U.S. Department of Health and Human Services

Kidney Diseases Section

Jeffrey B. Kopp, M.D., Chief

​Resources

Patents, materials, and other research resources appear below. Some resources may be available for use through Material Transfer Agreements (MTAs) or licensing agreements.

Resource Name Description
Podocin-rtTA (Tg(NPHS2-rtTA2*M2)1Jbk Mouse (Mutant Mouse: The tet transactivator (rtTA) gene placed under the control of the human NPHS2 gene).)

Reverse tetracycline-controlled transgenic mouse model (Tet-On) under the control of the specific promoter for the glomerular podocyte protein (Podocin, NPHS2).

Podocytes are post-mitotic epithelial cells that are positioned on the exterior aspect of…

(Summary)
Inducible podocyte-specific gene expression in transgenic mice (Podocin/rtTA DNA transgene)

The podocyte plays a key role in glomerular function and glomerular disease. To facilitate studies of podocyte function, we have developed a transgenic mouse model with inducible expression in the podocyte. The tetracycline-inducible transgenic…

(Summary)
View Additional Research Resources

Clinical Trials

Open studies conducted by NIDDK Principal Investigators appear below that are currently recruiting, not yet recruiting, or available for expanded access.