The Diabetic Urologic Disease program advances basic research on natural history studies and clinical trials. Fundamental research addresses how diabetes affects the bladder, prostate, urinary tract, and lower reproductive system. Program-supported work includes studies in human cells as well as in mammalian and nonmammalian model organisms. Specific projects include studies that investigate the mechanisms of fibrosis and use noninvasive imaging techniques to assess fibrosis.
Other work seeks to discover genes that protect people from or predispose them to diabetic uropathy and identify early markers of increased risk for this disease.