U.S. Department of Health and Human Services

Laboratory of Cellular and Developmental Biology

Jurrien Dean, M.D., Chief


A selection of recent and significant publications can be viewed below.

Dale RK, Matzat LH, Lei EP. metaseq: a Python package for integrative genome-wide analysis reveals relationships between chromatin insulators and associated nuclear mRNA. . [Full Text/Abstract]
Jardine D, Emond M, Meert KL, Harrison R, Carcillo JA, Anand KJ, Berger J, Newth CJ, Willson DF, Nicholson C, Dean JM, Zimmerman JJ, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. A Single Nucleotide Polymorphism in the Corticotropin Receptor Gene Is Associated With a Blunted Cortisol Response During Pediatric Critical Illness. . [Full Text/Abstract]
Welsh LC, Dunlop AW, McGovern T, McQuaid D, Dean JA, Gulliford SL, Bhide SA, Harrington KJ, Nutting CM, Newbold KL. Neurocognitive Function After (Chemo)-Radiotherapy for Head and Neck Cancer. . [Full Text/Abstract]
Chen ZX, Sturgill D, Qu J, Jiang H, Park S, Boley N, Suzuki AM, Fletcher AR, Plachetzki DC, FitzGerald PC, Artieri CG, Atallah J, Barmina O, Brown JB, Blankenburg KP, Clough E, Dasgupta A, Gubbala S, Han Y, Jayaseelan JC, Kalra D, Kim YA, Kovar CL, Lee SL, Li M, Malley JD, Malone JH, Mathew T, Mattiuzzo NR, Munidasa M, Muzny DM, Ongeri F, Perales L, Przytycka TM, Pu LL, Robinson G, Thornton RL, Saada N, Scherer SE, Smith HE, Vinson C, Warner CB, Worley KC, Wu YQ, Zou X, Cherbas P, Kellis M, Eisen MB, Piano F, Kionte K, Fitch DH, Sternberg PW, Cutter AD, Duff MO, Hoskins RA, Graveley BR, Gibbs RA, Bickel PJ, Kopp A, Carninci P, Celniker SE, Oliver B, Richards S. Comparative validation of the D. melanogaster modENCODE transcriptome annotation.Genome Res. ; 24 (7; 24) :1209-23. [Full Text/Abstract]
Chen L, Ge Q, Tjin G, Alkhouri H, Deng L, Brandsma CA, Adcock I, Timens W, Postma D, Burgess JK, Black JL, Oliver BG. Effects of cigarette smoke extract on human airway smooth muscle cells in COPD. . [Full Text/Abstract]
McCann FE, Perocheau DP, Ruspi G, Blazek K, Davies ML, Feldmann M, Dean JL, Stoop AA, Williams RO. Selective TNFR1 blockade is anti-inflammatory and reveals an immunoregulatory role for TNFR2. . [Full Text/Abstract]
Whitworth C, Oliver B. Flipping the doublesex switch with a piRNA.Genome Biol. ; 15 (6; 15) :118. [Full Text/Abstract]
Isnard Bagnis C, Crepaldi C, Dean J, Goovaerts T, Melander S, Nilsson EL, Prieto-Velasco M, Trujillo C, Zambon R, Mooney A. Quality standards for predialysis education: results from a consensus conference. . [Full Text/Abstract]
Avella MA, Baibakov B, Dean J. A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans.J Cell Biol. 2014 Jun 23; 205 (2014 Jun 23; 6; 205) :801-9. [Full Text/Abstract]
Boisa N, Elom N, Dean JR, Deary ME, Bird G, Entwistle JA. Development and application of an inhalation bioaccessibility method (IBM) for lead in the PM10 size fraction of soil.Environ Int. ; 70C (70C) :132-142. [Full Text/Abstract]
Ly DV, Oliver BG. Do We Really Need to Keep Redesigning β2-Agonists for the Management of Asthma? . [Full Text/Abstract]
Warholak TL, Hilgaertner JW, Dean JL, Taylor AM, Hines LE, Hurwitz J, Brown M, Malone DC. Evaluation of an educational program on deciphering heterogeneity for medical coverage decisions.J Manag Care Pharm. ; 20 (20; 6) :566-73. [Full Text/Abstract]
Dayan PS, Holmes JF, Atabaki S, Hoyle J Jr, Tunik MG, Lichenstein R, Alpern E, Miskin M, Kuppermann N, Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN). Association of traumatic brain injuries with vomiting in children with blunt head trauma.Ann Emerg Med. ; 63 (6; 63) :657-65. [Full Text/Abstract]
Badaki-Makun O, Scott JP, Panepinto JA, Casper TC, Hillery CA, Dean JM, Brousseau DC, Pediatric Emergency Care Applied Research Network (PECARN) Magnesium in Sickle Cell Crisis (MAGiC) Study Group. Intravenous magnesium for pediatric sickle cell vaso-occlusive crisis: Methodological issues of a randomized controlled trial.Pediatr Blood Cancer. ; 61 (6; 61) :1049-54. [Full Text/Abstract]
Pollack MM, Holubkov R, Funai T, Clark A, Moler F, Shanley T, Meert K, Newth CJ, Carcillo J, Berger JT, Doctor A, Berg RA, Dalton H, Wessel DL, Harrison RE, Dean JM, Jenkins TL. Relationship Between the Functional Status Scale and the Pediatric Overall Performance Category and Pediatric Cerebral Performance Category Scales. . [Full Text/Abstract]
Alkhouri H, Rumzhum NN, Rahman MM, FitzPatrick M, de Pedro M, Oliver BG, Bourke JE, Ammit AJ. TLR2 activation causes tachyphylaxis to β2 -agonists in vitro and ex vivo: modeling bacterial exacerbation. . [Full Text/Abstract]
Serefoglu EC, McMahon CG, Waldinger MD, Althof SE, Shindel A, Adaikan G, Becher EF, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO. An Evidence-Based Unified Definition of Lifelong and Acquired Premature Ejaculation: Report of the Second International Society for Sexual Medicine Ad Hoc Committee for the Definition of Premature Ejaculation. . [Full Text/Abstract]
Althof SE, McMahon CG, Waldinger MD, Serefoglu EC, Shindel AW, Adaikan PG, Becher E, Dean J, Giuliano F, Hellstrom WJ, Giraldi A, Glina S, Incrocci L, Jannini E, McCabe M, Parish S, Rowland D, Segraves RT, Sharlip I, Torres LO. An Update of the International Society of Sexual Medicine's Guidelines for the Diagnosis and Treatment of Premature Ejaculation (PE). . [Full Text/Abstract]
Popma JJ, Adams DH, Reardon MJ, Yakubov SJ, Kleiman NS, Heimansohn D, Hermiller J Jr, Hughes GC, Harrison JK, Coselli J, Diez J, Kafi A, Schreiber T, Gleason TG, Conte J, Buchbinder M, Deeb GM, Carabello B, Serruys PW, Chenoweth S, Oh JK, CoreValve United States Clinical Investigators. Transcatheter aortic valve replacement using a self-expanding bioprosthesis in patients with severe aortic stenosis at extreme risk for surgery.J Am Coll Cardiol. ; 63 (19; 63) :1972-81. [Full Text/Abstract]
Jaffar J, Unger S, Corte TJ, Keller M, Wolters PJ, Richeldi L, Cerri S, Prêle CM, Hansbro PM, Argraves WS, Oliver RA, Oliver BG, Black JL, Burgess JK. Fibulin-1 predicts disease progression in patients with idiopathic pulmonary fibrosis. . [Full Text/Abstract]
Dean JH, Woznicki EM, O'Gara P, Montgomery DG, Trimarchi S, Myrmel T, Pyeritz RE, Harris KM, Suzuki T, Braverman AC, Hughes GC, Kline-Rogers E, Nienaber CA, Isselbacher EM, Eagle KA, Bossone E. Cocaine Related Aortic Dissection: Lessons from the International Registry of Acute Aortic Dissection. . [Full Text/Abstract]
Zeng Y, Feng F, Medová H, Dean J, Kobližek M. Functional type 2 photosynthetic reaction centers found in the rare bacterial phylum Gemmatimonadetes. . [Full Text/Abstract]
Avella M, Baibakov B, and Dean J. A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans.J. Cell Biol., in press. May 12, 2014 (May 12, 2014) . [Full Text/Abstract]
Del Giudice E, Macca M, Imperati F, D'Amico A, Parent P, Pasquier L, Layet V, Lyonnet S, Stamboul-Darmency V, Thauvin-Robinet C, Franco B, Oral-Facial-Digital Type I (OFD1) Collaborative Group. CNS involvement in OFD1 syndrome: a clinical, molecular, and neuroimaging study.Orphanet J Rare Dis. ; 9 (9) :74. [Full Text/Abstract]
Adams DH, Popma JJ, Reardon MJ, Yakubov SJ, Coselli JS, Deeb GM, Gleason TG, Buchbinder M, Hermiller J Jr, Kleiman NS, Chetcuti S, Heiser J, Merhi W, Zorn G, Tadros P, Robinson N, Petrossian G, Hughes GC, Harrison JK, Conte J, Maini B, Mumtaz M, Chenoweth S, Oh JK, U.S. CoreValve Clinical Investigators. Transcatheter aortic-valve replacement with a self-expanding prosthesis.N Engl J Med. ; 370 (19; 370) :1790-8. [Full Text/Abstract]
Dean J, Claas B. African clawed toads (Xenopus laevis) sense the distance of lateral line stimuli. . [Full Text/Abstract]
Rankin BL, Buffo SK, Dean JC. A Neuromechanical Strategy for Mediolateral Foot Placement in Walking Humans. . [Full Text/Abstract]
Chamberlain JM, Okada P, Holsti M, Mahajan P, Brown KM, Vance C, Gonzalez V, Lichenstein R, Stanley R, Brousseau DC, Grubenhoff J, Zemek R, Johnson DW, Clemons TE, Baren J, Pediatric Emergency Care Applied Research Network (PECARN). Lorazepam vs diazepam for pediatric status epilepticus: a randomized clinical trial.JAMA. ; 311 (16; 311) :1652-60. [Full Text/Abstract]
Denawaka CJ, Fowlis IA, Dean JR. Evaluation and application of static headspace-multicapillary column-gas chromatography-ion mobility spectrometry for complex sample analysis.J Chromatogr A. ; 1338 (1338) :136-48. [Full Text/Abstract]
Lafeuille MH, Dean J, Carter V, Duh MS, Fastenau J, Dirani R, Lefebvre P. Systematic Review of Long-Acting Injectables versus Oral Atypical Antipsychotics on Hospitalization in Schizophrenia. . [Full Text/Abstract]