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​Diabetes Information

  • Phone: 1–888–860-8747
  • TTY: 1–866–569–1162
  • Email: ndic@info.niddk.nih.gov
  • Hours: 8:30 a.m. to 5 p.m. eastern time, M-F

Diabetes Disease Organizations

There are many organizations who provide support for patients and medical professionals. View the full list of Diabetes Disease Organizations (PDF, 293 KB).

Insert G: Januvia (DPP-4 Inhibitor)

Dipepti​dyl (dy-PEP-tih-dil) Peptidase-4 (PEP-tih-dayss-FOR) DPP-4 Inhibitor (in-HIB-ih-tur)

Brand Name Generic Name
 __ Januvia (juh-NOO-vee-uh)  __ sitagliptin (sih-tuh-GLIP-tin) phosphate (FOSS-fayt)

What does th​is type of pill do?

This type of pill lowers your blood glucose by helping your body make more insulin when it's needed, especially right after meals. It also helps keep your liver from putting stored glucose into your blood.

Who should no​t take Januvia?

Talk with your doctor about whether to take this type of pill if

  • you are pregnant, planning to get pregnant, or breastfeeding
  • you have kidney disease
  • you have type 1 diabetes and if you have a condition called diabetic ketoacidosis

What are t​he possible side effects?

This type of pill doesn't cause low blood glucose by itself. But your risk of having low blood glucose goes up if you also take

  • diabetes pills that cause low blood glucose
  • insulin

Your doctor may ask you to take a lower dose of your other diabetes medicines while you take this type of pill.

Possible side effects are

  • a cold
  • runny nose
  • sore throat
  • headache

If you take Januvia and have kidney problems, your health care provider might order blood tests to see how well your kidneys are working.

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