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The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of …
Sirt3 KO: Sirt3 is a mitochondrial-localized tumor suppressor that maintains mitochondrial integrity and metabolism during stress.
SirT3 is a mitochondrial protein that is …
Sirt1 knockout: Sirt1, a protein deacetylase, is a tumor suppressor that promotes genome stability and regulates proteins involved in energy metabolism.
Yeast Sir2, a nicotinamide …
M3 Muscarinic Receptor Knockout mice are hypophagic, lean, and have improved glucose tolerance and insulin sensitivity.
The five Muscarinic Acetylcholine (ACh) receptors …
Generation of a floxed Gnsa gene for the G-protein Gsα for the construction of conditional knockout mice.
The heterotrimeric G protein Gsa couples many receptors to adenylyl …
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