The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Program supports innovative research conducted by small businesses that has the potential for commercialization.
The funds for this program are ‘set-aside’ and therefore do not compete with the regular research, training, or other special programs supported by the Institute. The set-asides are set to increase over the next few years, and applicant success rates are high for this type of funding.
Jan. 27, 2015 - NIDDK will now accept Direct Phase II SBIR applications! - Already completed R&D that is characteristic of a Phase I SBIR project? We are now participating in PAR-14-088: "Direct Phase II SBIR Grants to Support Biomedical Technology Development (SBIR R44)". Contact Program Staff to discuss whether this avenue is right for you. Standard due dates apply.
Dec. 17, 2014 - Important! New Standard Due Dates for SBIR & STTR Applications - Standard due dates for SBIR & STTR applications have changed in order to make awards sooner on average. The next three standard due dates are April 5, 2015, September 5, 2015, and January 5, 2016. As always, it is important to confirm whether or not any particular funding opportunity uses the standard due dates.
Studying disease biology or develping a novel therapeutic? - NIDDK Program Directors have mapped NIDDK Funding Opportunities and related resources to critical stages along the therapeutic discovery and development pipeline. Find funding opportunities and resources best-suited to the current phase of your research, including SBIR & STTR FOAs for Lead Optimization and Pre-Clinical Development.
Dec. 18, 2014 - Funding Opportunity Reissued! - New Technologies for Viral Hepatitis SBIR (PA-15-077) & STTR (PA-15-076). Open for submissions March 5, 2015. Standard due dates apply.
Below, learn more about the SBIR and STTR funding mechanisms and find relevant upcoming meetings where you can find NIDDK's SBIR & STTR Program Directors.
SBIR & STTR
SBIR (R43/R44) grants are awarded to support research/research and development (R/R&D) efforts where the principal investigator is an employee of a small business.
STTR (R41/R42) grants support formal cooperative R/R&D efforts between small businesses and U.S. research institutions.
Application Types (Phase I, Phase II, Fast-Track, Phase IIB, Direct Phase II)
A Phase I SBIR (R43) or STTR (R41) grant is awarded to support studies establishing the technical/scientific merit and feasibility of the proposed R/R&D efforts.
Upon completion of Phase I, a Phase II SBIR (R44) or STTR (R42) grant may be awarded to support continuation of the R/R&D efforts initiated in Phase I. Phase II grants may be considerably larger than Phase I grants and require submission of a commercialization plan.
Fast-Track is an alternative pathway which expedites the decision and award of Phase II funding for scientifically meritorious applications that have a high potential for commercialization. The goals for Phase II must be clear, and the likelihood of Phase I success must be high, to be competitive. Fast-Track requires simultaneous submission of Phase I and Phase II applications. See NOT-OD-06-004 and the SBIR/STTR SF424 (R&R) Application Guide for more information.
NIDDK also offers the opportunity to apply for Phase IIB, Competing Renewal, SBIR grants, following completion of Phase II. These grants are offered to support projects that require regulatory approval for the product or service being developed or to support complex instrumentation, clinical research tools, and behavioral interventions/treatments.
Lastly, if you have already completed R&D that is characteristic of a Phase I SBIR project, demonstrating scientific and technical merit and feasibililty, you can apply for a Direct Phase II SBIR (See NOT-DK-15-006).
For a tabular comparison of these phases, including eligibility and requirements, please find links to the funding mechanisms pages under Additional Links, in the right-hand column.
Relevant Upcoming Meetings
Small business program directors are available at many national meetings, including the annual NIH-sponsored SBIR/STTR meeting for present and future applicants and awardees.
Digestive Disease Week 2015 - May 17-19, 2015 | Washington, DC. Small Business Program Directors from the Division of Digestive Diseases and Nutrition (DDN) will be in attendance. For details, please visit the conference website.
BIO International Convention 2015 - Jun 15-18, 2015 | Philadelphia, PA. For details, please visit the conference website.
17th Annual NIH SBIR/STTR Conference - Oct 27-29, 2015 | Seattle, WA. Some details are available at the Washington Life Science & Global Health Center website.
Recently Passed Meetings
56th American Society of Hematology Annual Meeting and Exposition - Dec 6-9, 2014 | San Francisco, CA. Small Business Program Directors from the Division of Kidney, Urologic, & Hematologic Diseases (KUH) will be in attendance. Find us at our booth. For details, please visit the conference website.
American Society of Nephrology Kidney Week - Nov 11-16, 2014 | Philadelphia, PA. Small Business Program Directors from the Division of Kidney, Urologic, & Hematologic Diseases (KUH) will be in attendance. Find us at poster NIH-3.
American Association for the Study of Liver Diseases: The Liver Meeting - Nov 7-11 | Boston, MA. Small Business Program Directors from the Division of Digestive Diseases and Nutrition (DDN) will be in attendance.
Diabetes Technology Meeting - Nov 6-8, 2014 | Bethesda, MD. Small Business Program Directors from the Division of Diabetes, Endocrine, and Metabolic Diseases (DEM) will be in attendance. For details, please visit the conference website.
16th Annual NIH SBIR/STTR Conference - Oct 21 – 23, 2014 | Albuquerque, NM. We are so glad to have met many current grantees and prospective applicants! You can find many of the slides presented at the conference website. Mouse-over 'Schedule', 'Session Descriptions', and select one of the tracks.