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Diabetes Genetics and Genomics

The Diabetes Genetics and Genomics program advances research to identify the genes that predispose individuals to develop type 1 or type 2 diabetes.  By determining the genetic mechanisms underlying these diseases—and how genetic and epigenetic variation influence therapeutic strategies—researchers should be able to develop better medications and therapies.  Studies can involve the use of animal models to identify the genes responsible for development of the disease; research to develop genetic resources; creation of animal models for therapeutic trials in type 1 diabetes; quantitative statistical and genetic methods to identify diabetes genes in human populations; investigation of the interactions of multiple genes and environmental factors; and research to examine the genetics underlying variation in response to diabetes drugs.  Also included in this program are studies that determine genetic differences between populations that result in health disparities.​​​​​

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 NIDDK Staff

 
Beena Akolkar, Ph.D.Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 Diabetes
Aaron Pawlyk, Ph.D.​Key regulators of intermediary metabolism; drug discovery; pharmacogenetics and precision medicine.

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
6/25/2014NIDDK Mentored Research Scientist Development Award (K01) (Summary) PAR-14-266
6/25/2014Limited Competition: Data Coordinating Center for The Environmental Determinants of Diabetes in the Young (TEDDY) Study (UC4) (Summary) RFA-DK-14-505
6/19/2014Improving Diabetes Management in Young Children with Type 1 Diabetes (DP3) (Summary) RFA-DK-14-022
6/11/2014Research Using Subjects From Selected Type 1 Diabetes Clinical Studies (Living Biobank) (DP3) (Summary) PAR-14-258
View More Funding Opportunities

​The resources listed below include reagents, data, protocols, etc.  If you would like to utilize any of these resources, contact the person associated with the resource.
 

 Research Resources

 
Resource NameDescription
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is … (Summary)
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that … (Summary)

Diabetes Prevention Program
The DPP showed that lifestyle change or metformin delay the development of type 2 diabetes. The DPPOS is a long-term follow-up study of the DPP participants.
(Summary)
Diabetes Prevention Program Outcomes Study
The Diabetes Prevention Program Outcomes Study is studying the long term effect of diet and exercise and the diabetes medication, metformin, on the delay of type 2 diabetes in participants of … (Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of … (Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Diabetes

 
View related clinical trials from ClinicalTrials.gov.​

 

 Related Study Sections

 
​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections​ from the NIH's Center for Scientific Review.