Chemical Biology in Signaling Section
Using chemical biology to develop new tools to interrogate cell surface proteins and their signaling
Select Publications
- Highly biased agonism for GPCR ligands via nanobody tethering.
- Sachdev S, Creemer BA, Gardella TJ, Cheloha RW.
- Nat Commun (2024 Jun 1) 15:4687. Abstract/Full Text
- Semi-synthetic nanobody-ligand conjugates exhibit tunable signaling properties and enhanced transcriptional outputs at neurokinin receptor-1.
- Braga Emidio N, Cheloha RW.
- Protein Sci (2024 Feb) 33:e4866. Abstract/Full Text
Last Reviewed February 2024