U.S. Department of Health and Human Services

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NIDDK News Item

Aug 13, 2015

In a recent study, restricting dietary fat led to body fat loss at a rate 68 percent higher than cutting the same number of carbohydrate calories when adults with obesity ate strictly controlled diets.

NIDDK Newsletter

Features updates on NIH and NIDDK activities, events, NIDDK-specific plans, and trans-NIH issues.

NIDDK Research Update

Jul 22, 2015

NIDDK News Item

Jul 20, 2015

Results from a clinical trial sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, suggest that the immune-suppressing drug alefacept helps preserve function of insulin-producing beta cells in people with newly diagnosed Type 1 diabetes.

NIDDK News Item

Jul 20, 2015

The U.S. Department of Agriculture (USDA) and National Institutes of Health have partnered to add the NIH Body Weight Planner to USDA’s SuperTracker online tool as a goal-setting resource to help people achieve and stay at a healthy weight.

NIDDK News Item

Jun 11, 2015

It is well-known that exercise is good for you, but how exactly does physical activity improve the function of different tissues and organs in the body?

NIDDK News Item

May 29, 2015

In the largest study to date of hearing loss among Hispanic/Latino adults in the United States, researchers have found that nearly 1 in 7 has hearing loss, a number similar to the general population prevalence.

NIDDK News Item

May 11, 2015

For the first time in a lab, researchers at the National Institutes of Health found evidence supporting the commonly held belief that people with certain physiologies lose less weight than others when limiting calories.

NIDDK News Item

Apr 16, 2015

Heredity accounts for up to 35 percent of small intestinal carcinoid, a rare digestive cancer, according to findings from a team at the National Institutes of Health.

NIDDK News Item

Apr 8, 2015

An over-the-counter drug indicated to treat allergy symptoms limited hepatitis C virus activity in infected mice, according to a National Institutes of Health study.

NIDDK Grantee News

Apr 1, 2015

Chronic kidney disease (CKD) in childhood is associated with neurocognitive deficits. Affected children show worse performance on tests of intelligence than their unaffected siblings and skew toward the lower end of the normal range.

NIDDK Grantee News

Mar 14, 2015

The bile acid derivative 6-ethylchenodeoxycholic acid (obeticholic acid) is a potent activator of the farnesoid X nuclear receptor that reduces liver fat and fibrosis in animal models of fatty liver disease. We assessed the efficacy of obeticholic acid in adult patients with non-alcoholic steatohepatitis.

NIDDK Grantee News

Mar 12, 2015

Obesity is an increasingly prevalent disease regulated by genetic and environmental factors. Emerging studies indicate that immune cells, including monocytes, granulocytes and lymphocytes, regulate metabolic homeostasis and are dysregulated in obesity.

NIDDK News Item

Mar 12, 2015

More than 20 million Americans aged 20 or older may have chronic kidney disease (CKD) and millions more are at risk of developing the disease.

NIDDK News Item

Mar 10, 2015

New research supported by the National Institutes of Health shows how elements of the brain's stress and reward pathways can interact to suppress binge alcohol drinking.

NIDDK Grantee News

Mar 5, 2015

Hypothalamic pro-opiomelanocortin (POMC) neurons promote satiety. Cannabinoid receptor 1 (CB1R) is critical for the central regulation of food intake. Here we test whether CB1R-controlled feeding in sated mice is paralleled by decreased activity of POMC neurons.

NIDDK Newsletter

Subscribe to digestive diseases news and research, updates on the Bowel Control Awareness Campaign, and new and updated publications.

NIDDK Newsletter

Features urologic diseases research and news, and new and updated publications.

NIDDK Newsletter

Provides information on the latest Network of Minority Health Research Investigators’ workshop, member collaborations, awards, news from the oversight committee and more.

NIDDK Newsletter

Features updates on the NIH nutrition research community and share some of the exciting activities taking place. From training opportunities to novel research findings, the NIH Nutrition Quarterly will highlight significant nutrition happenings at NIH.

NIDDK Newsletter

Features important kidney health information.

NIDDK Newsletter

Provides registered dietitians and nutritionists interested in chronic kidney disease updates on new NKDEP diet-related materials and activities, as well as opportunities to assist NKDEP and its efforts.

NIDDK Grantee News

Feb 26, 2015

Hunger is controlled by specialized neural circuits that translate homeostatic needs into motivated behaviors. These circuits are under chronic control by circulating signals of nutritional state, but their rapid dynamics on the timescale of behavior remain unknown.

NIDDK Grantee News

Feb 24, 2015

Urinary tract infections (UTIs) are among the most common bacterial infections, causing considerable morbidity in females. Infection is highly recurrent despite appropriate antibiotic treatment.

NIDDK Grantee News

Feb 21, 2015

The systemic expression of the bile acid (BA) sensor farnesoid X receptor (FXR) has led to promising new therapies targeting cholesterol metabolism, triglyceride production, hepatic steatosis and biliary cholestasis.

NIDDK News Item

Feb 19, 2015

In an NIH-supported clinical trial comparing three drugs for diabetic macular edma (DME), Eylea (aflibercept) provided greater visual improvement, on average, than did Avastin (bevacizumab) or Lucentis (ranibizumab) when vision was 20/50 or worse at the start of the trial.

NIDDK Research Update

Feb 18, 2015

Discovery Provides Insight into Immunity

NIDDK Grantee News

Feb 1, 2015

Satiety and other core physiological functions are modulated by sensory signals arising from the surface of the gut. Luminal nutrients and bacteria stimulate epithelial biosensors called enteroendocrine cells.

NIDDK Grantee News

Feb 1, 2015

The goal of this study was to determine if Head Start participation is associated with healthy changes in BMI.

NIDDK Grantee News

Jan 15, 2015

Type 2 innate lymphoid cells (ILC2s), an innate source of the type 2 cytokines interleukin (IL)-5 and -13, participate in the maintenance of tissue homeostasis. Although type 2 immunity is critically important for mediating metabolic adaptations to environmental cold, the functions of ILC2s in beige or brown fat development are poorly defined.

NIDDK Grantee News

Jan 15, 2015

Hematopoietic stem and progenitor cells (HSPCs) can reconstitute and sustain the entire blood system. We generated a highly specific transgenic reporter of HSPCs in zebrafish.