Resource

Use of leptin for treating human lipoatrophy and method of determining predisposition to said treatment (U.S. Patent Application Number 20070099836)

Acronym: Not Available NIDDK Contact: tao@niddk.nih.gov Principal Investigator(s): Phillip Gorden

Description:

Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipoatrophy. Leptin is effective against conditions of lipoatrophy for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including subcutaneously and using gene therapy methods. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having a leptin level of approximately 4 ng/ml or less before treatment.

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