U.S. Department of Health and Human Services

Genomic Structure and Function Section

Anthony V. Furano, M.D., Chief


A selection of recent and significant publications can be viewed below.

Chen J, Miller BF, Furano AV. Repair of naturally occurring mismatches can induce mutations in flanking DNA.Elife (Cambridge). ; 3 (3) :e02001. [Full Text/Abstract]
Callahan KE, Hickman AB, Jones CE, Ghirlando R, Furano AV. Polymerization and nucleic acid-binding properties of human L1 ORF1 protein.Nucleic Acids Res. 2012 Jan; 40 (40; 2; 2012 Jan) :813-27. [Full Text/Abstract]
Walser JC, Furano AV. The mutational spectrum of non-CpG DNA varies with CpG content.Genome Res. 2010 Jul; 20 (20; 7; 2010 Jul) :875-82. [Full Text/Abstract]
Walser JC, Ponger L, Furano AV. CpG dinucleotides and the mutation rate of non-CpG DNA.Genome Res. 2008 Sep; 18 (9; 2008 Sep; 18) :1403-14. [Full Text/Abstract]
Boissinot S, Davis J, Entezam A, Petrov D, Furano AV. Fitness cost of LINE-1 (L1) activity in humans.Proc Natl Acad Sci U S A. 2006 Jun 20; 103 (25; 2006 Jun 20; 103) :9590-4. [Full Text/Abstract]
Boissinot S, Entezam A, Young L, Munson PJ, Furano AV. The insertional history of an active family of L1 retrotransposons in humans.Genome Res. 2004 Jul; 14 (2004 Jul; 14; 7) :1221-31. [Full Text/Abstract]
Furano AV, Duvernell DD, Boissinot S. L1 (LINE-1) retrotransposon diversity differs dramatically between mammals and fish.Trends Genet. 2004 Jan; 20 (20; 2004 Jan; 1) :9-14. [Full Text/Abstract]
Eickbush TH, Furano AV. Fruit flies and humans respond differently to retrotransposons.Curr Opin Genet Dev. 2002 Dec; 12 (6; 12; 2002 Dec) :669-74. [Full Text/Abstract]