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Clinical Research in Type 1 Diabetes

The Clinical Research in Type 1 Diabetes program includes studies across the lifespan that address the etiology, pathogenesis, and treatment (medical- and self-management) of type 1 diabetes in youth and adults.  The program also supports research on hypoglycemia in T1D, including clinical studies and basic research using healthy individuals to understand the physiologic mechanisms of hypoglycemia. The program includes investigator-initiated clinical or behavioral studies, large, multi-center clinical trials that are conducted under cooperative agreements or contracts, and secondary analyses of ongoing clinical trials in diabetes and endocrinology.
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 NIDDK Staff

 
Beena Akolkar, Ph.D.Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 DiabetesCatherine Cowie, Ph.D., M.P.H.Epidemiology of diabetes, including development, control, interventions and complicationsChristine Hunter, Ph.D., ABPPBehavioral research on the prevention and treatment of obesity and diabetes; Centers for Diabetes TranslationalEllen Leschek, M.D.Type 1 diabetes clinical research; inborn errors of metabolism
Barbara Linder, M.D., Ph.D.Type 2 diabetes in children and youth; medical management of type 1 diabetes in youth and adults; human studies of the effect of the intrauterine environment on subsequent development of metabolic disease in offspring.Peter J. Savage, Ph.D.Clinical research in Type 1 and Type 2 Diabetes including secondary analyses; glycemic control and preservation of beta cell functionLisa M. Spain, Ph.D.Etiology and pathogenesis of type 1 diabetes and other autoimmune endocrine diseasesKaren L. Teff, Ph.D.Prevention, treatment and pathophysiology of hypoglycemia; gestational diabetes; and the effects of bariatric surgery on diabetes and related outcomes

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
10/29/2014Administrative Supplements for Human Islet Research(Admin Supp) (Summary) PA-15-025
10/17/2014Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Clinical Centers (CSCPDPC -CCs) (U01) (Summary) RFA-DK-14-027
10/17/2014Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Coordination and Data Management Center (CSCPDPC- CDMC) (U01) (Summary) RFA-DK-14-028
9/30/2014Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4) (Summary) RFA-DK-14-508
9/24/2014Psychosocial and Behavioral Aspects of Bariatric Surgery (R01) (Summary) RFA-DK-14-026
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled 5,145 overweight or obese participants with type 2 diabetes…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is to facilitate translation from the lab to the clinic of…
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that are linked to increased body fat in the child, and to a…

View Additional Research Resources

 

 NIDDK Active Trials in Type 1 Diabetes

 
​​View related clinical trials from ClinicalTrials.gov​.​

 

 Related Study Sections

 
​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections​ from the NIH's Center for Scientific Review.​​