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Diabetes: Treatment, Prevention, and Complications

The Diabetes: Treatment, Prevention, and Complications Program supports both basic and clinical studies aimed at addressing the prevention, treatment, and pathophysiology of hypoglycemia and diabetes.  Studies include lifestyle and other behavioral interventions to prevent or treat diabetes, such as approaches to improving health-related behaviors and to enhancing diabetes self-management and other aspects of diabetes care.  The Program examines the role of diet and exercise in the prevention and treatment of diabetes, as well as the outcomes of bariatric surgery as they relate to improved glycemia and remission of type 2 diabetes.  In the area of prevention of type 1 diabetes, research interests include studies on drug development and cellular therapy designed to prevent impaired glucose tolerance (IGT), arrest conversion of IGT to type 1 diabetes, enhance peripheral glucose metabolism or reduce hepatic glucose production, and increase insulin sensitivity.  This Program also encompasses basic and clinical research related to acute and chronic complications of type 1 and type 2 diabetes, such as the effects on the vascular and organ systems, as well as clinical studies that develop and evaluate strategies to prevent or treat these complications.​

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 NIDDK Staff

 
Beena Akolkar, Ph.D.Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 DiabetesAndrew BremerBasic science and clinical research focused on the prevention and treatment of type 2 diabetes; diet and exercise in the prevention and treatment of type 2 diabetesCatherine Cowie, Ph.D., M.P.H.Epidemiology of diabetes, including development, control, interventions and complicationsChristine Hunter, Ph.D., ABPPClinical research on behavioral treatments and prevention for obesity and diabetes; Centers for Diabetes Translational Research.
Teresa Jones, M.D.Basic and clinical research related to the complications of Type 1 and Type 2 diabetesBarbara Linder, M.D., Ph.D.Type 2 diabetes in children and youth; glycemic reduction approaches and hypoglycemia during pregnancy; metabolic imprintingPeter J. Savage, Ph.D.Clinical research in Type 1 and Type 2 Diabetes including secondary analyses; glycemic control and preservation of beta cell functionKaren L. Teff, Ph.D.Prevention, treatment and pathophysiology of hypoglycemia; gestational diabetes; and the effects of bariatric surgery on diabetes and related outcomes

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
7/30/2014NIDDK Central Repositories Non-renewable Sample Access (X01) (Summary) PAR-14-301
7/21/2014Advanced Clinical Trials to test Artificial Pancreas Device Systems in Type 1 Diabetes (UC4) (Summary) RFA-DK-14-024
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
7/2/2014NIAID SBIR - Technology Transfer Direct Phase II (SBIR-TT) (R44) - See more at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-14-049.html#sthash.5IEWBI1W.dpuf (Summary) RFA-AI-14-049
6/25/2014NIDDK Mentored Research Scientist Development Award (K01) (Summary) PAR-14-266
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 Research Resources

 
Resource NameDescription
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is … (Summary)
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that … (Summary)

Diabetes Prevention Program
The DPP showed that lifestyle change or metformin delay the development of type 2 diabetes. The DPPOS is a long-term follow-up study of the DPP participants.
(Summary)
Diabetes Prevention Program Outcomes Study
The Diabetes Prevention Program Outcomes Study is studying the long term effect of diet and exercise and the diabetes medication, metformin, on the delay of type 2 diabetes in participants of … (Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of … (Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Diabetes

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.