U.S. Department of Health and Human Services
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Diabetic Kidney Disease

The Diabetic Kidney Disease program advances basic research, natural history studies, and clinical trials.  Fundamental research addresses the molecular pathogenesis of extracellular matrix expansion and glomerulosclerosis.  Also of interest are studies on the role of the renin-angiotensin system, growth factors, and cell signaling pathways.  The portfolio aims to prevent, reverse, and ameliorate fibrosis.  Specific projects include studies that investigate the mechanisms of fibrosis and use of noninvasive imaging techniques to assess fibrosis.  Other work seeks to discover genes that protect people from or predispose them to diabetic nephropathy and identify early markers of increased risk for this disease.​​​​​​​​

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 NIDDK Staff

 
Michael Flessner, M.D., Ph.D.Clinical CKD; Glomerular Disease; Clinical PKD; PKD CentersDeborah Hoshizaki, Ph.D.Kidney and Urogenital Development; Kidney and Urology Regeneration and Repair; Urology CentersChris Ketchum, Ph.D.Deputy Director, KUH Basic Science; Renal Physiology
Paul L. Kimmel, M.D.Clinical AKI; Kidney Translational Genetics; Kidney Centers; Kidney HIV/AIDSKrystyna Rys-Sikora, Ph.D.Basic AKI and CKD

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
7/30/2014NIDDK Central Repositories Non-renewable Sample Access (X01) (Summary) PAR-14-301
7/21/2014Advanced Clinical Trials to test Artificial Pancreas Device Systems in Type 1 Diabetes (UC4) (Summary) RFA-DK-14-024
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
7/2/2014Innovative Therapies and Tools for Screenable Disorders in Newborns (R01) (Summary) PAR-14-270
7/2/2014NIAID SBIR - Technology Transfer Direct Phase II (SBIR-TT) (R44) - See more at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-14-049.html#sthash.5IEWBI1W.dpuf (Summary) RFA-AI-14-049
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​The resources listed below include reagents, data, protocols, etc.  If you would like to utilize any of these resources, contact the person associated with the resource.
 

 Research Resources

 
Resource NameDescription
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is … (Summary)
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that … (Summary)

Diabetes Prevention Program
The DPP showed that lifestyle change or metformin delay the development of type 2 diabetes. The DPPOS is a long-term follow-up study of the DPP participants.
(Summary)
Diabetes Prevention Program Outcomes Study
The Diabetes Prevention Program Outcomes Study is studying the long term effect of diet and exercise and the diabetes medication, metformin, on the delay of type 2 diabetes in participants of … (Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of … (Summary)

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 NIDDK Active Trials in Diabetes

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.