U.S. Department of Health and Human Services

Integrative Physiology Section

Kevin Hall, Chief

About the Section

The Integrative Physiology Section focuses on applying mathematical models to metabolism and body weight regulation.

Current Research 

Understanding the dynamics of human body weight change has important consequences for conditions such as obesity, diabetes, cardiovascular disease, starvation, and wasting syndromes such as anorexia nervosa and cancer cachexia. By using mathematical modeling to quantitatively integrate metabolism data with body weight and composition data, Dr. Kevin Hall's research aims to substantially improve our understanding of body weight regulation and develop practical tools for research and clinical use.
 
These tools are for use in adults only and are not intended to provide personal medical advice. NIDDK cannot provide a diagnosis or medical advice for an individual situation. A health care provider who has examined you and knows your medical history is the best person to provide that information. If you have specific questions about the information presented, concerns about individual health matters or body weight management, please consult your physician.
 
Please note: the Body Weight simulator model supersedes the research tools provided in the Computational modeling of human metabolism and body weight change and Modeling weight loss maintenance spreadsheets linked below.
  1. Body Weight Simulator

  2. Computational modeling of human metabolism and body weight change

  3. Modeling weight loss maintenance

    Dr. Hall recently proposed a mathematical model to calculate the changes of dietary energy intake and physical activity required to maintain a given body weight change and prevent weight regain. 

Should you have any accessibility issues with the tools on the pages above, please contact Dr. Hall directly by phone: 301-402-8248 or Email: Kevinh@niddk.nih.gov.

*You may need to download the free WinZip service​ to open the file.