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Clinical Research in Type 1 Diabetes

The Clinical Research in Type 1 Diabetes program includes studies across the lifespan that address the etiology, pathogenesis, and treatment (medical- and self-management) of type 1 diabetes in youth and adults.  Supported within this program are basic and clinical studies to address mechanisms of hypoglycemia.  This program includes investigator-initiated clinical or behavioral studies, large, multi-center clinical trials that are conducted under cooperative agreements or contracts, and secondary analyses of ongoing clinical trials in diabetes and endocrinology.  ​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​

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 NIDDK Staff

 
Beena Akolkar, Ph.D.Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 DiabetesCatherine Cowie, Ph.D., M.P.H.Epidemiology of diabetes, including development, control, interventions and complicationsChristine Hunter, Ph.D., ABPPClinical research on behavioral treatments and prevention for obesity and diabetes; Centers for Diabetes Translational Research.Ellen Leschek, M.D.Type 1 diabetes clinical research; inborn errors of metabolism
Barbara Linder, M.D., Ph.D.Type 2 diabetes in children and youth; glycemic reduction approaches and hypoglycemia during pregnancy; metabolic imprintingPeter J. Savage, Ph.D.Clinical research in Type 1 and Type 2 Diabetes including secondary analyses; glycemic control and preservation of beta cell functionLisa M. Spain, Ph.D.Etiology and pathogenesis of type 1 diabetes and other autoimmune endocrine diseasesKaren L. Teff, Ph.D.Prevention, treatment and pathophysiology of hypoglycemia; gestational diabetes; and the effects of bariatric surgery on diabetes and related outcomes

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
6/25/2014NIDDK Mentored Research Scientist Development Award (K01) (Summary) PAR-14-266
6/25/2014Limited Competition: Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4) (Summary) RFA-DK-14-505
6/19/2014Improving Diabetes Management in Young Children with Type 1 Diabetes (DP3) (Summary) RFA-DK-14-022
6/11/2014Research Using Subjects From Selected Type 1 Diabetes Clinical Studies (Living Biobank) (DP3) (Summary) PAR-14-258
View More Funding Opportunities

 

 Research Resources

 
Resource NameDescription
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is … (Summary)
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that … (Summary)

Diabetes Prevention Program
The DPP showed that lifestyle change or metformin delay the development of type 2 diabetes. The DPPOS is a long-term follow-up study of the DPP participants.
(Summary)
Diabetes Prevention Program Outcomes Study
The Diabetes Prevention Program Outcomes Study is studying the long term effect of diet and exercise and the diabetes medication, metformin, on the delay of type 2 diabetes in participants of … (Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of … (Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Type 1 Diabetes

 
​​View related clinical trials from ClinicalTrials.gov​.​

 

 Related Study Sections

 
​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections​ from the NIH's Center for Scientific Review.​​