U.S. Department of Health and Human Services

Targeting Fibrosis in Kidney, Bone Marrow, and Urological Diseases

1/7/2014 7:30 AM
1/7/2014 5:00 PM
No
No
(301) 657-1234 or (800) 233-1234
(301) 657-6453

For questions concerning program content, contact:
Michael F. Flessner, M.D., Ph.D.
Director of Inflammatory Renal Diseases
Division of Kidney, Urologic, and Hematologic Diseases
National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health
Two Democracy Plaza, Room 641
6707 Democracy Boulevard, MSC 5458
Bethesda, MD  20892-5458
Telephone: (301) 451-4901
Email: flessnermf@niddk.nih.gov

For questions concerning meeting logistics, contact:
John Hare, M.S., CMP, CGMP
The Scientific Consulting Group, Inc.
656 Quince Orchard Road, Suite 210
Gaithersburg, MD  20878
Telephone: (301) 670-4990
Fax: (301) 670-3815
Email: jhare@scgcorp.com

Bethesda
 
Hyatt Regency Bethesda Hotel

Event Details

Meeting Focus

Discuss Means of Detecting and Measuring Pathologic Fibrosis in Humans

Questions to be answered:

  1. Can we differentiate between pathologic fibrosis and that of normal aging?
  2. Does fibrosis correlate with organ dysfunction?
  3. Does imaging of fibrosis correlate with organ dysfunction, recovery, and regression?
  4. What novel biomarkers or technologies should be pursued to detect and measure pathologic fibrosis?

Steering Committee:

NIDDK Members: Tamara Bavendam, Terry Bishop, Ed Doo, Deborah Hoshizaki, Chris Ketchum,
Ziya Kirkali, Maren Laughlin, Tracy Rankin, and Krystyna Rys-Sikora
 
NIBIB Member: Christina Liu
​​​​​​​

Agenda

January 7, 2014

7:30 a.m. Registration
8:30 a.m. Opening Remarks and Objectives
Dr. Griffin Rodgers
8:45 a.m. State-of-the-Art Lectures (20 min. each followed by 10 min. discussion)

Moderator: Dr. Deborah Hoshizaki
Mechanisms of Fibrosis – Dr. Thomas Wynn
JAK2 Story in Myelofibrosis – Dr. Kenneth Kaushansky
Advances in Liver Fibrosis Research – Dr. Scott Friedman
10:15 a.m. Break
10:45 a.m. Detection (Imaging) of Pathologic Fibrosis (20 min. + 10 min. for questions)

Moderator: Dr. Maren Laughlin
Molecular Imaging – Dr. Bryan Fuchs
New Tools for Measuring and Understanding Pathologic Fibrosis – Dr. Ben Humphreys
Fibrosis and Prostate Disease – Dr. William Ricke
12:15 p.m.
Lunch (on your own)
A box lunch may be ordered the morning of the workshop with this form.​
1:15 p.m. Pathologic Fibrosis and Organ Dysfunction (20 min. + 10 min. for questions)

Moderator: Dr. Terry Bishop
Urinary Obstruction and Fibrosis – Dr. Jill Macoska
Biology of Fibrosis and Mechanisms for Reversal Therapy – Dr. Raghu Kalluri
Hematologic Fibrosis: Monitoring Dysfunction and Recovery – Dr. Joachim Deeg
2:45 p.m. Break
3:15 p.m. FDA Procedures for Qualification (20 min. each + 10 min. for questions)

Moderator: Dr. Michael Flessner
Perspectives on Biomarker Test Validation From OIR/CDRH at FDA – Dr. Kellie Kelm
Biomarker Qualification at CDER, FDA – Dr. Shashi Amur
Device Qualification – Dr. Brian Garra
4:45 p.m. Summary – Dr. Robert Star and Dr. Michael Flessner
5:00 p.m. Adjournment

Directions/Travel

Air Travel

Travel arrangements are your own responsibility, but you should know that three airports (listed below) serve the Washington, DC, metropolitan area. Please make your own air or rail reservations.
 
If you decide to extend your stay to take advantage of lower fares, DC-area attractions are only a short distance away from the host hotel.
 
Hotel and travel information are listed below.

Accommodations

A block of sleeping rooms has been reserved at the following hotel:
 
Hyatt Regency Bethesda Hotel
One Bethesda Metro Center
7400 Wisconsin Avenue
Bethesda, MD  20814
Telephone: (301) 657-1234 or (800) 233-1234
Fax: (301) 657-6453
Website: http://www.hyattregencybethesda.com
(More hotel information can be obtained from this website.)
 
A limited number of sleeping rooms have been reserved at the Hyatt Regency Bethesda Hotel. The rate is $139 per night for single occupancy, plus tax (13%). To reserve a hotel room at the group rate, call reservations at (888) 421-1442 and identify yourself as a member of the Targeting Fibrosis Meeting, or book online at: https://aws.passkey.com/g/20931843. THE ROOM BLOCK WILL BE IN EFFECT AT THE GOVERNMENT RATE ONLY UNTIL FRIDAY, DECEMBER 20, 2013, OR UNTIL FULL, WHICHEVER COMES FIRST. ANY ROOM RESERVATIONS RECEIVED AFTER THIS DATE WILL BE ACCEPTED ON A SPACE- AND RATE-AVAILABILITY BASIS. Reservations should be made for arrival on January 6, 2014, with departure on January 7, 2014. If you require alternate dates, please send an email to John Hare of The Scientific Consulting Group, Inc. (SCG) at: jhare@scgcorp.com.
 
Please be certain that the hotel provides you with a confirmation number for your reservation. After December 20, 2013, the official room block will be released, and the hotel may charge significantly higher rates and may be sold out. When making a reservation, please provide your room and bedding preferences. The hotel will assign specific room types at check-in, based on availability. Please be advised that requests are not guaranteed. Check-in time is 3:00 p.m., and check-out time is 12:00 p.m. If you need to cancel your reservation, please do so by 3:00 p.m. on the day prior to arrival, or you will be charged a no-show fee for 1 night on your credit card.

Taxi Service to Hotel

From Baltimore/Washington International Thurgood Marshall Airport (BWI):
Approximate hotel distance and direction: 35 miles southwest
Estimated Taxi Fare: $65–$75
 
From Washington Dulles International Airport (IAD):
Approximate hotel distance and direction: 25 miles northeast
Estimated Taxi Fare: $55–$65
 
From Ronald Reagan Washington National Airport (DCA):
Approximate hotel distance and direction: 21 miles northeast
Estimated Taxi Fare: $45–$55
 
Barwood Taxi frequents the NIH campus and can be reached at (301) 984-1900 or (800) 831-2323. All three airports have taxis available and waiting.

Metro to the Hotel

The Metro system is clean and reliable. It operates from 5:00 a.m. to 12:00 midnight on Mondays through Thursdays; 5:00 a.m. to 3:00 a.m. on Fridays; 7:00 a.m. to 3:00 a.m. on Saturdays; and 7:00 a.m. to 12:00 midnight on Sundays. Each passenger must purchase a farecard to travel in the system. Instructions for purchasing farecards are posted on the vending machines in each station. Each Metro car features a complete, color-coded map of the system. Station attendants on duty at each station can provide additional information on request. From Ronald Reagan Washington National Airport, a cost-effective way to travel to the meeting is by using the Metrorail system. A map of the system is available at: http://www.wmata.com/rail/maps/map.cfm.
 
From the Ronald Reagan Washington National Airport station, take the Yellow Line toward Mt. Vernon Square or Fort Totten. At the Gallery Place/Chinatown stop, transfer to the Red Line toward Shady Grove or Grosvenor-Strathmore. For arrival at the hotel, exit at the Bethesda Station.

SuperShuttle

SuperShuttle offers service to most hotels from Ronald Reagan Washington National Airport, Washington Dulles International Airport, and Baltimore/Washington International Thurgood Marshall Airport. The shuttle leaves on an as-needed basis between the hours of 5:30 a.m. and 11:00 p.m. During other times, arrangements for a shuttle can be made by calling (800) 258-3826 from the airport, or visit their website at: http://supershuttle.com.

Driving Directions to the Hotel

From Points North and East:
Take I-95 South to I-495 West (Capital Beltway) toward Silver Spring. Follow I-495 West for 9 miles to Exit 34 (Bethesda/Wisconsin Avenue). Follow signs for Route 355 South, and stay in the right lane. Travel approximately 1.5 miles and the hotel will be on your right.
 
From Points North and West:
Take I-270 South to I-495 East (Capital Beltway) toward Washington, DC. Stay in one of the three left lanes. Follow signs for Route 355 South, a left-lane exit, onto Wisconsin Avenue. Travel approximately 1.5 miles and the hotel will be on your right.
 
From Points South:
Take I-95 North to I-495 (Capital Beltway) toward Tyson's Corner/Rockville. Follow I-495 for 20 miles. Take Exit 34 (Bethesda/Wisconsin Avenue). Travel approximately 1.5 miles and the hotel will be on your right.
 
From Baltimore/Washington International Thurgood Marshall Airport (BWI):
Take the Route 195 connector to I-95 South. Take I-95 South to I-495 West (Capital Beltway) toward Silver Spring. Follow I-495 West for 9 miles to Exit 34 (Bethesda/Wisconsin Avenue). Follow signs for Route 355 South, and stay in the right lane. Travel approximately 1.5 miles and the hotel will be on your right.
 
From Washington Dulles International Airport (IAD):
Take the Dulles Access Road for approximately 13 miles to Exit 18. Move to the right on the Dulles Toll Road (Route 267) and take Exit 18. Stay left on the ramp for Bethesda/Baltimore, and proceed toward Bethesda (I-495). Continue approximately 9 miles on I-495. Stay on I-495 at the I-495/I-270 split (bear right). Take Exit 34 (Wisconsin Avenue South/Route 355) toward Bethesda. Travel approximately 1.5 miles and the hotel will be on your right.
 
From Ronald Reagan Washington National Airport (DCA):
Take the George Washington Parkway North for 12 miles to I-495 (Capital Beltway) toward Maryland. Take Exit 34 (Bethesda/Wisconsin Avenue). Travel approximately 1.5 miles and the hotel will be on your right.

Parking

There is a parking garage under the hotel. Self-parking for overnight guests is $20. The self-park day rate is $12.

Minutes

​Minutes are available here in PDF format.

Attendees

​​Attendees are currently unavailable.

Abstracts

​​Abstracts are currently unavailable.

Location

Line
  • One Bethesda Metro Center
  • 7400 Wisconsin Avenue
  • MD 20814
Webinar

Contacts

Line

For questions concerning program content, contact:
Michael F. Flessner, M.D., Ph.D.
Director of Inflammatory Renal Diseases
Division of Kidney, Urologic, and Hematologic Diseases
National Institute of Diabetes and Digestive and Kidney Diseases
National Institutes of Health
Two Democracy Plaza, Room 641
6707 Democracy Boulevard, MSC 5458
Bethesda, MD  20892-5458
Telephone: (301) 451-4901
Email: flessnermf@niddk.nih.gov

For questions concerning meeting logistics, contact:
John Hare, M.S., CMP, CGMP
The Scientific Consulting Group, Inc.
656 Quince Orchard Road, Suite 210
Gaithersburg, MD  20878
Telephone: (301) 670-4990
Fax: (301) 670-3815
Email: jhare@scgcorp.com