U.S. Department of Health and Human Services
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Diabetic Kidney Disease

The Diabetic Kidney Disease program advances basic research, natural history studies, and clinical trials.  Fundamental research addresses the molecular pathogenesis of extracellular matrix expansion and glomerulosclerosis.  Also of interest are studies on the role of the renin-angiotensin system, growth factors, and cell signaling pathways.  The portfolio aims to prevent, reverse, and ameliorate fibrosis.  Specific projects include studies that investigate the mechanisms of fibrosis and use of noninvasive imaging techniques to assess fibrosis.  Other work seeks to discover genes that protect people from or predispose them to diabetic nephropathy and identify early markers of increased risk for this disease.​​​​​​​​

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 NIDDK Staff

 
Michael Flessner, M.D., Ph.D.Clinical CKD; Glomerular Disease; Clinical PKD; PKD CentersDeborah Hoshizaki, Ph.D.Kidney and Urogenital Development; Kidney and Urology Regeneration and Repair; Urology CentersChris Ketchum, Ph.D.Deputy Director, KUH Basic Science; Renal Physiology
Paul L. Kimmel, M.D.Clinical AKI; Kidney Translational Genetics; Kidney Centers; Kidney HIV/AIDSKrystyna Rys-Sikora, Ph.D.Basic AKI and CKD

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
10/17/2014Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Clinical Centers (CSCPDPC -CCs) (U01) (Summary) RFA-DK-14-027
10/17/2014Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer Coordination and Data Management Center (CSCPDPC- CDMC) (U01) (Summary) RFA-DK-14-028
10/3/2014Innovative Research in HIV in Kidney, Urology and Hematology (R01) (Summary) RFA-DK-14-020
9/30/2014Limited Competition for the Continuation of the SEARCH for Diabetes in Youth Cohort Study (UC4) (Summary) RFA-DK-14-508
9/24/2014Psychosocial and Behavioral Aspects of Bariatric Surgery (R01) (Summary) RFA-DK-14-026
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
(Summary)
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled 5,145 overweight or obese participants with type 2 diabetes…
(Summary)
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
(Summary)
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is to facilitate translation from the lab to the clinic of…
(Summary)
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that are linked to increased body fat in the child, and to a…

(Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Diabetes

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.