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Diabetes and Metabolism HIV/AIDS

The Diabetes and Metabolism HIV/AIDS program supports innovative basic science and clinical research on the role of HIV infection, including relevant host conditions, or antiretroviral therapy (ART) on metabolic and endocrine dysfunction. Specific areas of support include, but are not limited to:
 
•   Studies to elucidate the mechanisms underlying the effects of HIV and/or ART on metabolism (including glucose, lipid, and skeletal metabolism), body composition, and general endocrine function through basic and clinical research
 
•   Studies that elucidate novel approaches to prevent or manage diabetes and/or other endocrine disorders in HIV-infected individuals. However, such studies should target pathways unique to the development of these disorders in the context of HIV infection and/or its treatment rather than simply testing treatments accepted in non-HIV-infected individuals
 
•   Studies that elucidate the interactions between HIV, ART, and/or HIV-associated inflammation and diabetes-related medications to provide a basis for individualized therapy
 
•   Studies that determine the extent to which HIV and its therapy increase the risk of diabetes and/or other endocrine or metabolic dysfunction and identify factors which augment or ameliorate the risk
 
•   Studies that discover and validate biomarkers for metabolic and/or endocrine disease progression as a result of HIV infection or its treatment
 
•   Studies that employ non-invasive or minimally invasive means to assess tissue-specific or whole body metabolic changes in vivo due to HIV infection or therapy​​​​​​


 

 NIDDK Staff

 
Andrew BremerBasic science and clinical research focused on the prevention and treatment of type 2 diabetes; diet and exercise in the prevention of type 2 diabetes; HIV and HIV-treatment associated metabolic/endocrine dysfunction.
Saul MalozowskiNeuroendocrinology of hypothalamic-pituitary axis, neuropeptide signaling and receptors; hormonal regulation of bone and mineral metabolism

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
12/11/2014NIDDK Multi-Center Clinical Study Cooperative Agreement (U01) (Summary) PAR-15-067
12/11/2014NIDDK Multi-Center Clinical Study Implementation Planning Cooperative Agreements (U34) (Summary) PAR-15-068
11/26/2014NIH Big Data to Knowledge (BD2K) Initiative Research Education: Massive Open Online Course (MOOC) on Data Management for Biomedical Big Data (R25) (Summary) RFA-LM-15-001
11/26/2014NIH Big Data to Knowledge (BD2K) Initiative Research Education: Open Educational Resources for Sharing, Annotating and Curating Biomedical Big Data (R25) (Summary) RFA-LM-15-002
11/24/2014Underactive Bladder in Aging (R01) (Summary) PA-15-049
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled 5,145 overweight or obese participants with type 2 diabetes…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is to facilitate translation from the lab to the clinic of…
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that are linked to increased body fat in the child, and to a…

View Additional Research Resources

 

 NIDDK Active Trials in HIV/AIDS

 
View related clinical trials from ClinicalTrials.gov​.

 

 Related Study Sections

 
​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.​