U.S. Department of Health and Human Services

Clinical Research in Type 1 Diabetes

The Clinical Research in Type 1 Diabetes program includes studies across the lifespan that address the etiology, pathogenesis, and treatment (medical- and self-management) of type 1 diabetes in youth and adults.  The program also supports research on hypoglycemia in T1D, including clinical studies and basic research using healthy individuals to understand the physiologic mechanisms of hypoglycemia. The program includes investigator-initiated clinical or behavioral studies, large, multi-center clinical trials that are conducted under cooperative agreements or contracts, and secondary analyses of ongoing clinical trials in diabetes and endocrinology.
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 NIDDK Staff

 
Beena Akolkar, Ph.D.Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 DiabetesCatherine Cowie, Ph.D., M.P.H.Epidemiology of diabetes, including development, control, interventions and complicationsChristine Hunter, Ph.D., ABPPBehavioral research on the prevention and treatment of obesity and diabetes; Centers for Diabetes Translational ResearchEllen Leschek, M.D.Type 1 diabetes clinical research; inborn errors of metabolism
Barbara Linder, M.D., Ph.D.Type 2 diabetes in children and youth; medical management of type 1 diabetes in youth and adults; human studies of the effect of the intrauterine environment on subsequent development of metabolic disease in offspring.Peter J. Savage, M.D.Clinical research in Type 1 and Type 2 Diabetes including secondary analyses; glycemic control and preservation of beta cell functionLisa M. Spain, Ph.D.Etiology and pathogenesis of type 1 diabetes and other autoimmune endocrine diseasesKaren L. Teff, Ph.D.Effects of bariatric surgery on diabetes and related metabolic outcomes; prevention, treatment and pathophysiology of hypoglycemia; effects of sleep on diabetes in humans

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
7/29/2015Type 1 Diabetes Pathfinder Award (DP2) (Summary) RFA-DK-15-030
7/28/2015Small Business Innovation Research (SBIR) to Develop New Methods and Technologies for Assessment of Risk and for Early Diagnosis and Prognosis of Type 1 Diabetes (T1D) (R43/R44) (Summary) RFA-DK-15-024
7/24/2015Small Business Innovation Research (SBIR) to Develop New or Improved Closed Loop Automated Technologies for Diabetes Therapy and Monitoring (R43/R44) (Summary) RFA-DK-15-022
7/17/2015Mouse Metabolic Phenotyping Centers Consortium (U2C) (Summary) RFA-DK-15-010
7/7/2015Mechanisms Underlying the Contribution of Type 1 Diabetes Risk Associated Variants (DP3) (Summary) RFA-DK-15-025
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled 5,145 overweight or obese participants with type 2 diabetes…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is to facilitate translation from the lab to the clinic of…
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that are linked to increased body fat in the child, and to a…

View Additional Research Resources

 

 NIDDK Active Trials in Type 1 Diabetes

 
​​View related clinical trials from ClinicalTrials.gov​.​

 

 Related Study Sections

 
​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections​ from the NIH's Center for Scientific Review.​​