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Clinical Research in Type 2 Diabetes

The Clinical Research in Type 2 Diabetes program supports human studies across the lifespan aimed at the prevention and treatment of type 2 diabetes (T2D).  ​​​This program conducts clinical studies that advance the pharmacologic development of new drugs and surrogate markers for use in clinical trials that are designed to understand the pathophysiology of T2D—including the role of gestational diabetes and metabolic imprinting on the development of T2D—and to promote the preservation of beta cell function.  Also included are surgical treatments to prevent T2D in obese patients, medical and behavioral treatments to improve patient care and outcomes, epidemiologic studies, and the development of diagnostic criteria to distinguish type 1 and type 2 diabetes in the pediatric population.  The program supports research to define metabolic abnormalities and their natural history as well as studies that identify the basis for or test approaches to reduce racial/ethnic disparities in the incidence of TD2.​​
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 NIDDK Staff

 
Andrew BremerBasic science and clinical research focused on the prevention and treatment of type 2 diabetes; diet and exercise in the prevention and treatment of type 2 diabetesChristine Hunter, Ph.D., ABPPClinical research on behavioral treatments and prevention for obesity and diabetes; Centers for Diabetes Translational Research.Barbara Linder, M.D., Ph.D.Type 2 diabetes in children and youth; glycemic reduction approaches and hypoglycemia during pregnancy; metabolic imprinting
Peter J. Savage, Ph.D.Clinical research in Type 1 and Type 2 Diabetes including secondary analyses; glycemic control and preservation of beta cell functionMyrlene Staten, M.D.Pharmacologic interventions and/or other medically related interventions to prevent or treat Type 2 Diabetes in adult patientsKaren L. Teff, Ph.D.Prevention, treatment and pathophysiology of hypoglycemia; gestational diabetes; and the effects of bariatric surgery on diabetes and related outcomes

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
3/21/2014Limited Competition: Continuation of the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study (U01) (Summary) RFA-DK-14-502
3/12/2014Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study (DPPOS) (U01) (Summary) RFA-DK-14-501
3/7/2014Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) (Summary) PA-14-147
3/7/2014Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31 - Diversity) (Summary) PA-14-148
3/7/2014Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) (Summary) PA-14-149
View More Funding Opportunities

 

 Research Resources

 
Resource NameDescription
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of … (Summary)

Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that … (Summary)

Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in … (Summary)
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled … (Summary)
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  … (Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Type 2 Diabetes

 
​View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections ​from the NIH's Center for Scientific Review.