U.S. Department of Health and Human Services

Clinical Research Section

T. Jake Liang, M.D., Chief

Section Staff


Photo of T. Jake Liang, M.D. 

T. Jake Liang, M.D., Chief, Liver Diseases Branch

M.D. – Harvard Medical School, Boston, MA
Internal Medicine Residency – New York University/Bellevue Hospital Center, New York, NY
Gastroenterology Fellowship – Massachusetts General Hospital, Boston, MA

Photo of Edward Doo, M.D.
Edward Doo, M.D., Director, Liver Diseases Research Program

M.D. – Cornell University Medical College, New York, NY
Internal Medicine Residency – The New York Hospital-Cornell Medical Center, New York, NY

 

Photo of Marc Ghany, M.D.

Marc Ghany, M.D., Staff Clinician, Liver Diseases Branch

M.D. – Royal College of Surgeons in Ireland, Dublin, Ireland
Internal Medicine Residency – Hospital of St. Raphael, New Haven, CT
Gastroenterology Fellowship – Tulane University School of Medicine, New Orleans, LA
Liver Diseases Fellowship – NIDDK, Bethesda, MD
M.H.Sc. – Duke University School of Medicine, Durham, NC

Photo of Theo Heller, M.D.

Theo Heller, M.D., Tenure Track Clinical Investigator, Liver Diseases Branch

M.D. – University of Witwatersrand Medical school
Internal Medicine Residency – Georgetown University Hospital
Viral Hepatitis Fellowship – NIAID, Bethesda, MD
Gastroenterology Fellowship – University of Maryland School of Medicine
Liver Diseases Fellowship – NIDDK, Bethesda, MD

Photo of Jay Hoofnagle, M.D.

Jay ​Hoofnagle, M.D., Director, Liver Disease Research Branch

M.D. – Yale University School of Medicine, New Haven, CT
Internal Medicine Residency – University of Virginia Health System, Charlottesville, VA
Internal Medicine Residency – VA Medical Center, Washington, DC
Gastroenterology Fellowship – VA Medical Center, Washington, DC

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Christopher Koh, M.D. M.H.Sc., Staff Clinician, Liver Diseases Branch

M.D. – Saba University School of Medicine, Netherlands-Antilles
M.H.Sc. - Duke University School of Medicine, Durham, NC
Internal Medicine Residency – Harbor Hospital, Baltimore, MD
Liver Diseases Fellowship – NIDDK, Bethesda, MD
Gastroenterology Fellowship – University of Maryland/NIH Scholars Program, Baltimore, MD & Bethesda, MD

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Yaron Rotman, M.D., Assistant Clinical Investigator, Liver Diseases Branch

M.D. – Hebrew University Hadassah Medical School, Jerusalem, Israel
M.Sc. – Hebrew University Hadassah Medical School, Jerusalem, Israel
Internal Medicine Residency – Rabin Medical Center, Petach-Tiqwa, Israel
Gastroenterology Fellowship – Rabin Medical Center, Petach-Tiqwa, Israel
Liver Diseases Fellowship – NIDDK, Bethesda, MD

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Averell H. Sherker, M.D., Scientific Advisor, Viral Hepatitis and Liver Diseases

M.D. – Queens University Faculty of Health Sciences, Kingston, Canada
Internal Medicine Residency – Mt. Sinai Hosptial University, Toronto, Canada
Gastroenterology Fellowship – University of Toronto, Ontario, Canada
Liver Diseases Fellowship – Stanford University, Stanford, CA

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Niharika​ Samala, M.D., Clinical Fellow

I was born and brought up in India. My pursuit for training in clinical research and liver diseases brought me to liver diseases branch at NIH.

My research interests include hepatitis E, role of immunity in liver disease and Non-alcoholic steatohepatitis (NASH). Hepatitis E has been known to be a disease of the non-developed world until a recent surge in reports of cases in developed countries. Appearance of chronic hepatitis E in immunocompromised hosts raises the need for treatment. My research aims at understanding the clinical impact of hepatitis E infection in the US. It is believed that it is not always the environmental trigger that results in disease, it is the host’s response to them that manifests as disease. I am interested in understanding the role of immunity in liver disease. I am particularly interested in liver disease in stem cell transplant patients. I am excited by the complexity of my question in this patient population. NASH interests me for several reasons. It affects a significant demographic of the developed countries. Its etiopathogenesis is not completely understood. We do not have a potent pharmacologic therapy yet.​

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Hawwa Alao, M.D., Clinical Fellow

The liver is unique not only for its regenerative ability. It supports almost every organ and is vital to human survival. It plays significant roles in host defense and immunity, detoxification, metabolism and protein synthesis. As it receives dual blood supply from the gut and systemic circulation, it is always exposed and prone to many diseases. These characteristics, amongst others not only fascinate me but also continue to be of great intellectual interest. 

My research interest lies in how different disease states affect the physiological and immunological function of the liver leading to chronic liver disease. I am currently studying Sickle Cell liver disease as a model to identify biological and clinical factors that predict progression and regression of liver disease. I am also looking at how chemotherapeutic agents used in treating lymphoma affect the liver. My goal is to be able to apply my research findings to liver diseases around the world.

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Yun Ju Kim, M.D., Clinical Fellow

My research interests focuses on two areas: Firstly, long-term hepatic complications from valvular heart disease and secondly chronic hepatitis C. Patients with congenital heart disease offer a window into unique and diverse hepatic complications. Hepatic complications of congenital heart disease are increasing as patients have increasing survival time. The recognition, evaluation and treatment of liver disease are important in preventing increased mortality associated with hepatic complications. Secondly, I am also interested in the treatment of hepatitis C. Specifically, I am intrigued by the genetic variations in patients with hepatitis C possibly influencing pathogenesis and response to treatment.


Etzion Ohad, Clinical Fellow

Etzion Ohad, Clinical Fellow

Progression to cirrhosis in patients chronically infected with HCV marks a turning point in disease evolution. Accumulating evidence suggests that gut microbial products translocating across the intestinal wall to the portal blood system may also reach the systemic circulation inducing a global proinflammatory state. My main research interest is in elucidating the mechanisms responsible for this phenomenon, and understanding its contribution to the progression of liver cirrhosis and its complications. Other research interests of mine include, characterizing immune response patterns to HBV vaccine in patients receiving immunosuppressive medications, and understanding the differential metabolic pathways dominating fasting and fed states in NAFLD patients versus healthy controls. 


Darlina Sosa, Patient Care Coordinator

 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 16142
T: 301-435-6121
F: 301-435-9160


Nancy Fryzek, BSN, RN, Research Nurse, Specialist
 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 1614
Bethesda, MD 20892
T: 301-435-6122
F: 301-435-9160


Vanessa Haynes-Williams, BSN, RN, Research Nurse, Specialist

 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 1614
Bethesda, MD 20892
T: 301-451-7007
F: 301-435-9160


Elenita M. Rivera, BSN, RN, Research Nurse, Specialist

 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 1614
Bethesda, MD 20892
T: 301-435-6125
F: 301-451-9160


Nevitt, Morris, BSN, RN, Research Nurse, Specialist

 

10 Center Drive, Bldg: 10 CRC, Rm: 4-5722, MSC 1614
Bethesda, MD 20892
T: 301-496-1665
F: 301-435-9160​

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