U.S. Department of Health and Human Services

Molecular and Clinical Hematology Branch

Griffin P. Rodgers, M.D., M.A.C.P, Chief

​Publications

A selection of recent and significant publications can be viewed below.

Publications
Kumkhaek C, Aerbajinai W, Liu W, Zhu J, Uchida N, Kurlander R, Hsieh MM, Tisdale JF, Rodgers GP. MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway.Blood. 2013 Apr 18; 121 (121; 16; 2013 Apr 18) :3216-27. [Full Text/Abstract]
Kumkhaek C, Liu W, Rodgers GP. Identification and characterization of novel full-length cDNAs expressed during hematopoietic lineage-specific differentiation of cultured human peripheral blood mononuclear cells.Blood Cells Mol. Dis. 2013 Mar; 50 (2013 Mar; 50; 3) :154-5. [Full Text/Abstract]
Liu L, Aerbajinai W, Ahmed SM, Rodgers GP, Angers S, Parent CA. Radil controls neutrophil adhesion and motility through β2-integrin activation.Mol. Biol. Cell. 2012 Dec; 23 (2012 Dec; 23; 24) :4751-65. [Full Text/Abstract]
Liu W, Yan M, Liu Y, McLeish KR, Coleman WG Jr, Rodgers GP. Olfactomedin 4 inhibits cathepsin C-mediated protease activities, thereby modulating neutrophil killing of Staphylococcus aureus and Escherichia coli in mice.J. Immunol. 2012 Sep 1; 189 (189; 5; 2012 Sep 1) :2460-7. [Full Text/Abstract]
Aerbajinai W, Liu L, Chin K, Zhu J, Parent CA, Rodgers GP. Glia maturation factor-γ mediates neutrophil chemotaxis.J. Leukoc. Biol. 2011 Sep; 90 (2011 Sep; 3; 90) :529-38. [Full Text/Abstract]
Chen L, Li H, Liu W, Zhu J, Zhao X, Wright E, Cao L, Ding I, Rodgers GP. Olfactomedin 4 suppresses prostate cancer cell growth and metastasis via negative interaction with cathepsin D and SDF-1.Carcinogenesis. 2011 Jul; 32 (32; 7; 2011 Jul) :986-94. [Full Text/Abstract]
Zhu J, Chin K, Aerbajinai W, Trainor C, Gao P, Rodgers GP. Recombinant erythroid Kruppel-like factor fused to GATA1 up-regulates delta- and gamma-globin expression in erythroid cells.Blood. 2011 Mar 17; 117 (2011 Mar 17; 117; 11) :3045-52. [Full Text/Abstract]
Liu W, Lee HW, Liu Y, Wang R, Rodgers GP. Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis.Blood. 2010 Dec 2; 116 (2010 Dec 2; 23; 116) :4938-47. [Full Text/Abstract]
Liu W, Yan M, Liu Y, Wang R, Li C, Deng C, Singh A, Coleman WG Jr, Rodgers GP. Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection.Proc. Natl. Acad. Sci. U.S.A. 2010 Jun 15; 107 (107; 2010 Jun 15; 24) :11056-61. [Full Text/Abstract]
Hsieh MM, Tisdale JF, Rodgers GP, Young NS, Trimble EL, Little RF. Neutrophil count in African Americans: lowering the target cutoff to initiate or resume chemotherapy?J. Clin. Oncol. 2010 Apr 1; 28 (2010 Apr 1; 28; 10) :1633-7. [Full Text/Abstract]
Hsieh MM, Kang EM, Fitzhugh CD, Link MB, Bolan CD, Kurlander R, Childs RW, Rodgers GP, Powell JD, Tisdale JF. Allogeneic hematopoietic stem-cell transplantation for sickle cell disease.N. Engl. J. Med. 2009 Dec 10; 361 (2009 Dec 10; 24; 361) :2309-17. [Full Text/Abstract]
Aerbajinai W, Zhu J, Kumkhaek C, Chin K, Rodgers GP. SCF induces gamma-globin gene expression by regulating downstream transcription factor COUP-TFII.Blood. 2009 Jul 2; 114 (114; 2009 Jul 2; 1) :187-94. [Full Text/Abstract]
Chin KL, Aerbajinai W, Zhu J, Drew L, Chen L, Liu W, Rodgers GP. The regulation of OLFM4 expression in myeloid precursor cells relies on NF-kappaB transcription factor.Br. J. Haematol. 2008 Nov; 143 (3; 2008 Nov; 143) :421-32. [Full Text/Abstract]
Kumkhaek C, Taylor JG 6th, Zhu J, Hoppe C, Kato GJ, Rodgers GP. Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia.Br. J. Haematol. 2008 Apr; 141 (2008 Apr; 2; 141) :254-9. [Full Text/Abstract]
Liu W, Liu Y, Zhu J, Wright E, Ding I, Rodgers GP. Reduced hGC-1 protein expression is associated with malignant progression of colon carcinoma.Clin. Cancer Res. 2008 Feb 15; 14 (2008 Feb 15; 14; 4) :1041-9. [Full Text/Abstract]
Aerbajinai W, Zhu J, Gao Z, Chin K, Rodgers GP. Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis.Blood. 2007 Oct 15; 110 (8; 2007 Oct 15; 110) :2864-71. [Full Text/Abstract]
Hsieh MM, Linde NS, Wynter A, Metzger M, Wong C, Langsetmo I, Lin A, Smith R, Rodgers GP, Donahue RE, Klaus SJ, Tisdale JF. HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques.Blood. 2007 Sep 15; 110 (6; 110; 2007 Sep 15) :2140-7. [Full Text/Abstract]
Chen L, Gao Z, Zhu J, Rodgers GP. Identification of CD13+CD36+ cells as a common progenitor for erythroid and myeloid lineages in human bone marrow.Exp. Hematol. 2007 Jul; 35 (2007 Jul; 35; 7) :1047-55. [Full Text/Abstract]
Hsieh MM, Everhart JE, Byrd-Holt DD, Tisdale JF, Rodgers GP. Prevalence of neutropenia in the U.S. population: age, sex, smoking status, and ethnic differences.Ann. Intern. Med. 2007 Apr 3; 146 (146; 7; 2007 Apr 3) :486-92. [Full Text/Abstract]
Park DM, Zhuang Z, Chen L, Szerlip N, Maric I, Li J, Sohn T, Kim SH, Lubensky IA, Vortmeyer AO, Rodgers GP, Oldfield EH, Lonser RR. von Hippel-Lindau disease-associated hemangioblastomas are derived from embryologic multipotent cells.PLoS Med. 2007 Feb; 4 (2; 4; 2007 Feb) :e60. [Full Text/Abstract]
Chen L, Zhang H, Shi Y, Chin KL, Tang DC, Rodgers GP. Identification of key genes responsible for cytokine-induced erythroid and myeloid differentiation and switching of hematopoietic stem cells by RAGE.Cell Res. 2006 Dec; 16 (16; 2006 Dec; 12) :923-39. [Full Text/Abstract]
Shi Y, Chen L, Liotta LA, Wan HH, Rodgers GP. Glia maturation factor gamma (GMFG): a cytokine-responsive protein during hematopoietic lineage development and its functional genomics analysis.Genomics Proteomics Bioinformatics. 2006 Aug; 4 (2006 Aug; 4; 3) :145-55. [Full Text/Abstract]
Liu W, Chen L, Zhu J, Rodgers GP. The glycoprotein hGC-1 binds to cadherin and lectins.Exp. Cell Res. 2006 Jun 10; 312 (2006 Jun 10; 10; 312) :1785-97. [Full Text/Abstract]
Kramer BS, Wilentz J, Alexander D, Burklow J, Friedman LM, Hodes R, Kirschstein R, Patterson A, Rodgers G, Straus SE. Getting it right: being smarter about clinical trials.PLoS Med. 2006 Apr; 3 (6; 3; 2006 Apr) :e144. [Full Text/Abstract]
Zhuang Z, Huang S, Kowalak JA, Shi Y, Lei J, Furuta M, Lee YS, Lubensky IA, Rodgers GP, Cornelius AS, Weil RJ, Teh BT, Vortmeyer AO. From tissue phenotype to proteotype: sensitive protein identification in microdissected tumor tissue.Int. J. Oncol. 2006 Jan; 28 (2006 Jan; 28; 1) :103-10. [Full Text/Abstract]
Zoueva OP, Garrett LJ, Bodine D, Rodgers GP. BP1 motif in the human beta-globin promoter affects beta-globin expression during embryonic/fetal erythropoiesis in transgenic mice bearing the human beta-globin gene.Blood Cells Mol. Dis. 2008 Nov-Dec; 41 (2008 Nov-Dec; 41; 3) :244-51. [Full Text/Abstract]