The Diabetic Urologic Disease program advances basic research on natural history studies and clinical trials. Fundamental research addresses how diabetes affects the bladder, prostate, urinary tract, and male sexual function.
This program supports studies in human cells as well as in mammalian and non-mammalian model organisms on the molecular mechanims of diabetic uropathy and uncover the intersection between these mechanisms and hormonal control of prostate growth and male sexual function. Specific projects also investigate the mechanisms of fibrosis and use noninvasive techniques to assess fibrosis.
Other work seeks to discover genes that protect people from or predispose them to diabetic uropathy and identify early markers of increased risk for this disease.