The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducts and supports basic and clinical research on many of the most serious diseases affecting public health.
NIDDK extramural research is organized into 3 programmatic divisions:
- Diabetes, Endocrinology, and Metabolic Diseases;
- Digestive Diseases and Nutrition; and
- Kidney, Urologic, and Hematologic Diseases.
The Institute supports basic and clinical research through investigator-initiated grants, program project and center grants, cooperative agreements, career development and training awards, and contracts.
NIDDK’s appropriation for fiscal year 2012 is $1.797 billion. This is an increase of 0.3% from NIDDK’s appropriation in fiscal year 2011.
NIDDK is committed to supporting as many meritorious competing research grant applications as possible. Consistent with NIH policy (see NIH Guide Notice NOT-OD-12-036), NIDDK will manage its portfolio in biomedical research investments in a manner that includes addressing the need for a highly productive pool of researchers by providing support for investigators who are at an early stage in their careers.
To maximize our available resources and to comply with NIH policy requiring that NIH Institutes and Centers strive to keep the average size of awards constant at FY 2011 levels or lower, all grant awards will continue to be subject to programmatic adjustments from the National Diabetes and Digestive and Kidney Diseases (NDDK) Advisory Council approved levels. These adjustments take into consideration the overall scientific and technical merit of the grant application, the cost of the proposed research, and other resources available for related research projects.
For FY 2012 NIDDK is establishing a nominal “payline” for new (Type 1) and renewal or competing continuation (Type 2) R01 applications of 13th percentile. Most R01 applications which have a primary assignment to NIDDK and which request less than $500,000 direct cost per year and score at or better than the 13th percentile will receive an award (applications which have NIDDK as a secondary assignment do not benefit from this payline). R01 applications requesting $500,000 or more in direct costs for any year will be held to a more stringent pay line – the 8th percentile for both Type 1 and 2 applications. It should be noted that NIDDK will exercise discretion and consider portfolio balance, programmatic importance and a number of other factors in determining precisely which applications are awarded. In addition, all grant awards will continue to be subject to programmatic adjustments from the NDDK Advisory Council approved levels. It is important to note that these funding levels are applicable for applications to be paid in FY 2012. Most applications submitted in FY 2012 (e.g., those submitted in January for September/October council consideration) will not be eligible for funding consideration until FY 2013. The funding levels for FY 2013 cannot now be reliably predicted.
Early Stage Investigators (ESIs)
Fostering the success of investigators establishing careers in biomedical research is a high priority of the NIDDK and NIH. In FY 2012 NIDDK will place special emphasis on supporting ESIs (investigators within 10-years of their terminal research degree or medical residency who have not yet been awarded a substantial, competing NIH research grant; (see ESI FAQs) by establishing a nominal payline for R01 applications submitted by ESIs at the 18th percentile. In addition, when possible and appropriate the full period of support recommended will be awarded.
In cases where a competing renewal application falls near but beyond the nominal payline, NIDDK will continue to consider interim support on a case-by-case basis and provide limited, support in selected cases. The goal is to preserve essential research resources pending the re-review of a revised application. NIDDK can choose to award a one- or two-year R56 grant to an R01 application scored outside the payline. These awards provide support for investigators to collect preliminary data and use these data to revise and improve their R01 applications.
Duration of Grant Support
Competing awards are adjusted to achieve a 4-year average duration for research project grants. Nevertheless, applications from ESIs, initial MERIT awards, MERIT extensions, program project grants, and clinical trial grants are generally awarded for the full length of their recommended project period.
Salaries on all grants are limited to $179,700 with issue dates on/after December 23, 2011 (see NOT-OD-12-035 - Notice of Salary Limitation on Grants, Cooperative Agreements, and Contracts). For grants with issue dates on/before December 22, 2011 the salary limitation is $199,700 for the FY2012 award period. Future years of all grants will be adjusted to reflect the $179,700 limit. Non-competing grants may re-budget any funds freed as a result of the lower cap.
Inflationary Increases for Future Years
Per the NIH Fiscal Policy for Grant Awards - FY2012 (NOT-OD-12-036), inflationary increases for future year commitments will be discontinued for all competing and non-competing research grant awards issued in FY 2012, however adjustments for special needs (such as equipment and added personnel) will continue to be accommodated.
Non-competing (Continuation) Awards
As required by the NIH Fiscal Policy for Grant Awards - FY2012 (NOT-OD-12-036
) non-competing (Type 5) awards will be issued without cost of living/inflationary adjustments in FY 2012; however adjustments for special needs (such as equipment and added personnel) will continue to be accommodated. This policy applies to all grants (research and non-research) when applicable.
Program Project (P01) Grant Applications and Applications with budgets greater than $500K
NIDDK has adopted a more stringent funding practice for awarding program project (P01) grants, Collaborative Interdisciplinary Team Science (R24) and other investigator-initiated grant applications with budgets of $500,000 requested direct costs in any one year. Prior approval is required before submitting an application for review that requests $500,000 or more in direct costs in any one year. The request to submit such applications should be received at least three months prior to the proposed submission date. Prior approval is required for renewal and revised applications as well as new applications. Please consult with the appropriate NIDDK program staff and visit the following site for information on research areas supported by NIDDK: http://www.niddk.nih.gov/research-funding/research-programs
New (Type 1) program project (P01) applications may request a maximum of $6.25 million in direct costs over five years, exclusive of the subcontract Facilities and Administrative (F&A) costs. Renewal [competing continuation (Type 2)] program project applications may request up to $6.25 million in direct costs over five years, exclusive of Facilities and Administrative (F&A) costs associated with the subcontract(s). In addition to the caps on the amount requested, P01 awards are subject to administrative adjustment from the Advisory Council approved levels. Also, any P01 grant receiving a competing award in FY 2011 or later will be limited to one subsequent renewal. Additional information regarding the P01 applications and their receipt dates can be found at: http://grants.nih.gov/grants/funding/ac_search_results.htm?text_curr=p01&Search_Type=Activity.