The National Institute of
Diabetes and Digestive and Kidney Diseases (NIDDK) conducts and supports basic
and clinical research on many of the most serious diseases affecting public
NIDDK extramural research
is organized into 3 programmatic divisions:
- Diabetes, Endocrinology, and
- Digestive Diseases and Nutrition; and
Urologic, and Hematologic Diseases.
The Institute supports
basic and clinical research through investigator-initiated grants, program
project and center grants, cooperative agreements, career development and
training awards, and contracts.
NIH is operating at a program level of $30.15
billion in FY 2014, an increase of $1 billion (+3.46%) over fiscal year (FY)
discretionary appropriation for FY 2014 is $1.744 billion. This is an increase
of about 3.01% from NIDDK’s appropriation in FY 2013. This figure does not include the FY 2014 Special Statutory Funding Program for Type 1 Diabetes Research appropriation of $139.2 M (-2.21% from FY 2013) that NIDDK oversees on behalf of NIH.
NIDDK is committed to supporting as
many meritorious competing research grant applications as possible. Consistent
with NIH policy (see NIH Guide Notice NOT-OD-14-055), NIDDK will manage its portfolio in
biomedical research investments in a manner that includes addressing the need
for a highly productive pool of researchers by providing support for investigators
who are at an early stage in their careers.
To maximize our
available resources, all grant awards will continue to be subject to
programmatic adjustments from the National Diabetes and Digestive and Kidney
Diseases (NDDK) Advisory Council approved levels. These adjustments take into
consideration the overall scientific and technical merit of the grant
application, the cost of the proposed research, and other resources available
for related research projects.
For FY 2014 NIDDK is
establishing a nominal “payline” for new (Type 1) and renewal or competing
continuation (Type 2) R01 applications of 13th percentile. Most R01
applications which have a primary assignment to NIDDK and which request less
than $500,000 direct cost per year and score at or better than the 13th percentile
will receive an award (applications which have NIDDK as a secondary assignment
do not benefit from this payline). R01 applications requesting $500,000
or more in direct costs for any year will be held to a more stringent pay line –
the 8th percentile for both Type 1 and 2 applications.
Please note the following regarding competing
- NIDDK will exercise discretion and consider portfolio balance,
programmatic importance and a number of other factors in determining precisely
which applications are awarded.
- All grant awards will continue to be subject to programmatic
adjustments from the NDDK Advisory Council approved levels.
- These funding levels are applicable for applications to be paid
in FY 2014. Many applications submitted
in FY 2014 (e.g., those submitted in January for September/October council
consideration) will not be eligible for funding consideration until FY 2015.
The funding levels for FY 2015 cannot now be reliably predicted.
Early Stage Investigators
Fostering the success of
investigators establishing careers in biomedical research is a high priority of
the NIDDK and NIH. In FY 2014 NIDDK will place special emphasis on supporting ESIs
(investigators within 10-years of their terminal research degree or medical
residency who have not yet been awarded a substantial, competing NIH research
grant; see ESI FAQs) by establishing a
nominal payline for R01 applications submitted by ESIs at the 18th
percentile. In addition, when possible and
appropriate the full period of support recommended will be awarded.
submitted by New Investigators who are not also ESIs will be paid up to the 13th
percentile (same as the general pay line).
In cases where a
competing renewal application falls near but beyond the nominal payline, NIDDK
will continue to consider interim support on a case-by-case basis and provide
limited support in selected cases. The goal is to preserve essential research
resources pending the re-review of a revised application. NIDDK can choose to
award a one- or two-year R56 grant to an R01 application scored outside the
payline. These awards provide support for investigators to collect preliminary
data and use these data to revise and improve their R01 applications.
Duration of Grant Support
Competing awards are
adjusted to achieve a 4-year average duration for research project grants.
Nevertheless, applications from ESIs, MERIT extensions, program project grants,
and clinical trial grants are generally
awarded for the full length of their recommended project period.
203 of the Consolidated Appropriations Act 2014
prohibits payments for salaries under grants and other extramural mechanisms in
excess of Executive Level II. It should be noted, that Executive Level II
was increased by 1 percent from $179,700 to $181,500 by Executive Order 13655 that became effective January 12, 2014. See NOT-OD-14-052 for
Per the NIH Fiscal Policy
for Grant Awards – 2014 (see NOT-OD-14-055) non-competing
(Type 5) continuation grants (research and non-research)
including those that remain to be issued in FY 2014 will likely be made at the
commitment level indicated on the Notice of Award (including those that were
initially issued at 90% of the commitment level in FY 2014). Out-year
commitments for continuation awards in FY 2015 and beyond will remain
Program Project (P01), Collaborative Interdisciplinary Team Science (R24), and Other Applications with Budgets Greater than $500K
NIDDK has adopted a more stringent
funding practice for awarding program project (P01) grants, Collaborative
Interdisciplinary Team Science (R24) and other investigator-initiated grant
applications with budgets of $500,000 requested direct costs in any one year.
Prior approval is required before submitting an application for review that
requests $500,000 or more in direct costs in any one year. The request to
submit such applications should be received at least three months prior to the
proposed submission date. Prior approval is required for renewal and revised
applications as well as new applications. Please consult with the appropriate
NIDDK program staff and visit the following site for information on research
areas supported by NIDDK: http://www.niddk.nih.gov/research-funding/research-programs/Pages/default.aspx.
New (Type 1) program
project (P01) applications may request a maximum of $6.25 million in direct
costs over five years, exclusive of the subcontract Facilities &
Administrative (F&A) costs. Renewal (competing continuation [Type 2])
program project applications may request up to $6.25 million in direct costs
over five years, exclusive of Facilities and Administrative (F&A) costs
associated with the subcontract(s). In addition to the caps on the amount
requested, P01 awards are subject to administrative adjustment from the
Advisory Council approved levels. Also, any P01 grant receiving a competing award in FY 2011 or later
will be limited to one subsequent renewal.