crystal structure of BamB suggests interactions with BamA and its role within the BAM complex. J Mol Biol. 2011 Mar 25; 407:248-60. [Full Text/Abstract]
Udho E, Jakes KS, Buchanan SK, James KJ, Jiang X, Klebba PE, Finkelstein A. Reconstitution of bacterial outer membrane TonB-dependent transporters in planar lipid bilayer membranes. Proc Natl Acad Sci U S A. 2009 Dec 22; 106:21990-5. [Full Text/Abstract]
Dagley MJ, Dolezal P, Likic VA, Smid O, Purcell AW, Buchanan SK, Tachezy J, Lithgow T. The protein import channel in the outer mitosomal membrane of Giardia intestinalis. Mol Biol Evol. 2009 Sep; 26:1941-7. [Full Text/Abstract]
Gatsos X, Perry AJ, Anwari K, Dolezal P, Wolynec PP, Likić VA, Purcell AW, Buchanan SK, Lithgow T. Protein secretion and outer membrane assembly in Alphaproteobacteria. FEMS Microbiol Rev. 2008 Nov; 32:995-1009. [Full Text/Abstract]
Barnard TJ, Dautin N, Lukacik P, Bernstein HD, Buchanan SK. Autotransporter structure reveals intra-barrel cleavage followed by conformational changes. Nat Struct Mol Biol. 2007 Dec; 14:1214-20. [Full Text/Abstract]
Buchanan SK, Lukacik P, Grizot S, Ghirlando R, Ali MM, Barnard TJ, Jakes KS, Kienker PK, Esser L. Structure of colicin I receptor bound to the R-domain of colicin Ia: implications for protein import. EMBO J. 2007 May 16; 26:2594-604. [Full Text/Abstract]
Noinaj N, Guillier M, Barnard TJ, Buchanan SK. TonB-dependent transporters: regulation, structure, and function. Annu Rev Microbiol. 2010; 64:43-60. [Full Text/Abstract]