U.S. Department of Health and Human Services

Advances in Acute and Chronic Pancreatitis: From Development to Inflammation and Repair

6/25/2012 7:00 AM
6/26/2012 7:00 AM
 
No
For questions concerning program content, contact:
Jose Serrano M.D., Ph.D. 
CAPT Medical Corps, U.S. Public Health Service
Director Liver, Pancreas, and GI Neuroendocrinology Programs
Division of Digestive Diseases and Nutrition 
National Institute of Diabetes and Digestive and Kidney Diseases 
Telephone: (301) 594-8871 
Email:  SerranoJ@extra.niddk.nih.gov 

Sherry Brown, M.S.
Operations Coordinator
Division of Digestive Diseases and Nutrition
National Institute of Diabetes and Digestive and Kidney Diseases
Phone: (301) 435-8150
Email: browns3@mail.nih.gov

Rebekah A. Van Raaphorst, M.P.H. 
Lieutenant, U.S. Public Health Service
Health Research Administrator 
Division of Digestive Diseases and Nutrition
National Institute of Diabetes and Digestive and Kidney Diseases
Phone: (301) 594-0056 
Email: vanraaphr@niddk.nih.gov

For questions concerning logistical information or registration, contact:
Michelle Watson
The Scientific Consulting Group, Inc. 
Phone: (301) 670-4990
Email: mwatson@scgcorp.com 
Bethesda
 
Lister Hill Auditorium

Event Details

Meeting Objective:

  1. To enhance our understanding of pancreatic developmental and stem cell biology; pancreatitis (acute and chronic); genetics of pancreatitis; the link between the inflammatory pancreatic microenvironment and neoplasia; and pancreatic neurobiology
  2. To identify new strategies in diagnosis, imaging, and therapy of pancreatitis
  3. To foster collaborative and innovative interdisciplinary translational research
  4. To coalesce the meeting findings into a publication as a roadmap for future National Institutes of Health (NIH) based initiatives

Planning Committee:

  • Christopher Forsmark
  • Steven Freedman
  • Matthias Hebrok
  • Jane Holt
  • Stephen James
  • Marina Pasca di Magliano
  • Jay Pasricha
  • Anil Rustgi
  • Ashok Saluja
  • Jose Serrano
  • Ben Stanger​​​

Agenda

Day 1 - Monday, June 25, 2012

7:30 a.m. Registration
8:00 a.m. Welco​​me
Stephen James, M.D., and Jane Holt
8:10 a.m. Acute Pancreatitis: The View From the 21st Century
Albert B. Lowenfels, M.D.​
8:30 a.m.

Session 1: Pancreatic Development and Regulation of Organogenesis

Chair: Matthias Hebrok, Ph.D.

 
Cell Plasticity in the Pancreas in Development and Disease
Maike Sander, M.D.
 
Acinar Development and Transcriptional Regulatory Networks
Ray MacDonald, Ph.D.
 
Tips, Trunks, and In-between - Development of Pancreatic Duct and Centroacinar Cells
Steven Leach, M.D.
9:15 a.m. Panel Discussion
9:45 a.m. Break
10:00 a.m.

Session 2: Exocrine Pancreatic Stem/Progenitor Cells

Chair: Ben Stanger, M.D., Ph.D.

 
Pancreatic Stem Cells
Derek van der Kooy, Ph.D.
 
Molecular Mechanisms of Pancreatic Regeneration
Roland Schmid, M.D.
 
Identifying Signals and Lineages That Control Pancreatic Regeneration
Charles Murtaugh, Ph.D.
 
Exploiting Acute Experimental Pancreatitis Models to Identify Novel Genes Involved in Exocrine Physiology and Pancreatic Cancer
Francisco X. Real, M.D., Ph.D.
11: 00 a.m. Panel Discussion
11:30 a.m.

Session 3: Pancreatitis and the Microenvironment

Chair: Marina Pasca di Magliano, Ph.D.

 
Utilizing Proteomics to Understand Acute Pancreatitis
John Williams, M.D., Ph.D.
 
Environmental Factors and Protein Processing in the Endoplasmic Reticulum of the Acinar Cell
Stephen Pandol, M.D.
 
Signaling Pathways, Pancreatitis, and the Microenvironment
Matthias Hebrok, Ph.D.
 
Mouse Models of Pancreatitis
Craig Logdson, Ph.D.
12:30 p.m. Panel Discussion
1:00 p.m. Lunch
2:00 p.m.

Session 4: Genetics of Pancreatitis

Chair: Steven Freedman, M.D., Ph.D.

 
Conditional Knockout Mouse Models to Identify Genotype-phenotype Interactions
Mitchell Drumm, Ph.D.
 
Genetic Approaches Common to All Pancreatic Diseases
Peter Durie, M.D.
 
Novel Strategies to Identify Candidate Genes Using Exomic Sequencing Using Renal Disease as an Example
Martin Pollak, M.D.
 
Chymotrypsin C in Hereditary and Sporadic Chronic Pancreatitis
Miklos Sahin-Toth, M.D., Ph.D.
3:00 p.m. Panel Discussion
3:30 p.m. Break
3:45 p.m.

Session 5: Acute Pancreatitis

Chair: Ashok Saluja, Ph.D.

 
Role of Stellate Cells in Alcoholic Pancreatitis
Minoti Apte, Ph.D., M.D.
 
Treatment and Prevention Strategies in Acute Pancreatitis
Bechien Wu, M.D., M.P.H.
 
The Role of Proteases in Pancreatitis
Markus Lerch, M.D.
4:45 p.m. Panel Discussion
5:15 p.m. Adjournment

Day 2 -Tuesday, June ​26, 2012

7:30 a.m.

Registration

8:00 a.m. Introduction
Anil Rustgi, M.D.
8:15 a.m.

Session 6: Chronic Pancreatitis

Chair: Chris Forsmark, M.D.

 
Current and Future Strategies for Early Diagnosis
Darwin Conwell, M.D., M.S.
 
Chronic Pancreatitis: Relevance of Animal Models to Human Disease
Fred Gorelick, M.D.
 
Environmental and Non-genetic Risk Factors for Chronic Pancreatitis
Dhiraj Yadav, M.D., M.P.H.
 
Framing the Critical Problems of Chronic Pancreatitis
David Whitcomb, M.D.
9:15 a.m. Panel Discussion
9:45 a.m. Break
10:00 a.m.

Session 7: Inflammation and Pancreatic Neoplasia

Chair: P. Jay Pashrica, M.D.

 
Clinical Needs
Michael Levy, M.D.
 
Molecular Mechanisms of Pain in Chronic Pancreatitis
P. Jay Pashrica, M.D.
 
Neurogenic Pancreatitis
Rodger Liddle, M.D.
 
The Neural Microenvironment in the Pancreas
Gustavo Ayala, M.D.
11:00 a.m. Panel Discussion
11:35 a.m. Closing Remarks
Anil Rustgi, M.D.
12:00 p.m. Adjournment

Directions/Travel

Meeting Location:

Lister Hill Auditorium
Building 38 A
National Institutes of Health
Bethesda, MD

NIH Visitor Information:

The Lister Hill Auditorium is located on the NIH Campus in building 38A. For a map, general information, and directions to and around the NIH Campus, visit: http://parking.nih.gov/visitor_access_map.htm .

NIH Security:

The NIH, like all federal government facilities, has instituted security measures to ensure the safety of NIH employees, patients, and visitors. The national threat advisory level, determined by the Department of Homeland Security ( http://www.whitehouse.gov/homeland ), currently is yellow (elevated).

Perimeter Security:

All visitor vehicles, including taxicabs, hotel and airport shuttles, delivery trucks, and vans will be inspected before being allowed on campus. Visitors will be asked to show one (1) form of identification (a government-issued photo ID: driver's license, passport, green card, etc.) and to state the purpose of their visit. Be sure to allow at least 15-20 minutes for this vehicle inspection procedure.

Building Security:

Due to the checking of IDs at the perimeter, employees and visitors will not be required to show their ID again to gain access to the majority of buildings on the NIH Campus during the normal business day.
 
Employees and visitors should continue to wear their identification prominently at all times while on campus.
 
Guards will remain at certain buildings to address specific program requirements, such as sensitive research and safety concerns. At building entrances where guards are posted:
  • Employees must show a DHHS-issued photo ID (for example, your NIH-issued ID badge).
  • Visitors may be required to log-in, wear a visitor's pass, and be escorted by an employee through the building.
  • Visitors may be required to pass through a metal detector and have bags, backpacks, or purses inspected or x-rayed as they enter buildings.
  • Security staff will confiscate any suspicious or potentially dangerous materials. U.S. code prohibits bringing any dangerous weapons onto federal property, including anything with a blade longer than 2" inches. Meeting participants may want to leave extra bags or personal materials at their hotel to minimize the time needed for inspection.

Weekday Pedestrian Campus Access:

All visitors must enter through the NIH Gateway Center at Metro or the West Gateway Center (see the Visitor Map at http://parking.nih.gov/visitor_access_map.htm ).
  • Gateway Center
    Wisconsin Avenue at Gateway Drive (near the Metro)
    Open 24 hours, 7 days per week
  • West Gateway Center
    Near Old Georgetown Road and South Drive
    Open 6 a.m. - 12 p.m., Monday-Friday

DRIVING DIRECTIONS TO NIH:

From Points North and East:

Take I-95 South to I-495 West (Capital Beltway) toward Silver Spring. Follow I-495 West for 9 miles to Exit 34 (Bethesda/Wisconsin Avenue). Follow signs for Route 355 South and stay in the right lane. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 38A.

From Points North and West:Take I-270 South to I-495 East (Capital Beltway) toward Washington, DC. Stay in one of the three left lanes. Follow signs for Route 355 South, a left-lane exit, onto Wisconsin Avenue. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 38A.
Take I-270 South to I-495 East (Capital Beltway) toward Washington, DC. Stay in one of the three left lanes. Follow signs for Route 355 South, a left-lane exit, onto Wisconsin Avenue. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 38A.
Take I-270 South to I-495 East (Capital Beltway) toward Washington, DC. Stay in one of the three left lanes. Follow signs for Route 355 South, a left-lane exit, onto Wisconsin Avenue. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 38A.

From Points South:

Take I-95 North to I-495 (Capital Beltway) toward Tyson's Corner/Rockville. Follow I-495 for 20 miles. Take Exit 34 (Bethesda/Wisconsin Avenue). Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 38A.

From Baltimore/Washington International Thurgood Marshall Airport (BWI):
Take the Route 195 connector to I-95 South. Take I-95 South to I-495 West (Capital Beltway) toward Silver Spring. Follow I-495 West for 9 miles to Exit 34 (Bethesda/Wisconsin Avenue). Follow signs for Route 355 South and stay in the right lane. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 38A.

From Washington Dulles International Airport (IAD):
Take the Dulles Access Road for approximately 13 miles to Exit 18. Move to the right on the Dulles Toll Road (Route 267) and take Exit 18. Stay left on the ramp for Bethesda/Baltimore, and proceed toward Bethesda (I-495). Continue approximately 9 miles on I-495. Stay on I-495 at the I-495/I-270 split (bear right). Take Exit 34 (Wisconsin Avenue South/Route 355) toward Bethesda. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 38A.

From Ronald Reagan Washington National Airport (DCA):
Take the George Washington Parkway North for 12 miles to I-495 toward Maryland (Capital Beltway). Take Exit 34 (Bethesda/Wisconsin Avenue). Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 38A.

PARKING: 

Parking on the NIH campus is limited and is $12 per day in the visitor lots.

Hotel Lodging:

Hyatt Regency Bethesda Hotel
One Bethesda Metro Center
7400 Wisconsin Avenue
Bethesda, MD 20814
Telephone: (888) 421-1442 for toll free OR (402) 592-6464 (non toll free)

Hotel Accommodations:

A block of sleeping rooms has been reserved at the Hyatt Regency Bethesda, Bethesda, MD, for arrival on Sunday, June 24, 2012, and departing on Tuesday, June 26, 2012. The room rate is $224 plus tax per night. You will be responsible for the room cost and your incidental charges upon checkout.

Please contact the Hyatt Regency Bethesda the extended cut-off date Friday, June 1, 2012, at (888) 421-1442 for toll free OR (402) 592-6464 (non toll free) , and reference the NIDDK's Advances in Acute and Chronic Pancreatitis Meeting when making your sleeping room reservations. For online registrations, please use the meeting code PANC at the following link: https://resweb.passkey.com/go/PANC. Please be certain that the hotel provides you with a confirmation number and retain this number for future reference. After June 1, 2012, the hotel will accept reservations on a space-available basis at the prevailing hotel rate.

When making a reservation, please provide your room and bedding preferences. The hotel will assign specific room types at check-in, based on availability. Please be advised that requests are not guaranteed. Check-in time is at 3:00 p.m., and check-out time is 12:00 noon. If for any reason you need to cancel your hotel reservation, please do so 48 hours in advance of your check-in date.
 
Additional Information:
The Scientific Consulting Group, Inc. (SCG) is providing the logistical support for this meeting. The above information should help you with your planning. If you have any questions, please contact Michelle Watson of SCG by telephone at 301-670-4990 or by email at mwatson@scgcorp.com .

DIRECTIONS:

From Points North:

From I-95:
Take I-95 South to I-495 (Capital Beltway) West toward Silver Spring. Take Exit 34 (Wisconsin Avenue/Route 355). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.

From I-270:
Take I-270 South to I-495 (Capital Beltway) East toward Washington, DC. Stay in one of the three left lanes. Follow signs for 355 South, a left-lane exit, onto Wisconsin Avenue. Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.

From Points South

Take I-95 North to I-495 (Capital Beltway) toward Tysons Corner/Rockville. Follow I-495 for 20 miles. At the I-495/I-270 split, stay to the right on I-495. Take Exit 34 (Wisconsin Avenue/Route 355). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.

From Baltimore/Washington International Thurgood Marshall Airport (BWI)

Take Route 195 West to Exit 4 (I-95 South). From I-95 take I-495 (Capital Beltway) West toward Silver Spring. Take Exit 34 (Wisconsin Avenue/Route 355). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.

From Washington Dulles International Airport

Take the Dulles Access Road for approximately 13 miles to Exit 18. Move to the right on the Dulles Toll Road (Route 267); get off at Exit 18. Stay to the left on the ramp for Bethesda/Baltimore and proceed toward Bethesda on I-495 (Capital Beltway) for approximately 9 miles. At the I-495/I-270 split, stay to the right on I-495. Take Exit 34 (Wisconsin Avenue/Route 355 South). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.

From Ronald Reagan National Airport

Take the George Washington Parkway North to I-495 (Capital Beltway) and follow the signs to Maryland. At the I-495/I-270 split, stay to the right on I-495. Take Exit 34 (Wisconsin Avenue/Route 355). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.

METRO INFORMATION:

The Metro System is clean, reliable, and safe. It operates from 5:30 a.m. to 12:00 midnight Monday through Thursday; 5:00 a.m. to 2:00 a.m. on Fridays; 8:00 a.m. to 2:00 a.m. on Saturdays; and 8:00 a.m. to 12:00 midnight on Sundays. Each passenger must buy a farecard to travel in the system. Guides for purchasing farecards are posted on the vending machines in each station. Each Metro car features a complete color-coded map. Station attendants on duty at each station can provide additional information on request.
 
From Union Station or downtown Washington (main Metro Lines into the city converge at Metro Center Station and Gallery Place Station), take the Metro Red Line toward Shady Grove or Grosvenor. Exit at the Bethesda Metro Station. The Hyatt is directly above the Bethesda Metro Station.

SHUTTLES:

SuperShuttle offers service to most hotels from Ronald Reagan National Airport, Washington Dulles International Airport, and Baltimore/Washington International Thurgood Marshall Airport. The shuttle leaves on an as-needed basis between the hours of 5:30 a.m. and 11:00 p.m. During other times, arrange for a shuttle by calling 800-258-3826 from the airport.

TAXIS:

The taxi fare is approximately $45-$55 from Ronald Reagan Washington National Airport, approximately $55-$65 from Washington Dulles International Airport, and approximately $65-$75 from Baltimore/Washington International Thurgood Marshall Airport. Fares may differ during peak travel hours.

MARC TRAINS:

From BWI Airport, take the MARC train on the Penn Line to Union Station. Take the Metro Red Line toward Grosvenor or Shady Grove and exit at the Bethesda Metro Station. The hotel is directly above the Bethesda Metro Station.

PARKING INFORMATION:  

Self-parking at the hotel is $15 per day/overnight. Valet parking is $20 per day/overnight. 

Minutes

​​Minutes are currently unavailable

Attendees

​​Attendees are currently unavailable

Abstracts

​​Abstracts are currently unavailable

Location

Line
  • Building 38A, NIH Campus
  • MD 20892
Webinar

Contacts

Line
For questions concerning program content, contact:
Jose Serrano M.D., Ph.D. 
CAPT Medical Corps, U.S. Public Health Service
Director Liver, Pancreas, and GI Neuroendocrinology Programs
Division of Digestive Diseases and Nutrition 
National Institute of Diabetes and Digestive and Kidney Diseases 
Telephone: (301) 594-8871 
Email:  SerranoJ@extra.niddk.nih.gov 

Sherry Brown, M.S.
Operations Coordinator
Division of Digestive Diseases and Nutrition
National Institute of Diabetes and Digestive and Kidney Diseases
Phone: (301) 435-8150
Email: browns3@mail.nih.gov

Rebekah A. Van Raaphorst, M.P.H. 
Lieutenant, U.S. Public Health Service
Health Research Administrator 
Division of Digestive Diseases and Nutrition
National Institute of Diabetes and Digestive and Kidney Diseases
Phone: (301) 594-0056 
Email: vanraaphr@niddk.nih.gov

For questions concerning logistical information or registration, contact:
Michelle Watson
The Scientific Consulting Group, Inc. 
Phone: (301) 670-4990
Email: mwatson@scgcorp.com