| Click Here to download a PDF version of this Agenda.* |
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Sponsored by:
- The National Institute of Diabetes and Digestive and Kidney Dieseases (NIDDK)
- The National Institute of Biomedical Imaging and Bioengineering (NIBIB)
- The National Cancer Institute (NCI)
- The National Institute of Allergy and Infectious Diseases (NIAID)
- National Institutes of Health (NIH)
- Department of Health and Human Services (DHHS)
- Juvenile Diabetes Research Foundation International (JDRFI)
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| Monday, April 24, 2006 |
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| 7:00 a.m. - 8:00 a.m. |
Breakfast, Registration, and Poster Mounting |
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| 8:00 a.m. - 8:05 a.m. |
Welcome
Dr. Maren Laughlin, NIDDK
Dr. Roderic Pettigrew, NIBIB
Dr. Robert Goldstein, JDRFI |
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| 8:05 a.m. - 8:15 a.m. |
Welcome and Overview From the Workshop Chairs
Co-Chairs
Dr. Anna Moore, Massachusetts General Hospital
Dr. Alvin Powers, Vanderbilt University Medical Center
Dr. David Harlan, NIDDK |
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| 8:15 a.m. - 8:35 a.m. |
Islet Biology 101: Diabetes and the Pancreas
Dr. Susan Bonner-Weir, Joslin Diabetes Center |
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| 8:35 a.m. - 8:55 a.m. |
The History and Future of Islet and Beta Cell Imaging
Dr. Willy Malaisse, Brussels Free University |
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| Session I: Imaging Transplantation |
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| 8:55 a.m. - 9:00 a.m. |
Brief Introduction
Dr. David Harlan, NIDDK |
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| 9:00 a.m. - 9:20 a.m. |
Molecular Imaging of Transplantation
Dr. Anna Moore, Massachusetts General Hospital |
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| 9:20 a.m. - 9:40 a.m. |
Break and Posters |
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| 9:40 a.m. - 9:55 a.m. |
Imaging Islet Transplantation
Dr. František Saudek, Institute for Clinical and Experimental Medicine, Prague |
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| 9:55 a.m. - 10:10 a.m. |
Imaging Porcine Allo Islet Transplantation Using Positron Emission Tomography
Dr. Torbjorn Lundgren, Karolinska University Hospital |
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| 10:10 a.m. - 10:25 a.m. |
In Vivo Bioluminescence Imaging of Transplanted Islets and Early Detection of Graft Rejection
Dr. Xiaojuan Chen, Northwestern University |
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| 10:25 a.m. - 10:40 a.m. |
In Vivo MR Imaging of Transplanted Pancreatic Islets
Ellen K. Kohlmeir, Northwestern University |
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| 10:40 a.m. - 11:30 a.m. |
Panel Discussion
Moderator: Dr. David Harlan, NIDDK |
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| 11:30 a.m. - 1:00 p.m. |
Lunch (Posters are available for viewing) |
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| Session II: Imaging Islet Mass |
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| 1:00 p.m. - 1:20 p.m. |
General Considerations for PET and Molecular Imaging
Dr. Ian Sweet, University of Washington |
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| 1:20 p.m. - 1:40 p.m. |
Longitudinal Non-Invasive PET-Based Beta Cell Mass Estimates
in a Spontaneous Diabetes Rat Model
Dr. Paul Harris, Columbia University Medical College |
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| 1:40 p.m. - 2:00 p.m. |
Imaging Islet Mass with Bioluminescence
Dr. Alvin Powers, Vanderbilt University Medical Center |
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| 2:00 p.m. - 2:15 p.m. |
Dihydrotetrabenazine as an Imaging Agent for Endogenous Human
and Non-Human Primate Pancreatic Islets
Dr. Eric H. Liu, NIDDK |
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| 2:15 p.m. - 2:30 p.m. |
Mapping and Quantification of the Entire Distribution of Beta
Cells in the Intact Pancreas
Dr. Manami Hara, The University of Chicago |
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| 2:30 p.m. - 3:15 p.m. |
Panel Discussion
Moderator: Dr. Susan Bonner-Weir, Joslin Diabetes Center,
Harvard Medical School |
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| 3:15 p.m. - 3:45 p.m. |
Break and Posters |
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| Session III: Imaging Metabolism and Physiology |
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| 3:45 p.m. - 4:05 p.m. |
PET in Diagnosis of Focal Hyperinsulinism and Pancreatic
Metabolism
Dr. Pirjo Nuutila, University of Turku, Finland |
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| 4:05 p.m. - 4:20 p.m. |
Imaging of Congenital Hyperinsulinism With 18F-L-Fluoro-DOPA
PET and Correlation With Histopathology
Dr. Abass Alavi, Hospital of the University of Pennsylvania |
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| 4:20 p.m. - 4:40 p.m. |
Cell Imaging of the Islet
Dr. Louis Philipson, The University of Chicago |
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| 4:40 p.m. - 4:55 p.m. |
Imaging Insulin Biology With Ins-C-Fluorescent Proteins in
Live Human and Mouse Islets: Insulin Traffic, Secretion
and Diabetes Through the Microscope
Dr. Peter Drain, University of Pittsburgh School of Medicine |
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| 4:55 p.m. - 5:10 p.m. |
3D Structure Studies of the Insulin-Secreting Pancreatic Beta
Cell by Cellular EM Tomography
Dr. Brad Marsh, University of Queensland, Brisbane |
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| 5:10 p.m. - 5:45 p.m. |
Panel Discussion
Moderator: Dr. Alvin Powers, Vanderbilt University Medical Center |
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(Poster viewing open until 6:30 p.m.) |
 Back to Top |
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| Tuesday, April 25, 2006 |
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| Session IV: Imaging Inflammation |
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| 8:00 a.m. - 8:20 a.m. |
Imaging Inflammation
Dr. Chris Contag,
Stanford University |
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| 8:20 a.m. - 8:35 a.m. |
Non-Invasive Imaging of Pancreatic Inflammation in Type 1
Diabetes
Dr. Jason L. Gaglia, Joslin Diabetes Center, Harvard
Medical School |
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| 8:35 a.m. - 8:50 a.m. |
Real Time Imaging of the Pancreas During Development of
Diabetes
Marianne M. Martinic, La Jolla Institute for Allergy and
Immunology |
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| 8:50 a.m. - 9:05 a.m. |
Magnetic Resonance Imaging of Autoimmune Attack in Type 1
Diabetes Progression
Dr. Zdravka Medarova, Massachusetts General Hospital |
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| 9:05 a.m. - 9:40 a.m. |
Panel Discussion
Moderator: Dr. Anna Moore, Massachusetts General Hospital |
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| 9:40 a.m. - 11:40 a.m. |
Posters |
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| 11:40 a.m. - 1:00 p.m. |
Lunch |
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| Session V:
Emerging Technologies and Opportunities |
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| 1:00 p.m. - 1:20 p.m. |
Emerging Technologies: Optical Imaging
Dr. Warren Zipfel, Cornell University |
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| 1:20 p.m. - 1:40 p.m. |
Emerging Technologies: Functional Imaging
Dr. Douglas Rothman, Yale University |
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| 1:40 p.m. - 2:15 p.m. |
Emerging Technologies: New Probes and Contrast Agents
Dr. Dean Sherry, University of Texas, Dallas
Dr. Paul Grayburn, Baylor University Medical Center
Dr. Jeff Bulte, The Johns Hopkins University School of Medicine |
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| 2:15 p.m. - 2:30 p.m. |
Development and Application of New Fluorescent Probes To
Localize Proteins in Live Cells and at the Ultrastructural
Level
Dr. Ben N.G. Giepmans, University of California, San
Diego |
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| 2:30 p.m. - 2:45 p.m. |
MR Microscopy of Mammalian Islets
Dr. Ioannis Constantinidis, University of Florida,
Gainesville |
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| 2:45 p.m. - 3:15 p.m. |
Panel Discussion
Moderator: Dr. Louis Philipson,
The University of Chicago |
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| 3:15 p.m. - 3:30 p.m. |
Wrap-Up and Adjournment
Dr. David Harlan |
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