U.S. Department of Health and Human Services

Diabetes, Endocrinology, and Obesity Branch

Marc L. Reitman, M.D., Ph.D., Chief


A selection of recent and significant publications can be viewed below.

Price JD, Beauchamp NM, Rahir G, Zhao Y, Rieger CC, Lau-Kilby AW, Tarbell KV. CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L.J Leukoc Biol. ; 95 (95; 2) :325-36. [Full Text/Abstract]
Gardner JM, Metzger TC, McMahon EJ, Au-Yeung BB, Krawisz AK, Lu W, Price JD, Johannes KP, Satpathy AT, Murphy KM, Tarbell KV, Weiss A, Anderson MS. Extrathymic Aire-Expressing Cells Are a Distinct Bone Marrow-Derived Population that Induce Functional Inactivation of CD4(+) T Cells.Immunity. ; 39 (39; 3) :560-72. [Full Text/Abstract]
Mukherjee G, Geliebter A, Babad J, Santamaria P, Serreze DV, Freeman GJ, Tarbell KV, Sharpe A, Dilorenzo TP. DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8+ T cells independently of PD-1 and PD-L1. . [Full Text/Abstract]
Price JD, Linder G, Li WP, Zimmermann B, Rother KI, Malek R, Alattar M, Tarbell KV. Effects of Short-Term Sitagliptin Treatment on Immune Parameters in Healthy Individuals, A Randomized Placebo-Controlled Study.Clin. Exp. Immunol. 2013 May 27 (2013 May 27) . [Full Text/Abstract]
Kravitz AV, Owen SF, Kreitzer AC. Optogenetic identification of striatal projection neuron subtypes during in vivo recordings.Brain Res. 2013 May 20; 1511 (1511; 2013 May 20) :21-32. [Full Text/Abstract]
Yu SS, Ramsey NL, Castillo DC, Ricks M, Sumner AE. Triglyceride-based screening tests fail to recognize cardiometabolic disease in African immigrant and African-American men.Metab Syndr Relat Disord. 2013 Feb; 11 (2013 Feb; 11; 1) :15-20. [Full Text/Abstract]
Burke CJ, Huetteroth W, Owald D, Perisse E, Krashes MJ, Das G, Gohl D, Silies M, Certel S, Waddell S. Layered reward signalling through octopamine and dopamine in Drosophila.Nature. 2012 Dec 20; 492 (2012 Dec 20; 492; 7429) :433-7. [Full Text/Abstract]
Golden SH, Brown A, Cauley JA, Chin MH, Gary-Webb TL, Kim C, Sosa JA, Sumner AE, Anton B. Health disparities in endocrine disorders: biological, clinical, and nonclinical factors--an Endocrine Society scientific statement.J. Clin. Endocrinol. Metab. 2012 Sep; 97 (2012 Sep; 97; 9) :E1579-639. [Full Text/Abstract]
Reitman ML, Dishy V, Moreau A, Denney WS, Liu C, Kraft WK, Mejia AV, Matson MA, Stoch SA, Wagner JA, Lai E. Pharmacokinetics and pharmacodynamics of MK-5046, a bombesin receptor subtype-3 (BRS-3) agonist, in healthy patients.J Clin Pharmacol. 2012 Sep; 52 (2012 Sep; 9; 52) :1306-16. [Full Text/Abstract]
Sylvetsky AC, Welsh JA, Brown RJ, Vos MB. Low-calorie sweetener consumption is increasing in the United States.Am. J. Clin. Nutr. 2012 Sep; 96 (2012 Sep; 3; 96) :640-6. [Full Text/Abstract]
Brown RJ, Rother KI. Non-nutritive sweeteners and their role in the gastrointestinal tract.J. Clin. Endocrinol. Metab. 2012 Aug; 97 (2012 Aug; 8; 97) :2597-605. [Full Text/Abstract]
Foreyt J, Kleinman R, Brown RJ, Lindstrom R. The use of low-calorie sweeteners by children: implications for weight management.J. Nutr. 2012 Jun; 142 (2012 Jun; 6; 142) :1155S-62S. [Full Text/Abstract]
Butler PW, Cochran CS, Merino MJ, Nguyen DM, Schrump DS, Gorden P. Ectopic growth hormone-releasing hormone secretion by a bronchial carcinoid tumor: clinical experience following tumor resection and long-acting octreotide therapy.Pituitary. 2012 Jun; 15 (2012 Jun; 2; 15) :260-5. [Full Text/Abstract]
Kravitz AV, Kreitzer AC. Striatal mechanisms underlying movement, reinforcement, and punishment.Physiology (Bethesda). 2012 Jun; 27 (2012 Jun; 27; 3) :167-77. [Full Text/Abstract]
Castillo DC, Ramsey NL, Yu SS, Ricks M, Courville AB, Sumner AE. Inconsistent Access to Food and Cardiometabolic Disease: The Effect of Food Insecurity.Curr Cardiovasc Risk Rep. 2012 Jun; 6 (2012 Jun; 6; 3) :245-250. [Full Text/Abstract]
Kravitz AV, Tye LD, Kreitzer AC. Distinct roles for direct and indirect pathway striatal neurons in reinforcement.Nat. Neurosci. 2012 Jun; 15 (2012 Jun; 6; 15) :816-8. [Full Text/Abstract]
Brown RJ, Walter M, Rother KI. Effects of diet soda on gut hormones in youths with diabetes.Diabetes Care. 2012 May; 35 (2012 May; 35; 5) :959-64. [Full Text/Abstract]
Lungu AO, Zadeh ES, Goodling A, Cochran E, Gorden P. Insulin resistance is a sufficient basis for hyperandrogenism in lipodystrophic women with polycystic ovarian syndrome.J. Clin. Endocrinol. Metab. 2012 Feb; 97 (2012 Feb; 2; 97) :563-7. [Full Text/Abstract]
Muniyappa R, Sachdev V, Sidenko S, Ricks M, Castillo DC, Courville AB, Sumner AE. Postprandial endothelial function does not differ in women by race: an insulin resistance paradox?Am. J. Physiol. Endocrinol. Metab. 2012 Jan 15; 302 (2012 Jan 15; 2; 302) :E218-25. [Full Text/Abstract]
Hübner MP, Shi Y, Torrero MN, Mueller E, Larson D, Soloviova K, Gondorf F, Hoerauf A, Killoran KE, Stocker JT, Davies SJ, Tarbell KV, Mitre E. Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β.J. Immunol. 2012 Jan 15; 188 (188; 2012 Jan 15; 2) :559-68. [Full Text/Abstract]
Chen KY, Janz KF, Zhu W, Brychta RJ. Redefining the roles of sensors in objective physical activity monitoring.Med Sci Sports Exerc. 2012 Jan; 44 (1 Suppl 1; 44; 2012 Jan) :S13-23. [Full Text/Abstract]
Sylvetsky A, Rother KI, Brown R. Artificial sweetener use among children: epidemiology, recommendations, metabolic outcomes, and future directions.Pediatr. Clin. North Am. 2011 Dec; 58 (6; 58; 2011 Dec) :1467-80, xi. [Full Text/Abstract]
Ukegbu UJ, Castillo DC, Knight MG, Ricks M, Miller BV 3rd, Onumah BM, Sumner AE. Metabolic syndrome does not detect metabolic risk in African men living in the U.S.Diabetes Care. 2011 Oct; 34 (2011 Oct; 10; 34) :2297-9. [Full Text/Abstract]
Chow CC, Periwal V, Csako G, Ricks M, Courville AB, Miller BV 3rd, Vega GL, Sumner AE. Higher acute insulin response to glucose may determine greater free fatty acid clearance in African-American women.J. Clin. Endocrinol. Metab. 2011 Aug; 96 (8; 2011 Aug; 96) :2456-63. [Full Text/Abstract]
Semple RK, Savage DB, Cochran EK, Gorden P, O'Rahilly S. Genetic syndromes of severe insulin resistance.Endocr. Rev. 2011 Aug; 32 (32; 4; 2011 Aug) :498-514. [Full Text/Abstract]
Yadav H, Quijano C, Kamaraju AK, Gavrilova O, Malek R, Chen W, Zerfas P, Zhigang D, Wright EC, Stuelten C, Sun P, Lonning S, Skarulis M, Sumner AE, Finkel T, Rane SG. Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling.Cell Metab. 2011 Jul 6; 14 (2011 Jul 6; 14; 1) :67-79. [Full Text/Abstract]
Kravitz AV, Kreitzer AC. Optogenetic manipulation of neural circuitry in vivo.Curr. Opin. Neurobiol. 2011 Jun; 21 (2011 Jun; 21; 3) :433-9. [Full Text/Abstract]
Kim SY, Rane SG. The Cdk4-E2f1 pathway regulates early pancreas development by targeting Pdx1+ progenitors and Ngn3+ endocrine precursors.Development. 2011 May; 138 (138; 10; 2011 May) :1903-12. [Full Text/Abstract]
Kim YC, Kim SY, Mellado-Gil JM, Yadav H, Neidermyer W, Kamaraju AK, Rane SG. RB regulates pancreas development by stabilizing Pdx1.EMBO J. 2011 Apr 20; 30 (2011 Apr 20; 30; 8) :1563-76. [Full Text/Abstract]
Krashes MJ, Koda S, Ye C, Rogan SC, Adams AC, Cusher DS, Maratos-Flier E, Roth BL, Lowell BB. Rapid, reversible activation of AgRP neurons drives feeding behavior in mice.J. Clin. Invest. 2011 Apr; 121 (2011 Apr; 121; 4) :1424-8. [Full Text/Abstract]