U.S. Department of Health and Human Services

Metabolic Diseases Branch

Lee S. Weinstein, M.D., Chief


A selection of recent and significant publications can be viewed below.

Chen LY, Lopez FL, Gottesman RF, Huxley RR, Agarwal SK, Loehr L, Mosley T, Alonso A. Atrial Fibrillation and Cognitive Decline-The Role of Subclinical Cerebral Infarcts: The Atherosclerosis Risk in Communities Study. . [Full Text/Abstract]
Sinner MF, Stepas KA, Moser CB, Krijthe BP, Aspelund T, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Vasan RS, Wang TJ, Agarwal SK, McManus DD, Franco OH, Yin X, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Astor BC, Ballantyne CM, Hoogeveen RC, Arai AE, Soliman EZ, Ellinor PT, Stricker BH, Gudnason V, Heckbert SR, Pencina MJ, Benjamin EJ, Alonso A. B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies. . [Full Text/Abstract]
Agarwal SK, Kriel RL, Cloyd JC, Coles LD, Scherkenbach LA, Tobin MH, Krach LE. A Pilot Study Assessing Pharmacokinetics and Tolerability of Oral and Intravenous Baclofen in Healthy Adult Volunteers. . [Full Text/Abstract]
Marx S. Uncoupling of Secretion from Size in Some Hormone Secretory Tissues. :jc20142113. [Full Text/Abstract]
Rodriguez CJ, Swett K, Agarwal SK, Folsom AR, Fox ER, Loehr LR, Ni H, Rosamond WD, Chang PP. Systolic Blood Pressure Levels Among Adults With Hypertension and Incident Cardiovascular Events: The Atherosclerosis Risk in Communities Study. . [Full Text/Abstract]
Alonso A, Misialek JR, Amiin MA, Hoogeveen RC, Chen LY, Agarwal SK, Loehr LR, Soliman EZ, Selvin E. Circulating levels of liver enzymes and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities cohort. . [Full Text/Abstract]
Lutsey PL, Alonso A, Selvin E, Pankow JS, Michos ED, Agarwal SK, Loehr LR, Eckfeldt JH, Coresh J. Fibroblast Growth Factor-23 and Incident Coronary Heart Disease, Heart Failure, and Cardiovascular Mortality: The Atherosclerosis Risk In Communities Study.J Am Heart Assoc. ; 3 (3) . [Full Text/Abstract]
Huxley RR, Misialek JR, Agarwal SK, Loehr LR, Soliman EZ, Chen LY, Alonso A. Physical Activity, Obesity, Weight Change and Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study. . [Full Text/Abstract]
Mosalpuria K, Agarwal SK, Yaemsiri S, Pierre-Louis B, Saba S, Alvarez R, Russell SD. Outpatient management of heart failure in the United States, 2006-2008.Tex Heart Inst J. ; 41 (41; 3) :253-61. [Full Text/Abstract]
Muthuvel G, Tevis SE, Liepert AE, Agarwal SK, Kennedy GD. A composite index for predicting readmission following emergency general surgery.J Trauma Acute Care Surg. ; 76 (76; 6) :1467-72. [Full Text/Abstract]
Sinha P, Aarnisalo P, Chubb R, Ono N, Fulzele K, Selig M, Saeed H, Chen M, Weinstein LS, Divieti Pajevic P, Kronenberg HM, Wu JY. Loss of Gs α Early in the Osteoblast Lineage Favors Adipogenic Differentiation of Mesenchymal Progenitors and Committed Osteoblast Precursors. . [Full Text/Abstract]
Gupta U, Mir SS, Srivastava A, Garg N, Agarwal SK, Pande S, Mittal B. Signal Transducers and Activators of Transcription (STATs) Gene Polymorphisms Related With Susceptibility to Rheumatic Heart Disease in North Indian Population. . [Full Text/Abstract]
Agarwal SK. Single antiplatelet therapy after percutaneous coronary intervention in patients allergic to aspirin. . [Full Text/Abstract]
Chagin AS, Vuppalapati KK, Kobayashi T, Guo J, Hirai T, Chen M, Offermanns S, Weinstein LS, Kronenberg HM. G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes.Nat Commun. ; 5 (5) :3673. [Full Text/Abstract]
Alimperti S, You H, George T, Agarwal SK, Andreadis ST. Cadherin-11 regulates mesenchymal stem cell differentiation into smooth muscle cells and development of contractile function in vivo. . [Full Text/Abstract]
Wang Z, Fan M, Candas D, Zhang TQ, Qin L, Eldridge A, Wachsmann-Hogiu S, Ahmed KM, Chromy BA, Nantajit D, Duru N, He F, Chen M, Finkel T, Weinstein LS, Li JJ. Cyclin B1/Cdk1 Coordinates Mitochondrial Respiration for Cell-Cycle G2/M Progression. . [Full Text/Abstract]
Rathore SS, Agarwal SK, Pande S, Singh SK, Mittal T, Mittal B. CYP4F2 1347 G > A & GGCX 12970 C > G polymorphisms: frequency in north Indians & their effect on dosing of acenocoumarol oral anticoagulant.Indian J Med Res. ; 139 (139; 4) :572-578. [Full Text/Abstract]
Wu M, Pedroza M, Lafyatis R, George AT, Mayes MD, Assassi S, Tan FK, Brenner MB, Agarwal SK. Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis.Arthritis Rheumatol. ; 66 (66; 4) :1010-21. [Full Text/Abstract]
Toor K, Wessels JM, Agarwal SK, Leyland N, Foster WG. Clinical markers of endometriosis: have we been too quick to judge?Med Hypotheses. ; 82 (82; 4) :493-501. [Full Text/Abstract]
Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller-Nurasyid M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kääb S, Mahida S, Kathiresan S, Kubo M, Launer LJ, Macfarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor KD, Tomaschitz A, Tsunoda T, Uitterlinden AG, Van Wagoner DR, Völker U, Völzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, März W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT. Novel genetic markers associate with atrial fibrillation risk in europeans and Japanese.J Am Coll Cardiol. ; 63 (12; 63) :1200-10. [Full Text/Abstract]
Riley JL 3rd, Gordan VV, Hudak-Boss SE, Fellows JL, Rindal DB, Gilbert GH, National Dental Practice-Based Research Network Collaborative Group. Concordance between patient satisfaction and the dentist's view: findings from The National Dental Practice-Based Research Network.J Am Dent Assoc. ; 145 (145; 4) :355-62. [Full Text/Abstract]
Chethan S, Singh S, Nongsiej J, Rakesh H, Singh R, Kumar N, Agarwal S. IFN-τ Acts in a Dose-Dependent Manner on Prostaglandin Production by Buffalo Endometrial Stromal Cells Cultured in vitro. . [Full Text/Abstract]
Li J, Agarwal SK, Alonso A, Blecker S, Chamberlain AM, London SJ, Loehr LR, McNeill AM, Poole C, Soliman EZ, Heiss G. Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study.Circulation. ; 129 (9; 129) :971-80. [Full Text/Abstract]
Agarwal SK. Capsule commentary on Ursua et al., awareness, treatment and control of hypertension among Filipino immigrants.J Gen Intern Med. ; 29 (3; 29) :514. [Full Text/Abstract]
Singh S, Kapoor A, Agarwal SK, Pande S, Sinha A, Rai H. Differential Release Kinetics of Cardiac Biomarkers in Patients Undergoing Valve Replacement Surgery.J Card Surg. ; 29 (2; 29) :134-40. [Full Text/Abstract]
Sinha A, Bajpai J, Saini S, Bhatia D, Gupta A, Puraswani M, Dinda AK, Agarwal SK, Sopory S, Pandey RM, Hari P, Bagga A. Serum-soluble urokinase receptor levels do not distinguish focal segmental glomerulosclerosis from other causes of nephrotic syndrome in children.Kidney Int. ; 85 (85; 3) :649-58. [Full Text/Abstract]
Desai SS, Modali SD, Parekh VI, Kebebew E, Agarwal SK. GSK-3β protein phosphorylates and stabilizes HLXB9 protein in insulinoma cells to form a targetable mechanism of controlling insulinoma cell proliferation.J Biol Chem. ; 289 (289; 9) :5386-98. [Full Text/Abstract]
Pande S, Tewari P, Agarwal SK, Jain M, Phadke RV. Idiopathic bilateral segmental pulmonary artery aneurysm.Ann Thorac Surg. ; 97 (2; 97) :e33-5. [Full Text/Abstract]
van Bon L, Affandi AJ, Broen J, Christmann RB, Marijnissen RJ, Stawski L, Farina GA, Stifano G, Mathes AL, Cossu M, York M, Collins C, Wenink M, Huijbens R, Hesselstrand R, Saxne T, DiMarzio M, Wuttge D, Agarwal SK, Reveille JD, Assassi S, Mayes M, Deng Y, Drenth JP, de Graaf J, den Heijer M, Kallenberg CG, Bijl M, Loof A, van den Berg WB, Joosten LA, Smith V, de Keyser F, Scorza R, Lunardi C, van Riel PL, Vonk M, van Heerde W, Meller S, Homey B, Beretta L, Roest M, Trojanowska M, Lafyatis R, Radstake TR. Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis.N Engl J Med. ; 370 (370; 5) :433-43. [Full Text/Abstract]
Blecker S, Agarwal SK, Chang PP, Rosamond WD, Casey DE, Kucharska-Newton A, Radford MJ, Coresh J, Katz S. Quality of care for heart failure patients hospitalized for any cause.J Am Coll Cardiol. ; 63 (2; 63) :123-30. [Full Text/Abstract]