U.S. Department of Health and Human Services

Diabetes, Endocrinology, and Obesity Branch

Marc L. Reitman, M.D., Ph.D., Chief

​Publications

A selection of recent and significant publications can be viewed below.

Publications
Geil CR, Hayes DM, McClain JA, Liput DJ, Marshall SA, Chen KY, Nixon K. Alcohol and adult hippocampal neurogenesis: promiscuous drug, wanton effects. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Oct 3; 54 (2014 Oct 3; 54):103-13. [Full Text/Abstract]
Malaguarnera R, Chen KY, Kim TY, Dominguez JM, Voza F, Ouyang B, Vundavalli SK, Knauf JA, Fagin JA. Switch in Signaling Control of mTORC1 Activity After Oncoprotein Expression in Thyroid Cancer Cell Lines. J Clin Endocrinol Metab. 2014 Jul 16; 99 (2014 Jul 16; 99; 10):E1976-E1987. [Full Text/Abstract]
Chen KY, Cheng CJ, Yen CM, Tang P, Wang LC. Comparative studies on the proteomic expression patterns in the third- and fifth-stage larvae of Angiostrongylus cantonensis. Parasitol Res. 2014 Jul 16; 113 (113; 2014 Jul 16; 10):3591-600. [Full Text/Abstract]
Irving WL, Rupp D, McClure CP, Than LM, Titman A, Ball JK, Steinmann E, Bartenschlager R, Pietschmann T, Brown RJ. Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region. Antiviral Res. 2014 Jul 22; 110 (110; 2014 Jul 22):52-9. [Full Text/Abstract]
Rahman MM, Kim KH, Brown RJ, Bae IS, Park CG. PCDD and PCDF concentrations in a traffic tunnel environment. Sci Total Environ. 2014 Sep 15; 493 (493; 2014 Sep 15):773-80. [Full Text/Abstract]
Hung YN, Yang SY, Huang MC, Lung FW, Lin SK, Chen KY, Kuo CJ, Chen YY. Cancer incidence in people with affective disorder: nationwide cohort study in Taiwan, 1997-2010. Br J Psychiatry. 2014 Jun 26; 205 (205; 2014 Jun 26; 3):183-8. [Full Text/Abstract]
Lee JH, Lin YL, Hsu WH, Chen HY, Chang YC, Yu CJ, Shih JY, Lin CC, Chen KY, Ho CC, Laio WY, Yang PC, Yang JC. Bcl-2-like protein 11 deletion polymorphism predicts survival in advanced non-small-cell lung cancer. J Thorac Oncol. 2014 Sep; 9 (9; 2014 Sep):1385-92. [Full Text/Abstract]
Joseph J, Shamburek RD, Cochran EK, Gorden P, Brown RJ. Lipid Regulation in Lipodystrophy Versus the Obesity-Associated Metabolic Syndrome: The Dissociation of HDL-C and Triglycerides. J Clin Endocrinol Metab. 2014 Jun 13; 99 (99; 2014 Jun 13; 9):E1676-80. [Full Text/Abstract]
Chao HR, Lin DY, Chen KY, Gou YY, Chiou TH, Lee WJ, Chen SJ, Wang LC. Atmospheric concentrations of persistent organic pollutants over the Pacific Ocean near southern Taiwan and the northern Philippines. Sci Total Environ. 2014 Sep 1; 491-492 (491-492; 2014 Sep 1):51-9. [Full Text/Abstract]
Liu DJ, Hammer D, Komlos D, Chen KY, Firestein BL, Liu AY. SIRT1 Knockdown Promotes Neural Differentiation and Attenuates the Heat Shock Response. J Cell Physiol. 2014 Sep; 229 (229; 9; 2014 Sep):1224-35. [Full Text/Abstract]
Joseph J, Shamburek RD, Cochran EK, Gorden P, Brown RJ. Lipid Regulation in Lipodystrophy Versus the Obesity-Associated Metabolic Syndrome: The Dissociation of HDL-C and Triglycerides. J Clin Endocrinol Metab. 2014 Jun 13; 99 (99; 2014 Jun 13; 9):E1676-E1680. [Full Text/Abstract]
Karunasena HC, Senadeera W, Brown RJ, Gu YT. A particle based model to simulate microscale morphological changes of plant tissues during drying. Soft Matter. 2014 Aug 7; 10 (2014 Aug 7; 10; 29):5249-68. [Full Text/Abstract]
Quétel CR, Zampella M, Brown RJ, Ent H, Horvat M, Paredes E, Tunc M. International system of units traceable results of Hg mass concentration at saturation in air from a newly developed measurement procedure. Anal Chem. 2014 Aug 5; 86 (86; 2014 Aug 5; 15):7819-27. [Full Text/Abstract]
Lute B, Jou W, Lateef DM, Goldgof M, Xiao C, Piñol RA, Kravitz AV, Miller NR, Huang YG, Girardet C, Butler AA, Gavrilova O, Reitman ML. Biphasic effect of melanocortin agonists on metabolic rate and body temperature. Cell Metab. 2014 Aug 5; 20 (20; 2014 Aug 5; 2):333-45. [Full Text/Abstract]
Lute B, Jou W, Lateef DM, Goldgof M, Xiao C, Piñol RA, Kravitz AV, Miller NR, Huang YG, Girardet C, Butler AA, Gavrilova O, Reitman ML. Biphasic effect of melanocortin agonists on metabolic rate and body temperature. Cell Metab. 2014 Aug 5; 20 (20; 2014 Aug 5; 2):333-45. [Full Text/Abstract]
O'Connor MY, Thoreson CK, Ricks M, Courville AB, Thomas F, Yao J, Katzmarzyk PT, Sumner AE. Worse cardiometabolic health in African immigrant men than African American men: reconsideration of the healthy immigrant effect. Metab Syndr Relat Disord. 2014 Aug; 12 (6; 2014 Aug; 12):347-53. [Full Text/Abstract]
Chen KY, Wezenberg SJ, Carroll GT, London G, Kistemaker JC, Pijper TC, Feringa BL. Tetrapodal molecular switches and motors: synthesis and photochemistry. J Org Chem. 2014 Aug 1; 79 (15; 2014 Aug 1; 79):7032-40. [Full Text/Abstract]
Doerrbecker J, Friesland M, Riebesehl N, Ginkel C, Behrendt P, Brown RJ, Ciesek S, Wedemeyer H, Sarrazin C, Kaderali L, Pietschmann T, Steinmann E. Incorporation of primary patient-derived glycoproteins into authentic infectious hepatitis C virus particles. Hepatology. 2014 Aug; 60 (2; 2014 Aug; 60):508-20. [Full Text/Abstract]
Wang Z, Zhu B, Zhang M, Parikh H, Jia J, Chung CC, Sampson JN, Hoskins JW, Hutchinson A, Burdette L, Ibrahim A, Hautman C, Raj PS, Abnet CC, Adjei AA, Ahlbom A, Albanes D, Allen NE, Ambrosone CB, Aldrich M, Amiano P, Amos C, Andersson U, Andriole G Jr, Andrulis IL, Arici C, Arslan AA, Austin MA, Baris D, Barkauskas DA, Bassig BA, Beane Freeman LE, Berg CD, Berndt SI, Bertazzi PA, Biritwum RB, Black A, Blot W, Boeing H, Boffetta P, Bolton K, Boutron-Ruault MC, Bracci PM, Brennan P, Brinton LA, Brotzman M, Bueno-de-Mesquita HB, Buring JE, Butler MA, Cai Q, Cancel-Tassin G, Canzian F, Cao G, Caporaso NE, Carrato A, Carreon T, Carta A, Chang GC, Chang IS, Chang-Claude J, Che X, Chen CJ, Chen CY, Chen CH, Chen C, Chen KY, Chen YM, Chokkalingam AP, Chu LW, Clavel-Chapelon F, Colditz GA, Colt JS, Conti D, Cook MB, Cortessis VK, Crawford ED, Cussenot O, Davis FG, De Vivo I, Deng X, Ding T, Dinney CP, Di Stefano AL, Diver WR, Duell EJ, Elena JW, Fan JH, Feigelson HS, Feychting M, Figueroa JD, Flanagan AM, Fraumeni JF Jr, Freedman ND, Fridley BL, Fuchs CS, Gago-Dominguez M, Gallinger S, Gao YT, Gapstur SM, Garcia-Closas M, Garcia-Closas R, Gastier-Foster JM, Gaziano JM, Gerhard DS, Giffen CA, Giles GG, Gillanders EM, Giovannucci EL, Goggins M, Gokgoz N, Goldstein AM, Gonzalez C, Gorlick R, Greene MH, Gross M, Grossman HB, Grubb R 3rd, Gu J, Guan P, Haiman CA, Hallmans G, Hankinson SE, Harris CC, Hartge P, Hattinger C, Hayes RB, He Q, Helman L, Henderson BE, Henriksson R, Hoffman-Bolton J, Hohensee C, Holly EA, Hong YC, Hoover RN, Hosgood HD 3rd, Hsiao CF, Hsing AW, Hsiung CA, Hu N, Hu W, Hu Z, Huang MS, Hunter DJ, Inskip PD, Ito H, Jacobs EJ, Jacobs KB, Jenab M, Ji BT, Johansen C, Johansson M, Johnson A, Kaaks R, Kamat AM, Kamineni A, Karagas M, Khanna C, Khaw KT, Kim C, Kim IS, Kim YH, Kim YC, Kim YT, Kang CH, Jung YJ, Kitahara CM, Klein AP, Klein R, Kogevinas M, Koh WP, Kohno T, Kolonel LN, Kooperberg C, Kratz CP, Krogh V, Kunitoh H, Kurtz RC, Kurucu N, Lan Q, Lathrop M, Lau CC, Lecanda F, Lee KM, Lee MP, Le Marchand L, Lerner SP, Li D, Liao LM, Lim WY, Lin D, Lin J, Lindstrom S, Linet MS, Lissowska J, Liu J, Ljungberg B, Lloreta J, Lu D, Ma J, Malats N, Mannisto S, Marina N, Mastrangelo G, Matsuo K, McGlynn KA, McKean-Cowdin R, McNeill LH, McWilliams RR, Melin BS, Meltzer PS, Mensah JE, Miao X, Michaud DS, Mondul AM, Moore LE, Muir K, Niwa S, Olson SH, Orr N, Panico S, Park JY, Patel AV, Patino-Garcia A, Pavanello S, Peeters PH, Peplonska B, Peters U, Petersen GM, Picci P, Pike MC, Porru S, Prescott J, Pu X, Purdue MP, Qiao YL, Rajaraman P, Riboli E, Risch HA, Rodabough RJ, Rothman N, Ruder AM, Ryu JS, Sanson M, Schned A, Schumacher FR, Schwartz AG, Schwartz KL, Schwenn M, Scotlandi K, Seow A, Serra C, Serra M, Sesso HD, Severi G, Shen H, Shen M, Shete S, Shiraishi K, Shu XO, Siddiq A, Sierrasesumaga L, Sierri S, Loon Sihoe AD, Silverman DT, Simon M, Southey MC, Spector L, Spitz M, Stampfer M, Stattin P, Stern MC, Stevens VL, Stolzenberg-Solomon RZ, Stram DO, Strom SS, Su WC, Sund M, Sung SW, Swerdlow A, Tan W, Tanaka H, Tang W, Tang ZZ, Tardon A, Tay E, Taylor PR, Tettey Y, Thomas DM, Tirabosco R, Tjonneland A, Tobias GS, Toro JR, Travis RC, Trichopoulos D, Troisi R, Truelove A, Tsai YH, Tucker MA, Tumino R, Van Den Berg D, Van Den Eeden SK, Vermeulen R, Vineis P, Visvanathan K, Vogel U, Wang C, Wang C, Wang J, Wang SS, Weiderpass E, Weinstein SJ, Wentzensen N, Wheeler W, White E, Wiencke JK, Wolk A, Wolpin BM, Wong MP, Wrensch M, Wu C, Wu T, Wu X, Wu YL, Wunder JS, Xiang YB, Xu J, Yang HP, Yang PC, Yatabe Y, Ye Y, Yeboah ED, Yin Z, Ying C, Yu CJ, Yu K, Yuan JM, Zanetti KA, Zeleniuch-Jacquotte A, Zheng W, Zhou B, Mirabello L, Savage SA, Kraft P, Chanock SJ, Yeager M, Landi MT, Shi J, Chatterjee N, Amundadottir LT. Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. Hum Mol Genet. 2014 Jul 15; (2014 Jul 15). [Full Text/Abstract]
Chen KY, Chen CC, Tseng YL, Chang YC, Chang MC. GCIP functions as a tumor suppressor in non-small cell lung cancer by suppressing Id1-mediated tumor promotion. Oncotarget. 2014 Jul 15; 5 (2014 Jul 15; 13; 5):5017-28. [Full Text/Abstract]
Goldgof M, Xiao C, Chanturiya T, Jou W, Gavrilova O, Reitman ML. The Chemical Uncoupler 2,4-Dinitrophenol (DNP) Protects Against Diet-induced Obesity and Improves Energy Homeostasis in Mice at Thermoneutrality. J Biol Chem. 2014 Jul 11; 289 (28; 2014 Jul 11; 289):19341-50. [Full Text/Abstract]
van der Berg JD, Bosma H, Caserotti P, Eiriksdottir G, Arnardottir NY, Martin KR, Brychta RJ, Chen KY, Sveinsson T, Johannsson E, Launer LJ, Gudnason V, Jonsson PV, Stehouwer CD, Harris TB, Koster A. Midlife Determinants Associated with Sedentary Behavior in Old Age. Med Sci Sports Exerc. 2014 Jul; 46 (46; 7; 2014 Jul):1359-65. [Full Text/Abstract]
Chen JH, Chen KY, Hueng DY, Jin JS. Secondary pulmonary conventional chordoma arising from primary sarcomatoid chordoma of the sacrum: A case report. Oncol Lett. 2014 Jul; 8 (8; 2014 Jul; 1):208-210. [Full Text/Abstract]
Martin KR, Koster A, Murphy RA, Van Domelen DR, Hung MY, Brychta RJ, Chen KY, Harris TB. Changes in Daily Activity Patterns with Age in U.S. Men and Women: National Health and Nutrition Examination Survey 2003-04 and 2005-06. J Am Geriatr Soc. 2014 Jul; 62 (7; 62; 2014 Jul):1263-71. [Full Text/Abstract]
Troiano RP, McClain JJ, Brychta RJ, Chen KY. Evolution of accelerometer methods for physical activity research. Br J Sports Med. 2014 Jul; (2014 Jul). [Full Text/Abstract]
Brown RJ, Harris PM, Cox MG. Assessing the performance of standard methods to predict the standard uncertainty of air quality data having incomplete time coverage. Environ Sci Process Impacts. 2014 Jul; 16 (16; 7; 2014 Jul):1700-4. [Full Text/Abstract]
Guerrero AD, Dong MB, Zhao Y, Lau-Kilby A, Tarbell KV. Interleukin-2-mediated inhibition of dendritic cell development correlates with decreased CD135 expression and increased monocyte/macrophage precursors. Immunology. 2014 Jun 23; 143 (2014 Jun 23; 4; 143):640-50. [Full Text/Abstract]
Lee P, Smith S, Linderman J, Courville AB, Brychta RJ, Dieckmann W, Werner CD, Chen KY, Celi FS. Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans. Diabetes. 2014 Jun 22; 63 (2014 Jun 22; 63; 11):3686-98. [Full Text/Abstract]
Payne F, Lim K, Girousse A, Brown RJ, Kory N, Robbins A, Xue Y, Sleigh A, Cochran E, Adams C, Dev Borman A, Russel-Jones D, Gorden P, Semple RK, Saudek V, O'Rahilly S, Walther TC, Barroso I, Savage DB. Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease. Proc Natl Acad Sci U S A. 2014 Jun 17; 111 (111; 2014 Jun 17; 24):8901-6. [Full Text/Abstract]
Payne F, Lim K, Girousse A, Brown RJ, Kory N, Robbins A, Xue Y, Sleigh A, Cochran E, Adams C, Dev Borman A, Russel-Jones D, Gorden P, Semple RK, Saudek V, O'Rahilly S, Walther TC, Barroso I, Savage DB. Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease. Proc Natl Acad Sci U S A. 2014 Jun 17; (2014 Jun 17). [Full Text/Abstract]
Kim YH, Kim KH, Szulejko JE, Bae MS, Brown RJ. Experimental validation of an effective carbon number-based approach for the gas chromatography-mass spectrometry quantification of 'compounds lacking authentic standards or surrogates. Anal Chim Acta. 2014 Jun 9; 830C (830C; 2014 Jun 9):32-41. [Full Text/Abstract]
Li YJ, Hyun MH, Rha SW, Chen KY, Jin Z, Dang Q, Park CM, Lee JE, Park JY, Choi CU, Na JO, Lim HE, Kim JW, Kim EJ, Park CG, Seo HS, Oh DJ. Diabetes Mellitus is Not a Risk Factor for Coronary Artery Spasm as Assessed by an Intracoronary Acetylcholine Provocation Test: Angiographic and Clinical Characteristics of 986 Patients. J Invasive Cardiol. 2014 Jun; 26 (6; 26; 2014 Jun):234-239. [Full Text/Abstract]
Campfield B, Chen K, Kolls JK. Vaccine approaches for multidrug resistant Gram negative infections. Curr Opin Immunol. 2014 Jun; 28C (28C; 2014 Jun):84-89. [Full Text/Abstract]
Yang Y, Kuwano T, Lagor WR, Albert CJ, Brenton S, Rader DJ, Ford DA, Brown RJ. Lipidomic Analyses of Female Mice Lacking Hepatic Lipase and Endothelial Lipase Indicate Selective Modulation of Plasma Lipid Species. Lipids. 2014 Jun; 49 (6; 49; 2014 Jun):505-15. [Full Text/Abstract]
Friend DM, Kravitz AV. Working together: basal ganglia pathways in action selection. Trends Neurosci. 2014 Jun; 37 (6; 37; 2014 Jun):301-3. [Full Text/Abstract]
Chang SH, Chen KY, Wang LC. Identification and characterization of an asparaginyl endopeptidase from Angiostrongylus cantonensis. Parasitol Res. 2014 Jun; 113 (113; 6; 2014 Jun):2143-52. [Full Text/Abstract]
Krull AC, Shearer JK, Gorden PJ, Cooper VL, Phillips GJ, Plummer PJ. Deep Sequencing Analysis Reveals the Temporal Microbiota Changes Associated with the Development of Bovine Digital Dermatitis. Infect Immun. [Full Text/Abstract]
Lin WC, Fang SK, Hu JW, Tsai HY, Chen KY. Ratiometric Fluorescent/Colorimetric Cyanide-Selective Sensor Based on Excited-State Intramolecular Charge Transfer -Excited-State Intramolecular Proton Transfer Switching. Anal Chem. 2014 May 20; 86 (86; 2014 May 20; 10):4648-52. [Full Text/Abstract]
Nayeri A, Upah NC, Sucu E, Sanz-Fernandez MV, Defrain JM, Gorden PJ, Baumgard LH. Effect of zinc amino acid complex-to-zinc sulfate ratio on the performance of Holstein cows. J Dairy Sci. [Full Text/Abstract]
Basch E, Snyder C, McNiff K, Brown R, Maddux S, Smith ML, Atkinson TM, Howell D, Chiang A, Wood W, Levitan N, Wu AW, Krzyzanowska M. Patient-Reported Outcome Performance Measures in Oncology. J Oncol Pract. 2014 May; 10 (2014 May; 10; 3):209-11. [Full Text/Abstract]
Brown RJ, Yanovski JA. Estimation of insulin sensitivity in children: methods, measures and controversies. Pediatr Diabetes. 2014 May; 15 (2014 May; 15; 3):151-61. [Full Text/Abstract]
Cizza G, de Jonge L, Piaggi P, Mattingly M, Zhao X, Lucassen E, Rother KI, Sumner AE, Csako G. Neck circumference is a predictor of metabolic syndrome and obstructive sleep apnea in short-sleeping obese men and women. Metab Syndr Relat Disord. 2014 May; 12 (2014 May; 4; 12):231-41. [Full Text/Abstract]
Chen KY, Chen L, Mao J. Buprenorphine-naloxone therapy in pain management. Anesthesiology. 2014 May; 120 (120; 2014 May; 5):1262-74. [Full Text/Abstract]
Wang HN, Chen HD, Chen KY, Xiao JF, He K, Xiang GA, Xie X. Highly expressed MT-ND3 positively associated with histological severity of hepatic steatosis. APMIS. 2014 May; 122 (122; 2014 May; 5):443-51. [Full Text/Abstract]
Borresen EC, Gundlach KA, Wdowik M, Rao S, Brown RJ, Ryan EP. Feasibility of Increased Navy Bean Powder Consumption for Primary and Secondary Colorectal Cancer Prevention. Curr Nutr Food Sci. 2014 May; 10 (2; 2014 May; 10):112-119. [Full Text/Abstract]
Zhang M, Wu JF, Chen WJ, Tang SL, Mo ZC, Tang YY, Li Y, Wang JL, Liu XY, Peng J, Chen K, He PP, Lv YC, Ouyang XP, Yao F, Tang DP, Cayabyab FS, Zhang DW, Zheng XL, Tian GP, Tang CK. MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages. Atherosclerosis. 2014 May; 234 (2014 May; 234; 1):54-64. [Full Text/Abstract]
Chen KY, Sun J, Salvo JS, Baker D, Barth P. High-resolution modeling of transmembrane helical protein structures from distant homologues. PLoS Comput Biol. 2014 May; 10 (2014 May; 10; 5):e1003636. [Full Text/Abstract]
Brown RJ, Webb WR, Goddard SL. Observation of a physical matrix effect during cold vapour generation measurement of mercury in emissions samples. Anal Chim Acta. 2014 May 1; 823 (2014 May 1; 823):20-4. [Full Text/Abstract]
Brown RJ, Mustoe CL. Demonstration of a standard dilution technique for standard addition calibration. Talanta. 2014 May; 122 (122; 2014 May):97-100. [Full Text/Abstract]
Fox M, Ohlauson C, Sharpe AD, Brown RJ. The use of a Corophium volutator chronic sediment study to support the risk assessment of medetomidine for marine environments. Environ Toxicol Chem. 2014 Apr; 33 (33; 4; 2014 Apr):937-42. [Full Text/Abstract]