U.S. Department of Health and Human Services

Urologic Complications of Diabetes: Developing a Basic Research Strategy

2/14/2013 7:00 AM
2/15/2013 7:00 AM
Yes
No
For questions concerning general program content, contact:
Tracy L. Rankin, Ph.D.
Program Director, Career Development and Training
Division of Kidney, Urologic and Hematologic Diseases
National Institute of Diabetes and Digestive and Kidney Diseases
Telephone: (301) 594-4748
Email: rankint@niddk.nih.gov

For questions concerning logistical information or registration, contact:
Michelle Watson
The Scientific Consulting Group, Inc.
Telephone: (301) 670-4990
Email: mwatson@scgcorp.com
Bethesda
 

Event Details

Meeting Objective

The intent of this conference is to provide a state-of-the-science overview on the effects of diabetes on cellular systems relevant to urologic complications: smooth muscle, autonomic nervous system, endothelium, and vasculature, and to discuss how this knowledge can be leveraged for urologic research.Speakers and participants will discuss how best to integrate the basic science expertise and knowledge with clinical urology expertise to identify basic research priorities.

Tracy Rankin, Ph.D., National Institute of Diabetes and Digestive and Kidney Diseases
Kristin Abraham, Ph.D., National Institute of Diabetes and Digestive and Kidney Diseases
Simon J. Gibbons, Ph.D., Mayo Clinic
Ziya Kirkali, M.D., National Institute of Diabetes and Digestive and Kidney Diseases
Robert S. Moreland, Ph.D., Drexel University
Aruna Sarma, Ph.D., University of Michigan

Agenda

Thursday, February 14, 2013

8:30 a.m. Introduction to the Workshop and Statement of Overall Goals
Tracy Rankin, Ph.D., NIDDK
Robert Star, M.D., NIDDK
8:45 a.m.

 

Session I: Epidemiology of Urologic Complications:

What are the Known Unknowns?

Hunter Wessells, M.D., University of Washington
Leslee Subak, M.D., University of California, San Francisco
Jennifer St. Sauver, Ph.D., Mayo Clinic

 

10:30 a.m. Breakout Session I: Presentation of Outstanding Questions/Goals/Issues
11: 00 a.m.

Session II: Smooth and Cardiac Muscle Physiology

Coronary Smooth Muscle Ca 2+ Dysregulation in Metabolic Syndrome Swine: Principles for Urologic Smooth Muscle
Michael Sturek, Ph.D., Indiana University School of Medicine
 
Neuropilin 2: A New Player in Bladder Pathophysiology?
Rosalyn Adam, Ph.D., Children's Hospital Boston
 
A Trek to Understanding Diabetes' (and Obesity's) Effects on the Heart Muscle
Linda Peterson, M.D., Washington University School of Medicine at St. Louis
12:45 p.m. Lunch Break
2:00 p.m. Special Presentation: Basic Science Foundation of Translational Research in Regenerative Medicine Anthony Atala, M.D., Wake Forest University
2:45 p.m.

Session III: Inflammation and Fibrosis

Inflammation and Fibrosis Promote Lower Urinary Tract Dysfunction
Jill Macoska, Ph.D., University of Michigan
 
PAF Signaling in Kidney Inflammation, Dysfunction, and Fibrosis
Thomas McIntyre, Ph.D., Cleveland Clinic
 
The Role of Inflammation in Pulmonary Fibrosis
Erica Herzog, M.D., Ph.D., Yale University
4:15 p.m.

Session IV: Neural Responses and Central Mechanisms

Cellular and Molecular Basis for Diabetic Gastroparesis
Gianrico Farrugia, M.D., Mayo Clinic
 
Nitrinergic Pathways and Diabetes
Pankaj "Jay" Pasricha, M.D., The Johns Hopkins University
 
Mitochondrial Function in Diabetic Neuropathy
James Russell, M.D., M.S., University of Maryland
6:00 p.m. Day 1 Wrap-up/Discussion
6:30 p.m. Dinner on your own

Friday, February 15, 2013

8:30 a.m.

Session V: Bioenergetics/Oxidative Stress

Inflammation and Protein Carbonylation
David Bernlohr, Ph.D., University of Minnesota
 
Role of mTORC1 Activation in the Development of Diabetic Nephropathy
Kenneth Inoki, M.D., Ph.D., University of Michigan
 
Robert Balaban, Ph.D., National Heart, Lung, and Blood Institute, NIH
10:15 a.m.

Session VI: Resources and Tools

The GUDMAP Database: A Resource for Urologic Research
Chad Vezina, Ph.D.; and Bruce Aronow, University of Wisconsin and Cincinnati Children's
 
Mining Human Biosamples for Mechanism and Targets in Diabetic End Organ Complications
Matthias Kretzler, M.D., University of Michigan
 
Applications of Metabolomics in Urology
Susan Sumner, Ph.D., Research Triangle Institute
12:00 p.m.

Breakout Session II: Coming Back to the Original Questions in the Context of the Science Presented; Prioritization by Topic Area for Research Moving Forward-What is Most Important to Investigate First?

1:00 p.m. Meeting Summation and Adjournment

Directions/Travel

Hotel Lodging:

Hyatt Regency Bethesda Hotel
One Bethesda Metro Center
7400 Wisconsin Avenue
Bethesda, MD 20814
Telephone: (301) 657-1234 or (888) 421-1442

Hotel Accommodations:

A block of sleeping rooms has been reserved at the Hyatt Regency Bethesda, Bethesda, MD, for arrival on Wednesday, February 13, 2013, and departing on Friday, February 15, 2013. The room rate is $183 plus tax per night. You will be responsible for the room cost and your incidental charges upon checkout. 

Please contact the Hyatt Regency Bethesda by Wednesday, January 23, 2013, at (301) 657-1234 or 1 (888) 421-1442, and reference the NIDDK's Urologic Complications Meeting when making your sleeping room reservations. For online registrations, please use the following link: https://resweb.passkey.com/Resweb.do?mode=welcome_ei_new&eventID=10350833&utm_source=14877&utm_medium=email&utm_campaign=21200820 . Please be certain that the hotel provides you with a confirmation number. After January 23, 2013, the hotel will accept reservations on a space-available basis at the prevailing hotel rate.
 
When making a reservation, please provide your room and bedding preferences. The hotel will assign specific room types at check-in, based on availability. Please be advised that requests are not guaranteed. Check-in time is at 3:00 p.m., and check-out time is 12:00 noon. If for any reason you need to cancel your hotel reservation, please do so 48 hours in advance of your check-in date.

Additional Information

The Scientific Consulting Group, Inc. (SCG) is providing the logistical support for this meeting. The above information should help you with your planning. If you have any questions, please contact Michelle Watson of SCG by telephone at 301-670-4990 or by email at mwatson@scgcorp.com .

Directions

From Points North
From I-95: Take I-95 South to I-495 (Capital Beltway) West toward Silver Spring. Take Exit 34 (Wisconsin Avenue/Route 355). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.
 
From I-270: Take I-270 South to I-495 (Capital Beltway) East toward Washington, DC. Stay in one of the three left lanes. Follow signs for 355 South, a left-lane exit, onto Wisconsin Avenue. Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.
 
From Points South
Take I-95 North to I-495 (Capital Beltway) toward Tysons Corner/Rockville. Follow I-495 for 20 miles. At the I-495/I-270 split, stay to the right on I-495. Take Exit 34 (Wisconsin Avenue/Route 355). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.
 
From Baltimore/Washington International Thurgood Marshall Airport (BWI)
Take Route 195 West to Exit 4 (I-95 South). From I-95 take I-495 (Capital Beltway) West toward Silver Spring. Take Exit 34 (Wisconsin Avenue/Route 355). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.
 
From Washington Dulles International Airport
Take the Dulles Access Road for approximately 13 miles to Exit 18. Move to the right on the Dulles Toll Road (Route 267); get off at Exit 18. Stay to the left on the ramp for Bethesda/Baltimore and proceed toward Bethesda on I-495 (Capital Beltway) for approximately 9 miles. At the I-495/I-270 split, stay to the right on I-495. Take Exit 34 (Wisconsin Avenue/Route 355 South). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.
 
From Ronald Reagan National Airport
Take the George Washington Parkway North to I-495 (Capital Beltway) and follow the signs to Maryland. At the I-495/I-270 split, stay to the right on I-495. Take Exit 34 (Wisconsin Avenue/Route 355). Follow Route 355 South for approximately 3 miles and the Hyatt Regency Bethesda will be on the right, on the corner of Wisconsin Avenue and Old Georgetown Road.

METRO INFORMATION

The Metro System is clean, reliable, and safe. It operates from 5:30 a.m. to 12:00 midnight Monday through Thursday; 5:00 a.m. to 2:00 a.m. on Fridays; 8:00 a.m. to 2:00 a.m. on Saturdays; and 8:00 a.m. to 12:00 midnight on Sundays. Each passenger must buy a farecard to travel in the system. Guides for purchasing farecards are posted on the vending machines in each station. Each Metro car features a complete color-coded map. Station attendants on duty at each station can provide additional information on request.
 
From Union Station or downtown Washington (main Metro Lines into the city converge at Metro Center Station and Gallery Place Station), take the Metro Red Line toward Shady Grove or Grosvenor. Exit at the Bethesda Metro Station. The Hyatt is directly above the Bethesda Metro Station.

SHUTTLES

SuperShuttle offers service to most hotels from Ronald Reagan National Airport, Washington Dulles International Airport, and Baltimore/Washington International Thurgood Marshall Airport. The shuttle leaves on an as-needed basis between the hours of 5:30 a.m. and 11:00 p.m. During other times, arrange for a shuttle by calling 800-258-3826 from the airport.

TAXIS

The taxi fare is approximately $45-$55 from Ronald Reagan Washington National Airport, approximately $55-$65 from Washington Dulles International Airport, and approximately $65-$75 from Baltimore/Washington International Thurgood Marshall Airport. Fares may differ during peak travel hours.

MARC TRAINS

From BWI Airport, take the MARC train on the Penn Line to Union Station. Take the Metro Red Line toward Grosvenor or Shady Grove and exit at the Bethesda Metro Station. The hotel is directly above the Bethesda Metro Station.

PARKING INFORMATION

Self-parking at the hotel is $15 per day/overnight. Valet parking is $20 per day/overnight.

MEETING LOCATION

Natcher Conference Center
National Institute of Health, Building 45
Bethesda, MD 20892
 
The meeting will be held at the Natcher Conference Center (Building 45) on the National Institutes of Health (NIH) Campus in Bethesda, Maryland. For a map, general information, and directions to and around the NIH Campus, visit: http://parking.nih.gov/visitor_access_map.htm .

NIH Security

The NIH, like all federal government facilities, has instituted security measures to ensure the safety of NIH employees, patients, and visitors. The national threat advisory level, determined by the Department of Homeland Security ( http://www.whitehouse.gov/homeland/ ), currently is yellow (elevated).

Perimeter Security

All visitor vehicles, including taxicabs, hotel and airport shuttles, delivery trucks, and vans will be inspected before being allowed on campus. Visitors will be asked to show one (1) form of identification (a government-issued photo ID: driver's license, passport, green card, etc.) and to state the purpose of their visit. Be sure to allow at least 15-20 minutes for this vehicle inspection procedure.

Building Security

Due to the checking of IDs at the perimeter, employees and visitors will not be required to show their ID again to gain access to the majority of buildings on the NIH Campus during the normal business day.
 
Employees and visitors should continue to wear their identification prominently at all times while on campus.
 
Guards will remain at certain buildings to address specific program requirements, such as sensitive research and safety concerns. At building entrances where guards are posted:
  • Employees must show a DHHS-issued photo ID (for example, your NIH-issued ID badge).
  • Visitors may be required to log-in, wear a visitor's pass, and be escorted by an employee through the building.
  • Visitors may be required to pass through a metal detector and have bags, backpacks, or purses inspected or x-rayed as they enter buildings.
  • Security staff will confiscate any suspicious or potentially dangerous materials. U.S. code prohibits bringing any dangerous weapons onto federal property, including anything with a blade longer than 2½ inches. Meeting participants may want to leave extra bags or personal materials at their hotel to minimize the time needed for inspection.

Weekday Campus Access

Visitors, including meeting attendees, patients, contractors, vendors, and delivery persons: All visitors must use the following entrances (see the Visitor Map at http://parking.nih.gov/visitor_access_map.htm ):
  • Rockville Pike at South Drive (Metro): Regular weekday schedule: Open 24 hours for inbound and outbound traffic.
  • Old Georgetown Road at Center Drive: This entrance is primarily for commercial vehicles and visitors.
Regular weekday schedule:
5:00 a.m. to 2:00 p.m. - Inbound traffic only
2:00 p.m. to 7:00 p.m. - Inbound and outbound traffic
7:00 p.m. to 5:00 a.m. - Closed to all traffic

Taking the Metrorail to the NIH Campus

The Metro System is clean and reliable. It operates from 5:00 a.m. to 12:00 midnight, Monday through Thursday; 5:00 a.m. to 3:00 a.m. on Fridays; 7:00 a.m. to 3:00 a.m. on Saturdays; and 7:00 a.m. to 12:00 midnight on Sundays. Each passenger must buy a farecard to travel in the system. Guides for purchasing farecards are posted on the vending machines in each station. Each Metro car features a complete color-coded map. Station attendants on duty at each station can provide additional information on request. Metro Web Site: http://www.wmata.com
 
The Natcher Conference Center is a 5-minute walk from the Medical Center station on the Red Line. The Natcher Building is located on Center Drive directly behind the Medical Center Stop. The station’s escalators come out on the NIH campus; upon exiting the escalator, proceed right, following the detour signs to Center Drive.

Driving Directions to NIH

From Points North and East:
Take I-95 South to I-495 West (Capital Beltway) toward Silver Spring. Follow I-495 West for 9 miles to Exit 34 (Bethesda/Wisconsin Avenue). Follow signs for Route 355 South and stay in the right lane. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 45.
 
From Points North and West:
Take I-270 South to I-495 East (Capital Beltway) toward Washington, DC. Stay in one of the three left lanes. Follow signs for Route 355 South, a left-lane exit, onto Wisconsin Avenue. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 45.
 
From Points South:
Take I-95 North to I-495 (Capital Beltway) toward Tyson's Corner/Rockville. Follow I-495 for 20 miles. Take Exit 34 (Bethesda/Wisconsin Avenue). Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 45.
 
From Baltimore/Washington International Thurgood Marshall Airport (BWI):
Take the Route 195 connector to I-95 South. Take I-95 South to I-495 West (Capital Beltway) toward Silver Spring. Follow I-495 West for 9 miles to Exit 34 (Bethesda/Wisconsin Avenue). Follow signs for Route 355 South and stay in the right lane. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 45.
 
From Washington Dulles International Airport (IAD):
Take the Dulles Access Road for approximately 13 miles to Exit 18. Move to the right on the Dulles Toll Road (Route 267) and take Exit 18. Stay left on the ramp for Bethesda/Baltimore, and proceed toward Bethesda (I-495). Continue approximately 9 miles on I-495. Stay on I-495 at the I-495/I-270 split (bear right). Take Exit 34 (Wisconsin Avenue South/Route 355) toward Bethesda. Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to
Building 45.
 
From Ronald Reagan Washington National Airport (DCA):
Take the George Washington Parkway North for 12 miles to I-495 toward Maryland (Capital Beltway). Take Exit 34 (Bethesda/Wisconsin Avenue). Travel approximately 1 mile and turn right at the light onto South Drive. Pass through NIH security and follow the signs to Building 45.

Parking

Parking on the NIH campus is limited and is $12 per day in the visitor lots.

Minutes

​Minutes are currently unavailable.

Attendees

​​Attendees are currently unavailable.

Abstracts

​​Abstracts are currently unavailable.

Location

Line
  • Lister Hill Auditorium
  • Building 38A, NIH Campus
  • MD 20892
Webinar

Contacts

Line For questions concerning general program content, contact:
Tracy L. Rankin, Ph.D.
Program Director, Career Development and Training
Division of Kidney, Urologic and Hematologic Diseases
National Institute of Diabetes and Digestive and Kidney Diseases
Telephone: (301) 594-4748
Email: rankint@niddk.nih.gov

For questions concerning logistical information or registration, contact:
Michelle Watson
The Scientific Consulting Group, Inc.
Telephone: (301) 670-4990
Email: mwatson@scgcorp.com